Patents by Inventor Arthur R. Mlodozeniec
Arthur R. Mlodozeniec has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 4478822Abstract: This invention relates to a unique drug delivery system for delivering drugs to a body cavity. The drug delivery system comprises a medicament and a polymer such that the drug delivery system is a liquid at room temperature but forms a semi-solid or gel at the body temperature in the body cavity.Type: GrantFiled: May 16, 1983Date of Patent: October 23, 1984Assignee: Merck & Co., Inc.Inventors: John L. Haslam, Takeru Higuchi, Arthur R. Mlodozeniec
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Patent number: 4474752Abstract: Present invention provides a unique drug delivery device for delivering drug by injection into a body. The drug delivery system comprises the drug and polymer which is a liquid at room temperature and a semi-solid or gel at the body temperature.Type: GrantFiled: May 16, 1983Date of Patent: October 2, 1984Assignee: Merck & Co., Inc.Inventors: John L. Haslam, Takeru Higuchi, Arthur R. Mlodozeniec
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Patent number: 4474753Abstract: This invention relates to a unique drug delivery system for application to the skin which drug delivery system is a liquid at room temperature, but when administered topically to the skin becomes a semi-solid or gel when warmed by the body.Type: GrantFiled: May 16, 1983Date of Patent: October 2, 1984Assignee: Merck & Co., Inc.Inventors: John L. Haslam, Takeru Higuchi, Arthur R. Mlodozeniec
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Patent number: 4474751Abstract: This invention describes the application of selected polymers as novel drug delivery systems which use the body temperature and pH to induce a liquid to gel transition of the polymer which contains a drug or therapeutic agent therein. The goal of such a delivery system is to achieve a greater degree of bioavailability or sustained concentration of a drug.Type: GrantFiled: May 16, 1983Date of Patent: October 2, 1984Assignee: Merck & Co., Inc.Inventors: John L. Haslam, Takeru Higuchi, Arthur R. Mlodozeniec
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Patent number: 4349531Abstract: Pharmaceutical dosage forms comprising an edible web having deposited thereon or at least partially thereon a particulate medicament, the webs being thereafter fabricated and finished to pharmaceutically elegant solid dosage forms having no medicament exposed on an exterior surface. The dosage forms have a consistency of release of medicament which can be controlled to exacting specifications. The disclosed solid dosage forms are prepared by high speed automated equipment and the process by which they are made is characterized by non-destructive quality control analysis and performance evaluation both conducted on-line and integrated into the manufacturing operation. Included in the scope of the disclosed invention are certain apparatus and methods of manufacture.Type: GrantFiled: October 4, 1979Date of Patent: September 14, 1982Assignee: Hoffmann-La Roche Inc.Inventors: Arthur R. Mlodozeniec, Arthur H. Goldberg
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Patent number: 4332789Abstract: Pharmaceutical dosage forms comprising an edible web having deposited theron or at least partially thereon a particulate medicament, the webs being thereafter fabricated and finished to pharmaceutically elegant solid dosage forms having no medicament exposed on an exterior surface. The dosage forms have a consistency of release of medicament which can be controlled to exacting specifications. The disclosed solid dosage forms are prepared by high speed automated equipment and the process by which they are made is characterized by non-destructive quality control analysis and performance evaluation both conducted on-line and integrated into the manufacturing operation. Included in the scope of the disclosed invention are certain apparatus and methods of manufacture.Type: GrantFiled: August 24, 1977Date of Patent: June 1, 1982Assignee: Hoffmann-La Roche Inc.Inventor: Arthur R. Mlodozeniec
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Patent number: 4307555Abstract: Pharmaceutical dosage forms comprising an edible web having deposited thereon or at least partially thereon a particulate medicament, the webs being thereafter fabricated and finished to pharmaceutically elegant solid dosage forms having no medicament exposed on an exterior surface. The dosage forms have a consistency of release of medicament which can be controlled to exacting specifications. The disclosed solid dosage forms are prepared by high speed automated equipment and the process by which they are made is characterized by non-destructive quality control analysis and performance evaluation both conducted on-line and integrated into the manufacturing operation. Included in the scope of the disclosed invention are certain apparatus and methods of manufacture.Type: GrantFiled: October 4, 1979Date of Patent: December 29, 1981Assignee: Hoffmann-La Roche Inc.Inventors: Arthur R. Mlodozeniec, Arthur H. Goldberg
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Patent number: 4197289Abstract: Pharmaceutical dosage forms comprising an edible web having deposited thereon or at least partially thereon a particulate medicament, the webs being thereafter fabricated and finished to pharmaceutically elegant solid dosage forms having no medicament exposed on an exterior surface. The doseage forms have a consistency of release of medicament which can be controlled to exacting specifications. The disclosed solid dosage forms are prepared by high speed automated equipment and the process by which they are made is characterized by non-destructive quality control analysis and performance evaluation both conducted on-line and integrated into the manufacturing operation. Included in the scope of the disclosed invention are certain apparatus and methods of manufacture.Type: GrantFiled: August 15, 1978Date of Patent: April 8, 1980Assignee: Hoffmann-La Roche Inc.Inventors: August Sturzenegger, Arthur R. Mlodozeniec, Edward S. Lipinsky
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Patent number: 4128444Abstract: Pharmaceutical dosage forms comprising an edible web having deposited thereon or at least partially thereon a particulate medicament, the webs being thereafter fabricated and finished to pharmaceutically elegant solid dosage forms having no medicament exposed on an exterior surface. The dosage forms have a consistency of release of medicament which can be controlled to exacting specifications. The disclosed solid dosage forms are prepared by high speed automated equipment and the process by which they are made is characterized by non-destructive quality control analysis and performance evaluation both conducted on-line and integrated into the manufacturing operation. Included in the scope of the disclosed invention are certain apparatus and methods of manufacture.Type: GrantFiled: August 10, 1977Date of Patent: December 5, 1978Assignee: Hoffmann-La Roche Inc.Inventor: Arthur R. Mlodozeniec
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Patent number: 4128445Abstract: Pharmaceutical dosage forms comprising an edible web having deposited thereon or at least partially thereon a particulate medicament, the webs being thereafter fabricated and finished to pharmaceutically elegant solid dosage forms having no medicament exposed on an exterior surface. The dosage forms have a consistency of release of medicament which can be controlled to exacting specifications. The disclosed solid dosage forms are prepared by high speed automated equipment and the process by which they are made is characterized by non-destructive quality control analysis and performance evaluation both conducted on-line and integrated into the manufacturing operation. Included in the scope of the disclosed invention are certain apparatus and methods of manufacture.Type: GrantFiled: August 18, 1977Date of Patent: December 5, 1978Assignee: Hoffmann-La Roche Inc.Inventors: August Sturzenegger, Arthur R. Mlodozeniec, Edward S. Lipinsky