Patents by Inventor Arthur Pichler

Arthur Pichler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystalline forms of tigecycline hydrochloride
    Patent number: 8252946
    Abstract: The present invention relates to crystalline forms A and B of Tigecycline hydrochloride and to methods for the preparation of the same. Furthermore the present invention relates to the use of crystalline forms A and B of Tigecycline hydrochloride as intermediates for the formulation of an anti-infective medicament. Moreover the present invention relates to pharmaceutical compositions comprising crystalline form A of Tigecycline hydrochloride in an effective amount and to the use of crystalline form A of Tigecycline hydrochloride as anti-infective medicament.
    Type: Grant
    Filed: November 12, 2008
    Date of Patent: August 28, 2012
    Assignee: Sandoz AG
    Inventors: Josef Wieser, Andreas Hotter, Arthur Pichler
  • CRYSTALLINE FORM OF POSACONAZOLE
    Publication number: 20120101277
    Abstract: The present invention relates to crystalline form II-S, its preparation and its use to prepare other crystalline forms of posaconazole, in particular crystalline form IV of posaconazole.
    Type: Application
    Filed: July 9, 2010
    Publication date: April 26, 2012
    Applicant: SANDOZ AG
    Inventors: Josef Wieser, Arthur Pichler, Andreas Hotter, Ulrich Griesser, Christoph Langes
  • CRYSTAL FORMS OF SAXAGLIPTIN
    Publication number: 20120088808
    Abstract: The present invention relates to novel polymorphic forms of Saxagliptin Hydrochloride. The present invention also relates to methods of making polymorphic forms of Saxagliptin Hydrochloride.
    Type: Application
    Filed: April 9, 2010
    Publication date: April 12, 2012
    Applicant: SANDOZ AG
    Inventors: Arthur Pichler, Josef Wieser, Christoph Langes, Milica Vukicevic
  • CRYSTALLINE FORM C OF TIGECYCLINE DIHYDROCHLORIDE AND METHODS FOR ITS PREPARATION
    Publication number: 20120022025
    Abstract: The present invention relates to crystalline form C of Tigecycline dihydrochloride and to methods for the preparation of the same. Furthermore the present invention relates to the use of crystalline form C of Tigecycline dihydrochloride as an intermediate for the preparation of an anti-infective medicament. Moreover the present invention relates to pharmaceutical compositions comprising crystalline form C of Tigecycline dihydrochloride in an effective amount and to the use of crystalline form C of Tigecycline dihydrochloride as an anti-infective medicament.
    Type: Application
    Filed: December 18, 2009
    Publication date: January 26, 2012
    Applicant: SANDOZ AG
    Inventors: Andreas Hotter, Josef Wieser, Arthur Pichler, Martin Decristoforo
  • ANTIBIOTIC COMPOUNDS
    Publication number: 20110124893
    Abstract: The present invention relates to the new crystalline solid form XI of Tigecycline and a process of preparing the same. Form XI of Tigecycline is particularly suitable for the isolation of Tigecycline in the last step of the synthesis of Tigecycline. Further the present invention relates to a process of preparing amorphous Tigecycline by spray drying form XI or another crystalline form of Tigecycline.
    Type: Application
    Filed: January 19, 2009
    Publication date: May 26, 2011
    Applicant: SANDOZ AG
    Inventors: Martin Decristoforo, Josef Wieser, Arthur Pichler, Andreas Hotter
  • PHARMACEUTICAL COMPOSITIONS CONTAINING A CRYSTALLINE FORM OF POSACONAZOLE
    Publication number: 20110105525
    Abstract: The present invention relates to a pharmaceutical composition comprising crystalline form Y of posaconazole. The pharmaceutical composition can be used to treat or prevent fungal infections.
