Patents by Inventor Arthur D. Strosberg

Arthur D. Strosberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for preparing rabbit monoclonal antibodies, the cell lines used therein and the antibodies produced thereby
    Patent number: 4859595
    Abstract: A new continuous rabbit cell line, designated TP-3, and variants thereof, which are hypoxyxanthineguanine-phosphoribosyl transferase deficient, hypoxyxanthine-aminopterine-thymidine sensitive, fast growing and non-antibody producing, and the methods for preparing the TP-3 cell line. Also, rabbit-rabbit hybrid cells formed by fusing the TP-3 cell line with antibody-producing cells from immunized rabbits, which hybrid cells are hypoxyxanthine-aminopterine-thymidine insensitve and secrete rabbit antibodies, and the methods for preparing the hybrid cells and hybrid cell lines. The invention further comprises rabbit monoclonal antibody.
    Type: Grant
    Filed: May 3, 1985
    Date of Patent: August 22, 1989
    Inventors: Arthur D. Strosberg, Jean-Gerard Guillet
  • Monoclonal antibodies to legionella, a process for their preparation and their use in the determination of legionella pneumophila
    Patent number: 4780407
    Abstract: A process to produce hybrid cell lines, which produce monoclonal antibodies to Legionella pneumophila. Cell lines are produced by fusion of immunized mouse splenocytes to these bacteria with non secreting myeloma cells.Monoclonal antibodies are useful for diagnosis of diseases due to Legionella pneumophilia, for detection of these bacteria in environment, for the production of vaccines.
    Type: Grant
    Filed: July 1, 1987
    Date of Patent: October 25, 1988
    Assignees: Institut Pasteur, Centre National de la Recherche Scientifique
    Inventors: Arthur D. Strosberg, Jean G. Guillet, Johan Hoebeke, Cuong Tram