Patents by Inventor Arthur C. Watterson

Arthur C. Watterson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11850323
    Abstract: A solidifying prepolymeric implant composition comprising a biocompatible prepolymer and an optional filler. One such implant composition is a polyurethane implant composition comprising an isocyanate, such as hydroxymethylenediisocyanate (HMDI) and an alcohol, such as polycaprolactonediol (PCL diol). The compositions of the invention are useful for improving bone structure in patients by applying the solidifying implant composition to bone, reinforcing bone structure, improving load bearing capacity and/or aiding healing of microfractures.
    Type: Grant
    Filed: December 7, 2020
    Date of Patent: December 26, 2023
    Assignee: 206 ORTHO, INC.
    Inventors: Jeffrey A. D'Agostino, Andrew J. Carter, Craig M. Jones, Arthur C. Watterson
  • Publication number: 20210178016
    Abstract: A solidifying prepolymeric implant composition comprising a biocompatible prepolymer and an optional filler. One such implant composition is a polyurethane implant composition comprising an isocyanate, such as hydroxymethylenediisocyanate (HMDI) and an alcohol, such as polycaprolactonediol (PCL diol). The compositions of the invention are useful for improving bone structure in patients by applying the solidifying implant composition to bone, reinforcing bone structure, improving load bearing capacity and/or aiding healing of microfractures.
    Type: Application
    Filed: December 7, 2020
    Publication date: June 17, 2021
    Inventors: Jeffrey A. D'Agostino, Andrew J. Carter, Craig M. Jones, Arthur C. Watterson
  • Patent number: 10857261
    Abstract: A solidifying prepolymeric implant composition comprising a biocompatible prepolymer and an optional filler. One such implant composition is a polyurethane implant composition comprising an isocyanate, such as hydroxymetbylenediisocyanate (HMDI) and an alcohol, such as polycaprolactonediol (PCL diol). The compositions of the invention are useful for improving bone structure in patients by applying the solidifying implant composition to bone, reinforcing bone structure, improving load bearing capacity and/or aiding healing of microfractures.
    Type: Grant
    Filed: May 17, 2016
    Date of Patent: December 8, 2020
    Assignee: 206 ORTHO, Inc.
    Inventors: Jeffrey A. D'Agostino, Andrew J. Carter, Craig M. Jones, Arthur C. Watterson
  • Publication number: 20160256602
    Abstract: A solidifying prepolymeric implant composition comprising a biocompatible prepolymer and an optional filler. One such implant composition is a polyurethane implant composition comprising an isocyanate, such as hydroxymetbylenediisocyanate (HMDI) and an alcohol, such as polycaprolactonediol (PCL diol). The compositions of the invention are useful for improving bone structure in patients by applying the solidifying implant composition to bone, reinforcing bone structure, improving load bearing capacity and/or aiding healing of microfractures.
    Type: Application
    Filed: May 17, 2016
    Publication date: September 8, 2016
    Inventors: Jeffrey A. D'Agostino, Andrew J. Carter, Craig M. Jones, Arthur C. Watterson
  • Patent number: 9156945
    Abstract: A polymer is characterized by a repeat unit represented by Structural Formula (I): or a copolymer thereof. A crosslinked polymer characterized by a repeat unit represented by Structural Formula (II), (III), (IV) or (V): or a copolymer thereof, wherein at least one such repeat unit of a first polymer strand is crosslinked with at least one repeat unit of a second polymer strand by at least one bridging unit, the first and second polymer strands and the repeat unit being components of the crosslinked polymer.
    Type: Grant
    Filed: May 14, 2013
    Date of Patent: October 13, 2015
    Assignees: University of Massachusetts, The United States of America, as Represented by the Secretary of the Army
    Inventors: Arthur C. Watterson, Ravi Mosurkal, Jayant Kumar, Virinder S. Parmar, Lynne A. Samuelson, Rajesh Kumar, Vincent B. Tucci
  • Publication number: 20140178328
    Abstract: A solidifying prepolymeric implant composition comprising a biocompatible prepolymer and an optional filler. One such implant composition is a polyurethane implant composition comprising an isocyanate, such as hydroxymethylenediisocyanate (HMDI) and an alcohol, such as polycaprolactonediol (PCL diol). The compositions of the invention are useful for improving bone structure in patients by applying the solidifying implant composition to bone, reinforcing bone structure, improving load bearing capacity and/or aiding healing of microfractures.
    Type: Application
    Filed: February 28, 2014
    Publication date: June 26, 2014
    Applicant: 206 ORTHO, Inc.
    Inventors: Jeffrey A. D'Agostino, Andrew J. Carter, Craig M. Jones, Arthur C. Watterson
  • Publication number: 20140088270
    Abstract: A polymer is characterized by a repeat unit represented by Structural Formula (I): or a copolymer thereof. A crosslinked polymer characterized by a repeat unit represented by Structural Formula (II), (III), (IV) or (V): or a copolymer thereof, wherein at least one such repeat unit of a first polymer strand is crosslinked with at least one repeat unit of a second polymer strand by at least one bridging unit, the first and second polymer strands and the repeat unit being components of the crosslinked polymer.
    Type: Application
    Filed: May 14, 2013
    Publication date: March 27, 2014
    Applicants: The Government of the United States, as Represented by the Secretary of the Army, University of Massachusetts
    Inventors: Arthur C. Watterson, Ravi Mosurkal, Jayant Kumar, Virinder S. Parmar, Lynne A. Samuelson, Rajesh Kumar, Vincent B. Tucci
  • Publication number: 20120263797
    Abstract: A solidifying prepolymeric implant composition comprising a biocompatible prepolymer and an optional filler. One such implant composition is a polyurethane implant composition comprising an isocyanate, such as hydroxymethylenediisocyanate (HMDI) and an alcohol, such as polycaprolactonediol (PCL diol). The compositions of the invention are useful for improving bone structure in patients by applying the solidifying implant composition to bone, reinforcing bone structure, improving load bearing capacity and/or aiding healing of microfractures.
