Patents by Inventor Artur Cideciyan

Artur Cideciyan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • AAV VECTORS FOR TREATMENT OF DOMINANT RETINITIS PIGMENTOSA
    Publication number: 20210324387
    Abstract: Aspects of the disclosure relate to methods and compositions for treating retinitis pigmentosa. In some aspects, the disclosure provides compositions and methods for delivering an interfering nucleic acid (for example an interfering RNA) to a subject in order to reduce expression of one or both alleles of an endogenous rho gene (for example a mutant rho allele associated with retinitis pigmentosa) in the subject. In some embodiments, a replacement rho gene that is resistant to the interfering nucleic acid also is delivered to the subject.
    Type: Application
    Filed: May 21, 2021
    Publication date: October 21, 2021
    Applicants: Univeristy of Florida Research Foundation, Incorporated, The Trustees of the University of Pennsylvania
    Inventors: Alfred S. Lewin, William W. Hauswirth, Michael T. Massengill, William Beltran, Gustavo D. Aguirre, Artur Cideciyan, Samuel Jacobson
  • AAV vectors for treatment of dominant retinitis pigmentosa
    Patent number: 11118185
    Abstract: Aspects of the disclosure relate to methods and compositions for treating retinitis pigmentosa. In some aspects, the disclosure provides compositions and methods for delivering an interfering nucleic acid (for example an interfering RNA) to a subject in order to reduce expression of one or both alleles of an endogenous rho gene (for example a mutant rho allele associated with retinitis pigmentosa) in the subject. In some embodiments, a replacement rho gene that is resistant to the interfering nucleic acid also is delivered to the subject.
    Type: Grant
    Filed: March 1, 2017
    Date of Patent: September 14, 2021
    Assignees: University of Florida Research Foundation, Incorporated, The Trustees of the University of Pennsylvania
    Inventors: Alfred S. Lewin, William W. Hauswirth, Michael T. Massengill, William Beltran, Gustavo D. Aguirre, Artur Cideciyan, Samuel Jacobson
  • COMPOSITIONS AND METHODS FOR TREATMENT OF DOMINANT RETINITIS PIGMENTOSA
    Publication number: 20210207147
    Abstract: Aspects of the disclosure relate to methods and compositions useful for treating retinitis pigmentosa. In some aspects, the disclosure provides compositions and methods for delivering an interfering RNA to a subject in order to reduce expression of one or both alleles of an endogenous RHO gene (for example a mutant rho allele associated with retinitis pigmentosa) in a subject. In some embodiments, a replacement RHO coding sequence that is resistant to the interfering RNA also is delivered to the subject.
    Type: Application
    Filed: June 3, 2019
    Publication date: July 8, 2021
    Applicants: University of Florida Research Foundation, Incorporated, The Trustees of the University of Pennsylvania
    Inventors: Alfred S. Lewin, William W. Hauswirth, Michael T. Massengill, William Beltran, Gustavo D. Aguirre, Artur Cideciyan, Samuel Jacobson
  • AAV VECTORS FOR TREATMENT OF DOMINANT RETINITIS PIGMENTOSA
    Publication number: 20190093111
    Abstract: Aspects of the disclosure relate to methods and compositions for treating retinitis pigmentosa. In some aspects, the disclosure provides compositions and methods for delivering an interfering nucleic acid (for example an interfering RNA) to a subject in order to reduce expression of one or both alleles of an endogenous rho gene (for example a mutant rho allele associated with retinitis pigmentosa) in the subject. In some embodiments, a replacement rho gene that is resistant to the interfering nucleic acid also is delivered to the subject.
    Type: Application
    Filed: March 1, 2017
    Publication date: March 28, 2019
    Applicants: University of Florida Research Foundation, Incorporated, The Trustees of the University of Pennsylvania
    Inventors: Alfred S. Lewin, William W. Hauswirth, MIchael T. Massengill, William Beltran, Gustavo D. Aguirre, Artur Cideciyan, Samuel Jacovson