    Type: Application
    Filed: May 28, 2009
    Publication date: May 5, 2011
    Applicant: SANDOZ AG
    Inventors: Josef Wieser, Arthur Pichler, Andreas Hotter, Ulrich Griesser, Christoph Langes, Christian Laschober
  • CRYSTALLINE FORMS OF TIGECYCLINE HYDROCHLORIDE
    Publication number: 20110105772
    Abstract: The present invention relates to crystalline forms A and B of Tigecycline hydrochloride and to methods for the preparation of the same. Furthermore the present invention relates to the use of crystalline forms A and B of Tigecycline hydrochloride as intermediates for the formulation of an anti-infective medicament. Moreover the present invention relates to pharmaceutical compositions comprising crystalline form A of Tigecycline hydrochloride in an effective amount and to the use of crystalline form A of Tigecycline hydrochloride as anti-infective medicament.
    Type: Application
    Filed: November 12, 2008
    Publication date: May 5, 2011
    Applicant: SANDOZ AG
    Inventors: Josef Wieser, Andreas Hotter, Arthur Pichler
  • A CRYSTALLINE FORM OF POSACONAZOLE
    Publication number: 20110065722
    Abstract: The present invention relates to crystalline form IV of posaconazole and pharmaceutical compositions comprising the same. The pharmaceutical composition can be used to treat or prevent fungal infections.
    Type: Application
    Filed: June 25, 2009
    Publication date: March 17, 2011
    Applicant: Sandoz AG
    Inventors: Josef Wieser, Arthur Pichler, Andreas Hotter, Ulrich Griesser, Christoph Langes
  • ORGANIC COMPOUNDS
    Publication number: 20110015191
    Abstract: Novel polymorph form III of Aprepitant and a method for preparation of novel form III is disclosed. New processes for the preparation of Aprepitant form II are disclosed. The processes involve transformation of form III to form II by heating in decalin and the precipitation of form II from a solvent or solvent mixture by cooling and/or addition of addition of seed crystals or an anti solvent. Solid dispersions containing Aprepitant form II in a suitable carrier are disclosed. A process for the preparation of the solid dispersion by evaporation of a solution of Aprepitant and the carrier in a suitable solvent is disclosed. Stable Aprepitant form II is disclosed. Further pharmaceutical compositions containing Aprepitant form II, III or solid dispersions containing Aprepitant form II in a suitable carrier are disclosed. A methanol solvate of Aprepitant is disclosed.
    Type: Application
    Filed: February 22, 2008
    Publication date: January 20, 2011
    Applicant: SANDOZ AG
    Inventors: Johannes Ludescher, Josef Wieser, Arthur Pichler, Ulrich Griesser, Doris Braun
  • NOVEL SOLVATE
    Publication number: 20100256402
    Abstract: The present invention relates to the novel crystalline form X of Tigecycline and to processes of preparing the same. Furthermore the present invention relates to the use of crystalline form X of Tigecycline as an intermediate for the preparation of an anti-infective medicament.
    Type: Application
    Filed: November 12, 2008
    Publication date: October 7, 2010
    Applicant: Sandoz AG
    Inventors: Andreas Hotter, Josef Wieser, Arthur Pichler
  • METHOD FOR SALT PREPARATION
    Publication number: 20100204470
    Abstract: The present invention provides a new method for preparation and crystallization of hydrochlorides, hydrobromides or hydroiodides of pharmaceutical compounds or their intermediates in which the base or its acid addition salt is reacted in a solvent with a Trialkylsilylhalogenide.
    Type: Application
    Filed: June 25, 2007
    Publication date: August 12, 2010
    Inventors: Josef Wieser, Hannes Lengauer, Elfriede Klingler, Arthur Pichler, Hubert Sturm
  • CRYSTALLINE SOLID FORMS
    Publication number: 20100160264
    Abstract: The present invention relates to the new crystalline solid form VI and VIII of tigecycline and processes for the production of form VI and VIII. It further relates to a new method for preparing Form I and Form III in high polymorphic purity.
    Type: Application
    Filed: June 20, 2008
    Publication date: June 24, 2010
    Inventors: Josef Wieser, Arthur Pichler, Andreas Hotter