Abstract: For particle separation, a method and apparatus for using a wide angle radially expanding vapor of a particle mixture. In particular, selective ionization of one isotope type in the particle mixture is produced in a multichamber separator and the ionized isotope type is accelerated out of the path of the vapor expansion for separate collection.FIELD OF THE INVENTIONThis invention relates to isotope separation by selective ionization and in particular to a separation system making efficient use of an isotope source.BACKGROUND OF THE INVENTIONNearly all fission reactions utilizing the uranium isotope, U.sub.235, require a concentration of the U.sub.235 isotope greater than in the naturally occurring state. The process of enrichment whereby the concentration of U.sub.235 in natural or depleted uranium is raised to a desired level has been achieved in the past by many techniques which generally operate to separate U.sub.235 from the other uranium isotopes, chiefly U.sub.