Abstract: The subject invention pertains to the therapeutic use of certain GAG-degrading enzymes, and enzyme combinations, to promote nerve repair and regeneration.

Abstract: A platform independent model for exchanging information among numerous entities in a justice system with diverse system components is implemented in a hub and spoke arrangement. Each spoke includes a software agent that communicates with a system component of an entity of the justice system, translates from a common communication format to a communication format of the system component, and manages the timing of the flow of information to/from the system component. The hub includes an information broker that communicates with each agent in the common communication format, determines what information is needed by which entity, and routes the needed information to/from respective agents for the entities that need the information. The platform independent model includes a plurality of traceable and linked UML models that define the information broker from a business use case model through to a platform independent solution model for implementation on a given solution platform.