Patents by Inventor Arthur Glenn Romero

Arthur Glenn Romero has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tricyclic tetrahydroquinoline antibacterial agents
    Patent number: 7605157
    Abstract: The invention includes tetrahydroquinoline and related compounds of formula I and pharmaceutical compositions thereof, that exhibit useful antibacterial activity again a wide range of human and veterinary pathogens
    Type: Grant
    Filed: March 7, 2007
    Date of Patent: October 20, 2009
    Assignee: Pharmacia & Upjohn Company LLC
    Inventors: Michael Robert Barbachyn, J. Craig Ruble, Arthur Glenn Romero, Lisa Marie Thomasco, Alexander Ross Hurd, John Raymond Palmer, Peter Laurence Toogood, Dennis Joseph McNamara, Debra Ann Sherry, Paul Joseph Dobrowolski
  • Tricyclic tetrahydroquinoline antibacterial agents
    Patent number: 7208490
    Abstract: The invention includes tetrahydroquinoline and related compounds of formula I, and pharmaceutical compositions thereof, that exhibit useful antibacterial activity against a wide range of human and veterinary pathogens
    Type: Grant
    Filed: October 2, 2003
    Date of Patent: April 24, 2007
    Assignee: Pharmacia & Upjohn Company LLC
    Inventors: Michael Robert Barbachyn, Gordan L. Bundy, Paul Joseph Dobrowolski, Alexander Ross Hurd, Gary E. Martin, Dennis Joseph McNamara, John Raymond Palmer, Donna L. Romero, Arthur Glenn Romero, J. Craig Ruble, Debra Ann Sherry, Lisa Marie Thomasco, Peter Laurence Toogood
  • Hydroxy alkyl amines
    Patent number: 7144897
    Abstract: Disclosed are compounds of formula X, which are useful in treating Alzheimer's disease and other similar diseases. Pharmaceutical compositions comprising compounds of formula X and methods of preparing the compounds of formula X are also disclosed.
    Type: Grant
    Filed: May 31, 2002
    Date of Patent: December 5, 2006
    Assignees: Elan Oharmaceuticals, Inc., Pharmacia & Upjohn, Co.
    Inventors: John Freskos, David L. Brown, Yvette M. Fobian, Larry Fang, Arthur Glenn Romero, Varghese John
  • Indoles and indolines having 5-HT activity
    Patent number: 7022694
    Abstract: The present invention provides compounds of Formula (I): wherein R1, R2, R3, R4, R5, R6 and --- have any of the values defined in the specification, as well as pharmaceutical compositions comprising the compounds. The invention also provides therapeutic methods as well as processes and intermediates useful for preparing compounds of Formula (I). The compounds are useful as 5-HT ligands.
    Type: Grant
    Filed: July 11, 2002
    Date of Patent: April 4, 2006
    Assignee: Pharmacia & UpJohn Company
    Inventors: Jian-Min Fu, Jeanette Kay Morris, Arthur Glenn Romero
  • Process to prepare 2-aminoindan derivatives
    Patent number: 6870070
    Abstract: The present invention relates to (2S)-enantiomers of 2-aminoindan derivatives of formula I: and a novel process for the preparation of them.
    Type: Grant
    Filed: April 29, 2002
    Date of Patent: March 22, 2005
    Assignee: Pharmacia & Upjohn Company
    Inventors: Arthur Glenn Romero, Thomas Andrew Runge, Bradley D. Hewitt, Kjell Anders Ivan Svensson, Chiu-Hong Lin, Kerry Anne Cleek, Susanne R. Haadsma-Svensson
  • Tricyclic tetrahydroquinoline antibacterial agents
    Publication number: 20040162279
    Abstract: The invention includes tetrahydroquinoline and related compounds of formula I, and pharmaceutical compositions thereof, that exhibit useful antibacterial activity against a wide range of human and veterinary pathogens.
