Patents by Inventor Arthur C. Watterson
Arthur C. Watterson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11850323Abstract: A solidifying prepolymeric implant composition comprising a biocompatible prepolymer and an optional filler. One such implant composition is a polyurethane implant composition comprising an isocyanate, such as hydroxymethylenediisocyanate (HMDI) and an alcohol, such as polycaprolactonediol (PCL diol). The compositions of the invention are useful for improving bone structure in patients by applying the solidifying implant composition to bone, reinforcing bone structure, improving load bearing capacity and/or aiding healing of microfractures.Type: GrantFiled: December 7, 2020Date of Patent: December 26, 2023Assignee: 206 ORTHO, INC.Inventors: Jeffrey A. D'Agostino, Andrew J. Carter, Craig M. Jones, Arthur C. Watterson
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Publication number: 20210178016Abstract: A solidifying prepolymeric implant composition comprising a biocompatible prepolymer and an optional filler. One such implant composition is a polyurethane implant composition comprising an isocyanate, such as hydroxymethylenediisocyanate (HMDI) and an alcohol, such as polycaprolactonediol (PCL diol). The compositions of the invention are useful for improving bone structure in patients by applying the solidifying implant composition to bone, reinforcing bone structure, improving load bearing capacity and/or aiding healing of microfractures.Type: ApplicationFiled: December 7, 2020Publication date: June 17, 2021Inventors: Jeffrey A. D'Agostino, Andrew J. Carter, Craig M. Jones, Arthur C. Watterson
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Patent number: 10857261Abstract: A solidifying prepolymeric implant composition comprising a biocompatible prepolymer and an optional filler. One such implant composition is a polyurethane implant composition comprising an isocyanate, such as hydroxymetbylenediisocyanate (HMDI) and an alcohol, such as polycaprolactonediol (PCL diol). The compositions of the invention are useful for improving bone structure in patients by applying the solidifying implant composition to bone, reinforcing bone structure, improving load bearing capacity and/or aiding healing of microfractures.Type: GrantFiled: May 17, 2016Date of Patent: December 8, 2020Assignee: 206 ORTHO, Inc.Inventors: Jeffrey A. D'Agostino, Andrew J. Carter, Craig M. Jones, Arthur C. Watterson
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Publication number: 20160256602Abstract: A solidifying prepolymeric implant composition comprising a biocompatible prepolymer and an optional filler. One such implant composition is a polyurethane implant composition comprising an isocyanate, such as hydroxymetbylenediisocyanate (HMDI) and an alcohol, such as polycaprolactonediol (PCL diol). The compositions of the invention are useful for improving bone structure in patients by applying the solidifying implant composition to bone, reinforcing bone structure, improving load bearing capacity and/or aiding healing of microfractures.Type: ApplicationFiled: May 17, 2016Publication date: September 8, 2016Inventors: Jeffrey A. D'Agostino, Andrew J. Carter, Craig M. Jones, Arthur C. Watterson
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Patent number: 9156945Abstract: A polymer is characterized by a repeat unit represented by Structural Formula (I): or a copolymer thereof. A crosslinked polymer characterized by a repeat unit represented by Structural Formula (II), (III), (IV) or (V): or a copolymer thereof, wherein at least one such repeat unit of a first polymer strand is crosslinked with at least one repeat unit of a second polymer strand by at least one bridging unit, the first and second polymer strands and the repeat unit being components of the crosslinked polymer.Type: GrantFiled: May 14, 2013Date of Patent: October 13, 2015Assignees: University of Massachusetts, The United States of America, as Represented by the Secretary of the ArmyInventors: Arthur C. Watterson, Ravi Mosurkal, Jayant Kumar, Virinder S. Parmar, Lynne A. Samuelson, Rajesh Kumar, Vincent B. Tucci
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Publication number: 20140178328Abstract: A solidifying prepolymeric implant composition comprising a biocompatible prepolymer and an optional filler. One such implant composition is a polyurethane implant composition comprising an isocyanate, such as hydroxymethylenediisocyanate (HMDI) and an alcohol, such as polycaprolactonediol (PCL diol). The compositions of the invention are useful for improving bone structure in patients by applying the solidifying implant composition to bone, reinforcing bone structure, improving load bearing capacity and/or aiding healing of microfractures.Type: ApplicationFiled: February 28, 2014Publication date: June 26, 2014Applicant: 206 ORTHO, Inc.Inventors: Jeffrey A. D'Agostino, Andrew J. Carter, Craig M. Jones, Arthur C. Watterson
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Publication number: 20140088270Abstract: A polymer is characterized by a repeat unit represented by Structural Formula (I): or a copolymer thereof. A crosslinked polymer characterized by a repeat unit represented by Structural Formula (II), (III), (IV) or (V): or a copolymer thereof, wherein at least one such repeat unit of a first polymer strand is crosslinked with at least one repeat unit of a second polymer strand by at least one bridging unit, the first and second polymer strands and the repeat unit being components of the crosslinked polymer.Type: ApplicationFiled: May 14, 2013Publication date: March 27, 2014Applicants: The Government of the United States, as Represented by the Secretary of the Army, University of MassachusettsInventors: Arthur C. Watterson, Ravi Mosurkal, Jayant Kumar, Virinder S. Parmar, Lynne A. Samuelson, Rajesh Kumar, Vincent B. Tucci
