Patents by Inventor Arthur Rosenthal
Arthur Rosenthal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7708773Abstract: A modular stent graft system and associated surgical methods are provided that incorporates an external stent-based locking mechanism to prevent disarticulation of the legs from the bifurcated graft as well as other features that overcome many of the difficulties of the prior art associated with delivering and securing the bifurcated grafts to the intended deployment site within the human aorta.Type: GrantFiled: January 20, 2006Date of Patent: May 4, 2010Assignee: Gen4 LLCInventors: Leonard Pinchuk, Arthur Rosenthal
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Patent number: 7537588Abstract: A device and method for delivering and injecting fluid into heart tissue utilizing a laterally directed needle to increase injectate (fluid) retention in the heart tissue. The device may comprise a catheter having a shaft wherein the distal end of the shaft includes a primary penetrating member and a secondary penetrating member. The secondary penetrating member includes an injection lumen in fluid communication with a pressurized fluid source. The primary penetrating member penetrates the heart tissue at the injection site in a first direction, and the secondary penetrating member penetrates the heart tissue in a second direction different from the first direction such that fluid leakage from the injection site is reduced and the volume of treated tissue is increased.Type: GrantFiled: July 27, 2005Date of Patent: May 26, 2009Assignee: Boston Scientific Scimed, Inc.Inventors: Maria Palasis, Arthur Rosenthal
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Patent number: 7445629Abstract: This invention relates generally to medical devices, such as stents, for delivering a biologically active material to a desired location within the body of a patient. In particular, the invention relates generally to a medical device for delivering a biologically active material to a surface of a body lumen. More particularly, the invention is directed to a medical device comprising two opposing end sections, each having a surface, and a middle portion. The middle portion comprises a plurality of struts and the two opposing end sections comprises non-structural elements.Type: GrantFiled: November 11, 2004Date of Patent: November 4, 2008Assignee: Boston Scientific Scimed, Inc.Inventors: Arthur Rosenthal, James J. Barry, Matthew Miller
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Patent number: 7402155Abstract: A catheter for delivering therapeutic to an injection site within the body is provided. This catheter can include a shaft having a proximal end, a distal end, and an infusion lumen extending therein; a penetrating member coupled to the shaft and extendable from the distal end of the shaft, and a stabilizer positioned towards the distal end of the shaft. The catheter could also include a delivery system, able to be calibrated to deliver therapeutic through an injection port at a rate less than the therapeutic absorption rate of the injection site.Type: GrantFiled: February 22, 2002Date of Patent: July 22, 2008Assignee: Boston Scientific Scimed, Inc.Inventors: Maria Palasis, Arthur Rosenthal
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Publication number: 20060217801Abstract: In one embodiment of the present invention a coating topology, or engineered surface architecture that may be referred to as a microdroplet deposited engineered surface architecture is provided. A plurality of drops are placed on the stent with the purpose, of building up individual units of coating material on the outer stent surface. This architecture results in a coating that uses less material, i.e., polymer, solvent, medicine, while at the same time providing for better, and determinable, drug kinetics, approaching 100% delivery and better mechanical operation of the coating binding to the stent.Type: ApplicationFiled: March 27, 2006Publication date: September 28, 2006Applicant: Labcoat, Ltd.Inventor: Arthur Rosenthal
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Publication number: 20060178733Abstract: A modular stent graft system and associated surgical methods are provided that incorporates an external stent-based locking mechanism to prevent disarticulation of the legs from the bifurcated graft as well as other features that overcome many of the difficulties of the prior art associated with delivering and securing the bifurcated grafts to the intended deployment site within the human aorta.Type: ApplicationFiled: January 20, 2006Publication date: August 10, 2006Inventors: Leonard Pinchuk, Arthur Rosenthal
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Patent number: 7066904Abstract: The invention features a method for triggering release of a drug from a hydrogel polymer to tissue at a desired location of the body using a catheter. A portion of the catheter is coated on its outer surface with a polymer having the capacity to incorporate a predetermined substantial amount of drug which is immobilized in the polymer until released by a triggering agent or condition that is different from physiological conditions. Upon contact with a triggering agent or condition, the polymer reacts, e.g., swells or contracts, such that the drug is delivered to the desired body tissue. A balloon catheter is shown in which the hydrogel is carried on the exterior surface of the balloon.Type: GrantFiled: October 25, 2002Date of Patent: June 27, 2006Assignee: Boston Scientific SciMed, Inc.Inventors: Arthur Rosenthal, James J. Barry, Ronald Sahatjian
