Patents by Inventor Arthur Kluge

Arthur Kluge has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of identifying inhibitors of CDC25
    Publication number: 20020183249
    Abstract: The present invention relates to polypeptides which comprise the ligand binding domain of Cdc25, crystalline forms of these polypeptides and the use of these crystalline forms to determine the three dimensional structure of the catalytic domain of Cdc25. The invention also relates to the use of the three dimensional structure of the Cdc25 catalytic domain in methods of designing and/or identifying potential inhibitors of Cdc25 activity, for example, compounds which inhibit the binding of a native substrate to the Cdc25 catalytic domain.
    Type: Application
    Filed: March 1, 2001
    Publication date: December 5, 2002
    Inventors: Neil R. Taylor, David Borhani, David Epstein, Johannes Rudolph, Kurt Ritter, Taro Fujimori, Simon Robinson, Jens Eckstein, Andreas Haupt, Nigel Walker, Richard W. Dixon, Deborah Choquette, Jill Blanchard, Arthur Kluge, Kollol Pal, Nicholas Bockovich, Jon Come, Mark Hediger
  • Compositions and methods for inhibiting fungal growth
    Patent number: 6423519
    Abstract: The present invention relates to compositions and methods for inhibiting fungal growth. In particular, the present invention relates to methods for use as anti-fungal agents of inhibitors, and compositions thereof, of fungal GGPTase. The inhibitors of fungal GGPTase may be peptides, peptidomimetics, or non-peptides.
    Type: Grant
    Filed: October 15, 1998
    Date of Patent: July 23, 2002
    Assignee: GPC Biotech Inc.
    Inventors: Gustave Bergnes, Vivian Berlin, Jon Come, Arthur Kluge, Krishna Murthi, Kollol Pal