Patents by Inventor Arthur van den Wijngaard

Arthur van den Wijngaard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Isolated human BMP-4 promoter region
    Patent number: 6159696
    Abstract: The isolated human bone morphogenic protein-4 (BMP-4) promoter region, a vector comprising the isolated promoter region, and host cells comprising the isolated promoter region is described. A method for the identification of potential therapeutic agents for use in the prevention and/or treatment of osteoporosis, comprising the steps of: a) introducing into a cell a first expression vector comprising an isolated BMP-4 promoter region operably linked to a reporter gene, and a second expression vector comprising DNA encoding an estrogen receptor; b) contacting the cell with a candidate agent; and c) monitoring the expression of the protein encoded by the reporter gene, wherein induced expression of the protein indicates that the candidate compound is a potential therapeutic agent, is also described.
    Type: Grant
    Filed: June 21, 1999
    Date of Patent: December 12, 2000
    Assignee: Akzo Nobel N.V.
    Inventors: Rein Dijkema, Arthur van den Wijngaard