    Type: Application
    Filed: October 2, 2003
    Publication date: August 19, 2004
    Inventors: Michael Robert Barbachyn, J. Craig Ruble, Arthur Glenn Romero, Lisa Marie Thomasco, Alexander Ross Hurd, John Raymond Palmer, Peter Laurence Toogood, Dennis Joseph McNamara, Debra Ann Sherry, Paul Joseph Dobrowolski
  • Hydroxy alkyl amines
    Publication number: 20030166717
    Abstract: Disclosed are compounds of formula X, 1
    Type: Application
    Filed: May 31, 2002
    Publication date: September 4, 2003
    Inventors: John Freskos, David L. Brown, Yvette M. Fobian, Larry Fang, Arthur Glenn Romero, Varghese John
  • Process to prepare (2S)-2-(dipropylamino)-6-ethoxy-2,3-dihydro-1H-indene-5-carboxamide
    Patent number: 6576769
    Abstract: The present invention is a process, including intermediates, to produce (2S)-2-dipropylamino)-6-ethoxy-2,3-dihydro-1H-indene-5-carboxamide which is a useful pharmaceutical agent.
    Type: Grant
    Filed: June 6, 2002
    Date of Patent: June 10, 2003
    Assignee: Pharmacia & Upjohn Company
    Inventors: Jiong Jack Chen, Arthur Glenn Romero, Styrbjorn Bystrom
  • Indoles and indolines having 5-HT activity
    Publication number: 20030060458
    Abstract: The present invention provides compounds of Formula (I): 1
    Type: Application
    Filed: July 11, 2002
    Publication date: March 27, 2003
    Inventors: Jian-Min Fu, Jeanette Kay Morris, Arthur Glenn Romero
  • Heterocyclic amines having central nervous system activity
    Publication number: 20020187981
    Abstract: Tricyclic nitrogen containing compounds, having anxiolytic and anti-depressant activity and central nervous system activity of the following structural formula: 1
    Type: Application
    Filed: April 5, 2002
    Publication date: December 12, 2002
    Inventor: Arthur Glenn Romero
  • Process to prepare (2S)-2-(dipropylamino)-6-ethoxy-2,3-dihydro-1H-indene-5-carboxamide
    Publication number: 20020151750
    Abstract: The present invention is a process, including intermediates, to produce (2S)-2-dipropylamino)-6 -ethoxy-2,3-dihydro-1H-indene-5-carboxarnide 1
    Type: Application
    Filed: June 6, 2002
    Publication date: October 17, 2002
    Inventors: Jiong Jack Chen, Arthur Glenn Romero, Styrbjorn Bystrom
  • Novel process to prepare 2-aminoindan derivatives
    Publication number: 20020151596
    Abstract: The present invention relates to (2S)-enantiomers of 2-aminoindan derivatives of formula I: 1
    Type: Application
    Filed: April 29, 2002
    Publication date: October 17, 2002
    Inventors: Arthur Glenn Romero, Thomas Andrew Runge, Bradley D. Hewitt, Kjell Anders Ivan Svensson, Chiu-Hong Lin, Kerry Anne Cleek, Susanne R. Haadsma-Svensson
  • Process to prepare (2S)-2-(dipropylamino)-6-ethoxy-2, 3-dihydro-1H-indene-5-carboxamide
    Patent number: 6462234
    Abstract: The present invention is a process, including intermediates, to produce (2S)-2-dipropylamino)-6-ethoxy-2,3-dihydro-1H-indene-5-carboxamide which is a useful pharmaceutical agent.
    Type: Grant
    Filed: September 14, 2001
    Date of Patent: October 8, 2002
    Assignee: Pharmacia & Upjohn Company
    Inventors: Jiong Jack Chen, Arthur Glenn Romero, Styrbjorn Bystrom
  • Process to prepare (2S)-2-(dipropylamino)-6-ethoxy-2,3-dihydro-1H-indene-5-carboxamide
    Publication number: 20020107418
    Abstract: The present invention is a process, including intermediates, to produce (2S)-2-dipropylamino)-6-ethoxy-2,3-dihydro-1H-indene-5-carboxamide 1
    Type: Application
    Filed: September 14, 2001
    Publication date: August 8, 2002
    Inventors: Jiong Jack Chen, Arthur Glenn Romero, Styrbjorn Bystrom
  • Process to prepare 2-aminoindan derivatives
    Patent number: 6410787
    Abstract: The present invention relates to (2S)-enantiomers of 2-aminoindan derivatives of formula I: and a novel process for the preparation of them.
