Abstract: Methods, databases and software for determining the risk of an adverse health event for patient by analysis of the protein sequence of the patient are described. The methods involve obtaining a protein sequence that is associated with a specific disorder from the patient. The protein sequence from the patient is compared to a database of sequences of the same protein and is analyzed to determine the conservation score of the amino acid residues in the protein. Those amino acid residues having high conservation scores will be further analyzed to determine if there are mutations present at those highly conserved positions. Patients having proteins with mutations in highly conserved positions are determined to have a higher risk of an adverse event due to the disorder.

Abstract: Described is a method of determining the relative risk of an outcome based on an analysis of multiple risk factors. A graphical method is used to take values corresponding to risk parameters and an event outcome to produce a smoothed surface map representing relative risk over an entire space defined by n risk factors. Applying a query data point to the surface map permits the determination of the estimated outcome probability for the query data point, based on its location on the surface map. The method then reports a relative risk or other probability measure associated with the query data point. Also described is a method of analysis in which subpopulations previously identified as high-risk can be further analyzed with respect to risk posed by additional factors.

Abstract: A geosynthetic reinforcement comprising a container formed of semipermeable material mutually conformed with a portion of earthen material contained therein. A structural member such as a geogrid may engage (e.g. frictional) the container and extend therefrom to engage and support a structure such as a retaining wall, earthen slope, etc. Accordingly, the container may function as an anchor to the structure. Due to the containment provided by the container, the physical characteristics of the earthen material therewithin become less important. Thus, low quality fills such as fine-grained fill or fill with a high moisture content may be used in structural applications. If desired, more than one container and structural member may be incorporated. Containers may be stacked, positioned side-by-side, positioned end-to-end, etc. Structural members may be incorporated as needed to adequate support the structure. Drain layers may be incorporated to control moisture.

Abstract: A method for analyzing an ECG signal includes obtaining a measurement of an area based repolarization interval from at least one beat in the electrocardiogram signal and detecting an altered ventricular repolarization based on the obtained measured area based repolarization interval.

Abstract: A forearm developer having a cylindrical handle with a rope suspended from its center for attachment to a weight to raise same by twistingly rotating the handle. The handle is supported by a suspended frame having two depending parallel spaced apart support loops into which the opposing ends of the handle are placed for rotatable support.