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Publication number: 20120263797Abstract: A solidifying prepolymeric implant composition comprising a biocompatible prepolymer and an optional filler. One such implant composition is a polyurethane implant composition comprising an isocyanate, such as hydroxymethylenediisocyanate (HMDI) and an alcohol, such as polycaprolactonediol (PCL diol). The compositions of the invention are useful for improving bone structure in patients by applying the solidifying implant composition to bone, reinforcing bone structure, improving load bearing capacity and/or aiding healing of microfractures.Type: ApplicationFiled: April 20, 2012Publication date: October 18, 2012Applicant: BIOS2 Medical, Inc.Inventors: Jeffrey A. D'Agostino, Andrew J. Carter, Craig M. Jones, Arthur C. Watterson
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Publication number: 20120100583Abstract: The invention relates to new methods of enzymatic synthesis of polymers such as polyorganosilicones and polyesters, and new polymers made by these methods.Type: ApplicationFiled: May 24, 2011Publication date: April 26, 2012Applicant: UNIVERSITY OF MASSACHUSETTSInventors: Rajesh Kumar, Arthur C. Watterson, Virinder Singh Parmar, Jayant Kumar, Lynne Ann Samuelson
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Publication number: 20110136958Abstract: A polymer is characterized by a repeat unit represented by Structural Formula (I), or a copolymer thereof. A crosslinked polymer characterized by a repeat unit represented by Structural Formula (II), (III), (IV) or (V), or a copolymer thereof, wherein at least one such repeat unit of a first polymer strand is crosslinked with at least one repeat unit of a second polymer strand by at least one bridging unit, the first and second polymer strands and the repeat unit being components of the crosslinked polymer.Type: ApplicationFiled: September 10, 2008Publication date: June 9, 2011Inventors: Arthur C. Watterson, Ravi Mosurkal, Jayant Kumar, Virinder S. Parmar, Lynne A. Samuelson, Rajesh Kumar, Vincent Tucci
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Publication number: 20100310647Abstract: The invention relates to new methods of enzymatic synthesis of polymers such as polyorganosilicones and polyesters, and new polymers made by these methods.Type: ApplicationFiled: May 5, 2010Publication date: December 9, 2010Applicant: UNIVERSITY OF MASSACHUSETTSInventors: Rajesh Kumar, Arthur C. Watterson, Virinder Singh Parmar, Jayant Kumar, Lynne Ann Samuelson
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Publication number: 20090099267Abstract: Polymers having a main chain having both aromatic units and aliphatic units (with repeating heteroatoms) and a side chain macromonomer are described. Methods of making these polymers using enzymatic synthesis and the applications of these polymers are also described.Type: ApplicationFiled: May 26, 2006Publication date: April 16, 2009Applicant: University of MassachusettsInventors: Rajesh Kumar, Jayant Kumar, Virinder Singh Parmar, Arthur C. Watterson
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Patent number: 6962963Abstract: The invention relates to new methods of enzymatic synthesis of polymers such as polyorganosilicones and polyesters, and new polymers made by these methods.Type: GrantFiled: October 17, 2003Date of Patent: November 8, 2005Assignee: University of MassachusettsInventors: Rajesh Kumar, Arthur C. Watterson, Virinder Singh Parmar, Jayant Kumar, Lynne Ann Samuelson
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Publication number: 20040152176Abstract: The invention relates to new methods of enzymatic synthesis of polymers such as polyorganosilicones and polyesters, and new polymers made by these methods.Type: ApplicationFiled: October 17, 2003Publication date: August 5, 2004Inventors: Rajesh Kumar, Arthur C. Watterson, Virinder Singh Parmar, Jayant Kumar, Lynne Ann Samuelson
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Publication number: 20030144458Abstract: The invention is based in part on the discovery of polymers that can complex with certain types of therapeutic drugs and transport those drugs across cell membranes in cell cultures with demonstrable therapeutic activity. The polymers are designed to overcome some of the known problems of liposomes as drug carriers. The polymers can be used in the development of physiologically stable, non-leaking, non-immunogenic, efficacious and safe targetable drug delivery systems (e.g., for delivery of anti-HIV or anticancer drugs).Type: ApplicationFiled: January 27, 2003Publication date: July 31, 2003Applicant: University of Massachusetts, a Massachusetts corporationInventors: Arthur C. Watterson, Kunya Danprasert, Anil Diwan
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Patent number: 6521736Abstract: The invention is based in part on the discovery of polymers that can complex with certain types of therapeutic drugs and transport those drugs across cell membranes in cell cultures with demonstrable therapeutic activity. The polymers are designed to overcome some of the known problems of liposomes as drug carriers. The polymers can be used in the development of physiologically stable, non-leaking, non-immunogenic, efficacious and safe targetable drug delivery systems (e.g., for delivery of anti-HIV or anticancer drugs).Type: GrantFiled: September 14, 2001Date of Patent: February 18, 2003Assignee: University of MassachusettsInventors: Arthur C. Watterson, Kunya Danprasert, Anil Diwan
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Publication number: 20020099164Abstract: The invention is based in part on the discovery of polymers that can complex with certain types of therapeutic drugs and transport those drugs across cell membranes in cell cultures with demonstrable therapeutic activity. The polymers are designed to overcome some of the known problems of liposomes as drug carriers. The polymers can be used in the development of physiologically stable, non-leaking, non-immunogenic, efficacious and safe targetable drug delivery systems (e.g., for delivery of anti-HIV or anticancer drugs).Type: ApplicationFiled: September 14, 2001Publication date: July 25, 2002Inventors: Arthur C. Watterson, Kunya Danprasert, Anil Diwan