Patents by Inventor Arthur H. Reis, JR.

Arthur H. Reis, JR. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • REAGENTS FOR IMPROVING PCR ACCURACY
    Publication number: 20220090216
    Abstract: Provided herein are reagents for improving PCR accuracy.
    Type: Application
    Filed: September 28, 2021
    Publication date: March 24, 2022
    Inventors: John RICE, Lawrence WANGH, Arthur H. REIS, JR., Kenneth PIERCE, Cristina HARTSHORN, J. Aquiles SANCHEZ, Stephen VAN HOOSER, Skye FISHBEIN
  • Reagents for improving PCR accuracy
    Patent number: 11162146
    Abstract: Provided herein are reagents for improving PCR accuracy.
    Type: Grant
    Filed: April 1, 2019
    Date of Patent: November 2, 2021
    Assignee: Brandeis University
    Inventors: John Rice, Lawrence Wangh, Arthur H. Reis, Jr., Kenneth Pierce, Cristina Hartshorn, J. Aquiles Sanchez, Stephen Van Hooser, Skye Fishbein
  • Kits and reaction mixtures for analyzing single-stranded nucleic acid sequences
    Patent number: 10570462
    Abstract: Provided herein are kits for performing for nucleic acid sequences.
    Type: Grant
    Filed: May 27, 2016
    Date of Patent: February 25, 2020
    Assignee: Brandeis University
    Inventors: Lawrence J. Wangh, John E. Rice, J. Aquiles Sanchez, Arthur H. Reis, Jr.
  • REAGENTS FOR IMPROVING PCR ACCURACY
    Publication number: 20190292610
    Abstract: Provided herein are reagents for improving PCR accuracy.
    Type: Application
    Filed: April 1, 2019
    Publication date: September 26, 2019
    Inventors: John RICE, Lawrence Wangh, Arthur H. Reis, JR., Kenneth Pierce, Cristina Hartshorn, J. Aquiles Sanchez, Stephen Van Hooser, Skye Fishbein
  • Reagents for improving PCR accuracy
    Patent number: 10301688
    Abstract: Provided herein are reagents for improving PCR accuracy.
    Type: Grant
    Filed: January 23, 2014
    Date of Patent: May 28, 2019
    Assignee: BRANDEIS UNIVERSITY
    Inventors: John Rice, Lawrence Wangh, Arthur H. Reis, Jr., Kenneth Pierce, Cristina Hartshorn, J. Acquiles Sanchez, Stephen Van Hooser, Skye Fishbein
  • Single probe, multiple temperature, nucleic acid detection methods, kits, and compositions
    Patent number: 9493835
    Abstract: Provided herein are methods, kits, and compositions related to nucleic acid detection assays that allow discrimination of multiple target sequences with a single probe. In particular, provided herein are methods kits, and compositions that include single-probe target sequence discrimination where different target amplicons may have identical probe hybridization sequences by employing multiple temperature end-point signal probe detection. Also provided herein are methods, kits, and compositions for distinguishing between two or more target amplicons using multiple-temperature end-point probe detection. In certain embodiments, asymmetric PCR amplification methods are employed (e.g., LATE-PCR amplification).
    Type: Grant
    Filed: August 11, 2010
    Date of Patent: November 15, 2016
    Assignee: Brandeis University
    Inventors: Arthur H. Reis, Jr., Lawrence J. Wangh, Kenneth Pierce
  • Kits and Reaction Mixtures for Analyzing Single-Stranded Nucleic Acid Sequences
    Publication number: 20160258001
    Abstract: Provided herein are kits for performing for nucleic acid sequences.
    Type: Application
    Filed: May 27, 2016
    Publication date: September 8, 2016
    Inventors: Lawrence J. Wangh, John E. Rice, J. Aquiles Sanchez, Arthur H. Reis, JR.
  • detection assays
    Patent number: 9376723
    Abstract: Provided herein are methods, kits, and compositions related to nucleic acid detection that allow the detection and discrimination of various Staphylococcus species and types. In particular, provided herein are assays that allow the detection of MSSA, MSSE, MRSA, MRSE, VRSA, VRSE, and MRSA community strain by detecting the presence of absence of one or more target sequences selected from a list of target genes and sequences that include, but are not limited to: mecA, femA-SA, femA-SE, lukF-PV, lukS-PV, VanA, SCCmec type I, type II, type III, type IV, type V, and type VII. In certain embodiments, asymmetric PCR amplification methods are employed. In other embodiments, probe-target generated signals are detected at least two temperatures to generate a temperature/temperature signal ratio.
    Type: Grant
    Filed: August 11, 2010
    Date of Patent: June 28, 2016
    Assignee: Brandeis University
    Inventors: Arthur H. Reis, Jr., Lawrence J. Wangh, Kenneth Pierce
  • REAGENTS FOR IMPROVING PCR ACCURACY
    Publication number: 20140206564
    Abstract: Provided herein are reagents for improving PCR accuracy.
    Type: Application
    Filed: January 23, 2014
    Publication date: July 24, 2014
    Applicant: Brandeis University
    Inventors: John Rice, Lawrence Wangh, Arthur H. Reis, JR., Kenneth Pierce, Cristina Hartshorn, J. Aquiles Sanchez, Stephen Van Hooser, Skye Fishbein
  • STAPHYLOCOCCUS DETECTION ASSAYS
    Publication number: 20120208191
    Abstract: Provided herein are methods, kits, and compositions related to nucleic acid detection that allow the detection and discrimination of various Staphylococcus species and types. In particular, provided herein are assays that allow the detection of MSSA, MSSE, MRSA, MRSE, VRSA, VRSE, and MRSA community strain by detecting the presence of absence of one or more target sequences selected from a list of target genes and sequences that include, but are not limited to: mecA, femA-SA, femA-SE, lukF-PV, lukS-PV, VanA, SCCmec type I, type II, type III, type IV, type V, and type VII. In certain embodiments, asymmetric PCR amplification methods are employed. In other embodiments, probe-target generated signals are detected at least two temperatures to generate a temperature/temperature signal ratio.
    Type: Application
    Filed: August 11, 2010
    Publication date: August 16, 2012
    Applicant: Brandeis University
    Inventors: Arthur H. Reis, JR., Lawrence J. Wangh, Kenneth Pierce
  • SINGLE PROBE, MULTIPLE TEMPERATURE, NUCLEIC ACID DETECTION METHODS, KITS, AND COMPOSITIONS
    Publication number: 20120202203
    Abstract: Provided herein are methods, kits, and compositions related to nucleic acid detection assays that allow discrimination of multiple target sequences with a single probe. In particular, provided herein are methods kits, and compositions that include single-probe target sequence discrimination where different target amplicons may have identical probe hybridization sequences by employing multiple temperature end-point signal probe detection. Also provided herein are methods, kits, and compositions for distinguishing between two or more target amplicons using multiple-temperature end-point probe detection. In certain embodiments, asymmetric PCR amplification methods are employed (e.g., LATE-PCR amplification).
    Type: Application
    Filed: August 11, 2010
    Publication date: August 9, 2012
    Applicant: BRANDEIS UNIVERSITY
    Inventors: Arthur H. Reis, JR., Lawrence J. Wangh, Kenneth Pierce