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Publication number: 20060085058Abstract: A medical device system that is insertable in a body lumen for treating and/or preventing injury to a body lumen wall is disclosed. The system comprises a stent comprising a sidewall having a first edge and a second edge, and a balloon capable of being disposed within the sidewall. The balloon has a first end portion that is capable of contacting the first edge of the sidewall and a second end portion that is capable of contacting the second edge of the sidewall when the balloon is expanded. At least the first end portion of the balloon comprises a first biologically active material. When the balloon is expanded, the first end portion of the balloon extends axially beyond the first edge of the sidewall in order to deliver the first biologically active material to a portion of the body lumen wall that is adjacent to the first edge of the sidewall. Methods for deploying the system are also disclosed.Type: ApplicationFiled: October 20, 2004Publication date: April 20, 2006Inventors: Arthur Rosenthal, James Barry
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Patent number: 6969371Abstract: A device and method for delivering and injecting fluid into heart tissue utilizing a laterally directed needle to increase injectate (fluid) retention in the heart tissue. The device may comprise a catheter having a shaft wherein the distal end of the shaft includes a primary penetrating member and a secondary penetrating member. The secondary penetrating member includes an injection lumen in fluid communication with a pressurized fluid source. The primary penetrating member penetrates the heart tissue at the injection site in a first direction, and the secondary penetrating member penetrates the heart tissue in a second direction different from the first direction such that fluid leakage from the injection site is reduced and the volume of treated tissue is increased.Type: GrantFiled: October 22, 2001Date of Patent: November 29, 2005Assignee: Boston Scientific SciMed, Inc.Inventors: Maria Palasis, Arthur Rosenthal
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Publication number: 20050261662Abstract: A device and method for delivering and injecting fluid into heart tissue utilizing a laterally directed needle to increase injectate (fluid) retention in the heart tissue. The device may comprise a catheter having a shaft wherein the distal end of the shaft includes a primary penetrating member and a secondary penetrating member. The secondary penetrating member includes an injection lumen in fluid communication with a pressurized fluid source. The primary penetrating member penetrates the heart tissue at the injection site in a first direction, and the secondary penetrating member penetrates the heart tissue in a second direction different from the first direction such that fluid leakage from the injection site is reduced and the volume of treated tissue is increased.Type: ApplicationFiled: July 27, 2005Publication date: November 24, 2005Inventors: Maria Palasis, Arthur Rosenthal
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Publication number: 20050113903Abstract: This invention relates generally to medical devices, such as stents, for delivering a biologically active material to a desired location within the body of a patient. In particular, the invention relates generally to a medical device for delivering a biologically active material to a surface of a body lumen. More particularly, the invention is directed to a medical device comprising two opposing end sections, each having a surface, and a middle portion. The middle portion comprises a plurality of struts and the two opposing end sections comprises non-structural elements.Type: ApplicationFiled: November 11, 2004Publication date: May 26, 2005Inventors: Arthur Rosenthal, James Barry, Matthew Miller
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Publication number: 20040009155Abstract: The present invention provides a method of sustaining direct delivery of cells into a target area. The method generally includes delivering cells to a target area. Specifically, the cells are introduced through an introduction site of a target area and delivered to the target area. The method further includes depositing at the introduction site, a plug member that contains a therapeutic agent that is released from the plug member to the target site. at the introduction site. The therapeutic agent generally acts to increase intracellular coupling between the grafted cells and the target area. The plug member also acts to seal the introduction site to inhibit cells from leaking from the introduction site into surrounding areas of the body.Type: ApplicationFiled: July 12, 2002Publication date: January 15, 2004Inventors: Maria Palasis, James J. Barry, Arthur Rosenthal
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Patent number: 6613026Abstract: A device and method for delivering and injecting fluid into heart tissue utilizing laterally directed injection ports to increase injectate (fluid) retention in the heart tissue. The catheter includes a shaft having an infusion lumen extending therethrough, wherein the distal end of the shaft includes a penetrating member having one or more injection ports. The penetrating member penetrates the heart tissue in a first direction, and the injection port or ports direct fluid in a second direction different from the first direction. By injecting the fluid or fluid in a direction different than the penetration direction, fluid leakage from the injection site is reduced and a greater volume of tissue is treated for a single primary injection.Type: GrantFiled: December 8, 1999Date of Patent: September 2, 2003Assignee: SciMed Life Systems, Inc.Inventors: Maria Palasis, Arthur Rosenthal