    Type: Grant
    Filed: February 14, 2001
    Date of Patent: June 25, 2002
    Assignee: Pharmacia & Upjohn Company
    Inventors: Arthur Glenn Romero, Thomas Andrew Runge, Bradley D. Hewitt, Kjell Anders Ivan Svensson, Chiu-Hong Lin, Kerry Anne Cleek, Susanne R. Haadsma-Svensson
  • Novel process to prepare 2-aminoindan derivatives
    Publication number: 20010044471
    Abstract: The present invention relates to (2S)-enantiomers of 2-aminoindan derivatives of formula I: 1
    Type: Application
    Filed: February 14, 2001
    Publication date: November 22, 2001
    Inventors: Arthur Glenn Romero, Thomas Andrew Runge, Bradley D. Hewitt, Kjell Anders Ivan Svensson, Chiu-Hong Lin, Kerry Anne Cleek, Susanne R. Haadsma-Svensson
  • 8-hydroxy-7-substituted quinolines as anti-viral agents
    Patent number: 6310211
    Abstract: The present invention provides for 8-hydroxy-7-substituted quinoline compounds such as formula IA These compounds are useful as anti-viral agents. Specifically, these compounds have anti-viral activity against the herpes virus, cytomegalovirus (CMV). Many of these compounds are also active against other herpes viruses, such as the varicella zoster virus, the Epstein-Barr virus, the herpes simplex virus and the human herpes virus type 8 (HHV-8).
    Type: Grant
    Filed: September 5, 1997
    Date of Patent: October 30, 2001
    Assignee: Pharmacia & Upjohn Company
    Inventors: Valerie Ann Vaillancourt, Karen Rene Romines, Arthur Glenn Romero, John Alan Tucker, Joseph Walter Strohbach, Olivier Bezencon, Suvit Thaisrivongs
  • 8-hydroxy-7-substituted quinolines as anti-viral agents
    Patent number: 6211376
    Abstract: The present invention provides for 8-hydroxy-7-substituted quinoline compounds such as formula III These compounds are useful as anti-viral agents. Specifically, these compounds have anti-viral activity against the herpes virus, cytomegalovirus (CMV). Many of these compounds are also active against other herpes viruses, such as the varicella zoster virus, the Epstein-Barr virus, the herpes simplex virus and the human herpes virus type 8 (HHV-8).
    Type: Grant
    Filed: October 22, 1999
    Date of Patent: April 3, 2001
    Assignee: Pharmacia & Upjohn Company
    Inventors: Karen Rene Romines, John Alan Tucker, Arthur Glenn Romero
  • Phenylsulfonamide-phenylethylamines useful as dopamine receptors
    Patent number: 6103766
    Abstract: Compounds of Formula I and their pharmaceutically acceptable salts having selective dopamine D3 receptor activity suitable for treating central nervous system disorders. Formula I: ##STR1## R.sub.1 is independently H or a C.sub.1 -C.sub.8 alkyl including isomeric forms thereof;R.sub.2 is H, C.sub.1 -C.sub.3 alkyl, a halogen, OCH.sub.3 , OCF.sub.3, CF.sub.3, CN, SCH.sub.3 or NHCOCH.sub.3 ; andR.sub.3 is H, C.sub.1 -C.sub.3 alkyl, a halogen, OCH.sub.3 , OCF.sub.3, CF.sub.3, CN, SCH.sub.3 or NHCOCH.sub.3.
    Type: Grant
    Filed: May 7, 1999
    Date of Patent: August 15, 2000
    Assignee: Pharmacia & Upjohn Company
    Inventors: Arthur Glenn Romero, Jeffrey A. Leiby
  • Heterocyclic amines having central nervous system activity
    Patent number: RE38452
    Abstract: Tricyclic nitrogen containing compounds, having anxiolytic and anti-depressant activity and central nervous system activity of the following structural formula: and pharmaceutically acceptable salts thereof wherein R1 and R2 are independently hydrogen, C1-6 alkyl or R1 and R2 are joined to form pyrrolidine, piperidine, morpholine or imidazole. X is OCH3, SO2R3, SO2CF3 or CN where R3 is C1-6 alkyl or an Aryl; and Y is hydrogen, Cl, Br, F, CN, CONR1R2, CF3, OCH3, SO2NR1R2. These new compounds are suitable for treating anxiolytic disorder, schizophrenia, Parkinson's disease, anxiety, depression or as compounds for lowering blood pressure or treating migraine headaches in patients in need of such treatment.
    Type: Grant
    Filed: May 13, 1999
    Date of Patent: March 2, 2004
    Assignee: Pharmacia & Upjohn Company
    Inventor: Arthur Glenn Romero