Abstract: This invention is directed to methods for treating hyperhidrosis in mammals. Specifically, the methods of this invention involve the topical administration of glycopyrrolate compounds to humans.

Abstract: This invention is directed to methods for treating hot flashes as a consequence of declining levels of estrogen or androgen in humans. Specifically, the methods of this invention involve the topical administration of a glycopyrrolate analog of Formula (I) to humans.

Abstract: This invention is directed to methods for treating hot flashes as a consequence of declining levels of estrogen or androgen in humans. Specifically, the methods of this invention involve the topical administration of glycopyrrolate compounds to humans.

Abstract: A hypodermic needle assembly is described which automatically covers the pointed end of the needle after the assembly is used in order to prevent accidental punctures. A sheath circumscribes the needle and is held a patient's tissue to allow sliding movement of the sheath over the needle pointed end, and preferably locking of the needle within the sheath, as well, when the needle is withdrawn from the patient.

Abstract: Various embodiments of a simple hypodermic needle assembly are described designed to automatically cover the pointed end of the needle after the assembly is used in order to prevent accidental punctures. A sheath circumscribes the needle and includes barbs for interacting with a patient's tissue to cause sliding movement of the sheath over the needle pointed end when the needle is withdrawn from the patient. When the needle pointed end is covered, the barbs automatically withdraw and permit the needle sheath combination to be completely withdrawn from the patient.

Abstract: A lockable closure for containers that is held in the locked condition regardless of the orientation of the container, yet is easily releasable in order to permit opening by simple techniques. The closure includes an internal housing in which a vertically movable locking member is retained, and from which a plurality of locking pins radially extend. The neck around the container opening includes pairs of opposed recesses to receive the locking pins when the locking member is in its lowered locking position. Raising of the locking member and release of the lock is accomplished by use of an exteriorly applied magnet that will attract the locking member and raise it out of engagement with the locking recesses in the container neck.