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Publication number: 20030114791Abstract: The invention features a method for triggering release of a drug from a hydrogel polymer to tissue at a desired location of the body using a catheter. A portion of the catheter is coated on its outer surface with a polymer having the capacity to incorporate a predetermined substantial amount of drug which is immobilized in the polymer until released by a triggering agent or condition that is different from physiological conditions. Upon contact with a triggering agent or condition, the polymer reacts, e.g., swells or contracts, such that the drug is delivered to the desired body tissue. A balloon catheter is shown in which the hydrogel is carried on the exterior surface of the balloon.Type: ApplicationFiled: October 25, 2002Publication date: June 19, 2003Inventors: Arthur Rosenthal, James J. Barry, Ronald Sahatjian
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Patent number: 6524274Abstract: The invention features a method for triggering release of a drug from a hydrogel polymer to tissue at a desired location of the body using a catheter. A portion of the catheter is coated on its outer surface with a polymer having the capacity to incorporate a predetermined substantial amount of drug which is immobilized in the polymer until released by a triggering agent or condition that is different from physiological conditions. Upon contact with a triggering agent or condition, the polymer reacts, e.g., swells or contracts, such that the drug is delivered to the desired body tissue. A balloon catheter is shown in which the hydrogel is carried on the exterior surface of the balloon.Type: GrantFiled: June 7, 1995Date of Patent: February 25, 2003Assignee: Scimed Life Systems, Inc.Inventors: Arthur Rosenthal, James J. Barry, Ronald Sahatjian
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Publication number: 20020095124Abstract: A device and method for delivering and injecting fluid into heart tissue utilizing laterally directed injection ports to increase injectate (fluid) retention in the heart tissue. The catheter includes a shaft having an infusion lumen extending therethrough, wherein the distal end of the shaft includes a penetrating member having one or more injection ports. The penetrating member penetrates the heart tissue in a first direction, and the injection port or ports direct fluid in a second direction different from the first direction. By injecting the fluid or fluid in a direction different than the penetration direction, fluid leakage from the injection site is reduced and a greater volume of tissue is treated for a single primary injection.Type: ApplicationFiled: February 22, 2002Publication date: July 18, 2002Inventors: Maria Palasis, Arthur Rosenthal
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Publication number: 20020026150Abstract: A device and method for delivering and injecting fluid into heart tissue utilizing a laterally directed needle to increase injectate (fluid) retention in the heart tissue. The device may comprise a catheter having a shaft wherein the distal end of the shaft includes a primary penetrating member and a secondary penetrating member. The secondary penetrating member includes an injection lumen in fluid communication with a pressurized fluid source. The primary penetrating member penetrates the heart tissue at the injection site in a first direction, and the secondary penetrating member penetrates the heart tissue in a second direction different from the first direction such that fluid leakage from the injection site is reduced and the volume of treated tissue is increased.Type: ApplicationFiled: October 22, 2001Publication date: February 28, 2002Inventors: Maria Palasis, Arthur Rosenthal
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Patent number: 6319230Abstract: A device and method for delivering and injecting fluid into heart tissue utilizing a laterally directed needle to increase injectate (fluid) retention in the heart tissue. The device may comprise a catheter having a shaft wherein the distal end of the shaft includes a primary penetrating member and a secondary penetrating member. The secondary penetrating member includes an injection lumen in fluid communication with a pressurized fluid source. The primary penetrating member penetrates the heart tissue at the injection site in a first direction, and the secondary penetrating member penetrates the heart tissue in a second direction different from the first direction such that fluid leakage from the injection site is reduced and the volume of treated tissue is increased.Type: GrantFiled: December 8, 1999Date of Patent: November 20, 2001Assignee: Scimed Life Systems, Inc.Inventors: Maria Palasis, Arthur Rosenthal
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Patent number: D387293Type: GrantFiled: April 2, 1996Date of Patent: December 9, 1997Assignee: Jar'sInventor: Joel-Arthur Rosenthal
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Patent number: D390132Type: GrantFiled: December 24, 1996Date of Patent: February 3, 1998Assignee: Jar'sInventor: Joel-Arthur Rosenthal