Patents by Inventor Arthur Michaelis

Arthur Michaelis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical compositions and uses thereof
    Publication number: 20070248668
    Abstract: The invention features pharmaceutical compositions including rifalazil, a surfactant, and a lipophilic antioxidant and methods of use thereof.
    Type: Application
    Filed: April 5, 2007
    Publication date: October 25, 2007
    Inventors: Arthur Michaelis, Panayiotis Constantinides
  • Rifamycin analogs and uses thereof
    Publication number: 20070238747
    Abstract: The present invention features rifamycin analogs that can be used as therapeutics for treating or preventing a variety of microbial infections. In one form, the analogs are acetylated at the 25-position, as is rifamycin. In another form, the analogs are deacetylated at the 25-position. In yet other forms, benzoxazinorifamycin, benzthiazinorifamycin, and benzdiazinorifamycin analogs are derivatized at various positions of the benzene ring, including 3?-hydroxy analogs, and/or various fused ring systems with the benzene ring at the 4?,5? or 5?,6? positions.
    Type: Application
    Filed: May 17, 2007
    Publication date: October 11, 2007
    Applicant: ActivBiotics, Inc.
    Inventors: John van Duzer, Arthur Michaelis, William Geiss, Douglas Stafford, Xiang Yu, James Siedlecki, Yingfei Yang
  • Rifamycin analogs and uses thereof
    Publication number: 20070155715
    Abstract: The present invention features rifamycin analogs and methods of using these compounds to treat a variety of microbial infections.
    Type: Application
    Filed: December 14, 2006
    Publication date: July 5, 2007
    Applicant: ActivBiotics, Inc.
    Inventors: John van Duzer, Arthur Michaelis, William Geiss, Douglas Stafford, Joseph Raker, Xiang Yu, James Siedlecki, Yingfei Yang
  • Rifamycin analogs and uses thereof
    Publication number: 20050197333
    Abstract: The present invention features rifamycin analogs that can be used as therapeutics for treating or preventing a variety of microbial infections. In one form, the analogs are acetylated at the 25-position, as is rifamycin. In another form, the analogs are deacetylated at the 25-position. In yet other forms, benzoxazinorifamycin, benzthiazinorifamycin, and benzdiazinorifamycin analogs are derivatized at various positions of the benzene ring, including 3?-hydroxy analogs, 4?- and/or 6? halo and/or alkoxy analogs, and various 5? substituents that incorporate a cyclic amine moiety.
    Type: Application
    Filed: December 22, 2004
    Publication date: September 8, 2005
    Inventors: John van Duzer, Arthur Michaelis, William Geiss, Douglas Stafford, Joseph Raker, Xiang Yu, James Siedlecki, Yingfei Yang
  • Antimicrobial agents and uses thereof
    Publication number: 20050143374
    Abstract: The invention features compounds that act as antimicrobial agents and/or antimicrobial enhancer agents, compositions that include the antimicrobial enhancer agents of the invention, and methods for treating microbial infections using those compositions.
    Type: Application
    Filed: February 24, 2005
    Publication date: June 30, 2005
    Applicant: ActivBiotics, Inc.
    Inventors: Arthur Michaelis, Hawkins Maulding
  • Regimen for the administration of rifamycin-class antibiotics
    Publication number: 20050143409
    Abstract: The invention features an ascending dose regimen for the administration of rifamycin-class antibiotics. The dosing regimen can be used to treat bacterial infections and diseases related to infection.
    Type: Application
    Filed: September 23, 2004
    Publication date: June 30, 2005
    Inventors: Arthur Michaelis, Bernard Cabana
  • Rifamycin analogs and uses thereof
    Publication number: 20050137189
    Abstract: The present invention features rifamycin analogs that can be used as therapeutics for treating or preventing a variety of microbial infections. In one form, the analogs are acetylated at the 25-position, as is rifamycin. In another form, the analogs are deacetylated at the 25-position. In yet other forms, benzoxazinorifamycin, benzthiazinorifamycin, and benzdiazinorifamycin analogs are derivatized at various positions of the benzene ring, including 3?-hydroxy analogs, and/or various fused ring systems with the benzene ring at the 4?,5? or 5?,6? positions.
    Type: Application
    Filed: December 9, 2004
    Publication date: June 23, 2005
    Inventors: John van Duzer, Arthur Michaelis, William Geiss, Douglas Stafford, Xiang Yu, James Siedlecki, Yingfei Yang
  • Rifalazil formulations
    Publication number: 20050123602
    Abstract: The invention features pharmaceutical compositions including rifalazil and a micelle-forming excipient and methods of use thereof.
    Type: Application
    Filed: September 27, 2004
    Publication date: June 9, 2005
    Inventor: Arthur Michaelis
  • Rifamycin analogs and uses thereof
    Publication number: 20050043298
    Abstract: The present invention features rifamycin analogs that can be used as therapeutics for treating or preventing a variety of microbial infections. In one form, the analogs are acetylated at the 25-position, as is rifamycin. In another form, the analogs are deacetylated at the 25-position. In yet other forms, benzoxazinorifamycin, benzthiazinorifamycin, and benzdiazinorifamycin analogs are derivatized at various positions of the benzene ring, including 3?-hydroxy analogs, 4?-and/or 6? halo and/or alkoxy analogs, and various 5? substituents that incorporate a cyclic amine moiety.
    Type: Application
    Filed: August 11, 2004
    Publication date: February 24, 2005
    Inventors: John van Duzer, Arthur Michaelis, William Geiss, Douglas Stafford, Joseph Raker