Abstract: The present invention, referred to as Oasis is Automated Statistical Inference for Segmentation (OASIS), is a fully automated and robust statistical method for cross-sectional MS lesion segmentation. Using intensity information from multiple modalities of MRI, a logistic regression model assigns voxel-level probabilities of lesion presence. The OASIS model produces interpretable results in the form of regression coefficients that can be applied to imaging studies quickly and easily. OASIS uses intensity-normalized brain MRI volumes, enabling the model to be robust to changes in scanner and acquisition sequence. OASIS also adjusts for intensity inhomogeneities that preprocessing bias field correction procedures do not remove, using BLUR volumes. This allows for more accurate segmentation of brain areas that are highly distorted by inhomogeneities, such as the cerebellum.

Abstract: The present invention, referred to as Oasis is Automated Statistical Inference for Segmentation (OASIS), is a fully automated and robust statistical method for cross-sectional MS lesion segmentation. Using intensity information from multiple modalities of MRI, a logistic regression model assigns voxel-level probabilities of lesion presence. The OASIS model produces interpretable results in the form of regression coefficients that can be applied to imaging studies quickly and easily. OASIS uses intensity-normalized brain MRI volumes, enabling the model to be robust to changes in scanner and acquisition sequence. OASIS also adjusts for intensity inhomogeneities that preprocessing bias field correction procedures do not remove, using BLUR volumes. This allows for more accurate segmentation of brain areas that are highly distorted by inhomogeneities, such as the cerebellum.

Abstract: A tackle box has a box body with a hinged lid. The box body has a deeper front portion and a shallower back portion. Correspondingly, the lid has a deeper back portion and shallower front portion. The back portion of the box body carries a stack of interconnected slidably mounted superimposed trays which can be pulled out rearwardly cantilever fashion when the lid is opened. The front portion of the box body has superimposed pull-out drawers. The box has a bail-type pivoting handle with a lid-latching mechanism which only allows the lid to open when the handle is swung forward from a box-carrying position. In the top of the lid, there is a removable shallow carrying case which can be used separately from the box.