    Type: Application
    Filed: April 20, 2012
    Publication date: October 18, 2012
    Applicant: BIOS2 Medical, Inc.
    Inventors: Jeffrey A. D'Agostino, Andrew J. Carter, Craig M. Jones, Arthur C. Watterson
  • Publication number: 20120100583
    Abstract: The invention relates to new methods of enzymatic synthesis of polymers such as polyorganosilicones and polyesters, and new polymers made by these methods.
    Type: Application
    Filed: May 24, 2011
    Publication date: April 26, 2012
    Applicant: UNIVERSITY OF MASSACHUSETTS
    Inventors: Rajesh Kumar, Arthur C. Watterson, Virinder Singh Parmar, Jayant Kumar, Lynne Ann Samuelson
  • Publication number: 20110136958
    Abstract: A polymer is characterized by a repeat unit represented by Structural Formula (I), or a copolymer thereof. A crosslinked polymer characterized by a repeat unit represented by Structural Formula (II), (III), (IV) or (V), or a copolymer thereof, wherein at least one such repeat unit of a first polymer strand is crosslinked with at least one repeat unit of a second polymer strand by at least one bridging unit, the first and second polymer strands and the repeat unit being components of the crosslinked polymer.
    Type: Application
    Filed: September 10, 2008
    Publication date: June 9, 2011
    Inventors: Arthur C. Watterson, Ravi Mosurkal, Jayant Kumar, Virinder S. Parmar, Lynne A. Samuelson, Rajesh Kumar, Vincent Tucci
  • Publication number: 20100310647
    Abstract: The invention relates to new methods of enzymatic synthesis of polymers such as polyorganosilicones and polyesters, and new polymers made by these methods.
    Type: Application
    Filed: May 5, 2010
    Publication date: December 9, 2010
    Applicant: UNIVERSITY OF MASSACHUSETTS
    Inventors: Rajesh Kumar, Arthur C. Watterson, Virinder Singh Parmar, Jayant Kumar, Lynne Ann Samuelson
  • Publication number: 20090099267
    Abstract: Polymers having a main chain having both aromatic units and aliphatic units (with repeating heteroatoms) and a side chain macromonomer are described. Methods of making these polymers using enzymatic synthesis and the applications of these polymers are also described.
    Type: Application
    Filed: May 26, 2006
    Publication date: April 16, 2009
    Applicant: University of Massachusetts
    Inventors: Rajesh Kumar, Jayant Kumar, Virinder Singh Parmar, Arthur C. Watterson
  • Patent number: 6962963
    Abstract: The invention relates to new methods of enzymatic synthesis of polymers such as polyorganosilicones and polyesters, and new polymers made by these methods.
    Type: Grant
    Filed: October 17, 2003
    Date of Patent: November 8, 2005
    Assignee: University of Massachusetts
    Inventors: Rajesh Kumar, Arthur C. Watterson, Virinder Singh Parmar, Jayant Kumar, Lynne Ann Samuelson
  • Publication number: 20040152176
    Abstract: The invention relates to new methods of enzymatic synthesis of polymers such as polyorganosilicones and polyesters, and new polymers made by these methods.
    Type: Application
    Filed: October 17, 2003
    Publication date: August 5, 2004
    Inventors: Rajesh Kumar, Arthur C. Watterson, Virinder Singh Parmar, Jayant Kumar, Lynne Ann Samuelson
  • Publication number: 20030144458
    Abstract: The invention is based in part on the discovery of polymers that can complex with certain types of therapeutic drugs and transport those drugs across cell membranes in cell cultures with demonstrable therapeutic activity. The polymers are designed to overcome some of the known problems of liposomes as drug carriers. The polymers can be used in the development of physiologically stable, non-leaking, non-immunogenic, efficacious and safe targetable drug delivery systems (e.g., for delivery of anti-HIV or anticancer drugs).
    Type: Application
    Filed: January 27, 2003
    Publication date: July 31, 2003
    Applicant: University of Massachusetts, a Massachusetts corporation
    Inventors: Arthur C. Watterson, Kunya Danprasert, Anil Diwan
  • Patent number: 6521736
    Abstract: The invention is based in part on the discovery of polymers that can complex with certain types of therapeutic drugs and transport those drugs across cell membranes in cell cultures with demonstrable therapeutic activity. The polymers are designed to overcome some of the known problems of liposomes as drug carriers. The polymers can be used in the development of physiologically stable, non-leaking, non-immunogenic, efficacious and safe targetable drug delivery systems (e.g., for delivery of anti-HIV or anticancer drugs).
    Type: Grant
    Filed: September 14, 2001
    Date of Patent: February 18, 2003
    Assignee: University of Massachusetts
    Inventors: Arthur C. Watterson, Kunya Danprasert, Anil Diwan
  • Publication number: 20020099164
    Abstract: The invention is based in part on the discovery of polymers that can complex with certain types of therapeutic drugs and transport those drugs across cell membranes in cell cultures with demonstrable therapeutic activity. The polymers are designed to overcome some of the known problems of liposomes as drug carriers. The polymers can be used in the development of physiologically stable, non-leaking, non-immunogenic, efficacious and safe targetable drug delivery systems (e.g., for delivery of anti-HIV or anticancer drugs).
    Type: Application
    Filed: September 14, 2001
    Publication date: July 25, 2002
    Inventors: Arthur C. Watterson, Kunya Danprasert, Anil Diwan