Abstract: This invention describes ways of obtaining nano-particulated adjuvants formed by different synthetic variants of GM3 ganglioside. Depending on the fine structure of the fatty acid in the ceramide of the synthetic GM3, said adjuvants are able to stimulate specifically and in a specialized way the humoral or cellular immune response against accompanying antigens. Particularly, this invention provides immunogenic vaccine compositions that comprise peptides, polypeptides or proteins and the aforementioned nanoparticles, which are formed through the dispersion of hydrophobic proteins of the outer membrane complex (OMC) of Neisseria meningitidis in solutions containing fully synthetic variants of the GM3 ganglioside.

Abstract: Described are methods and systems are for generating dynamic conversational queries. For example, as opposed to being a simply reactive system, the methods and systems herein provide means for actively determining a user's intent and generating a dynamic query based on the determined user intent. Moreover, these methods and systems generate these queries in a conversational environment.

Abstract: Described are methods and systems are for generating dynamic conversational queries. For example, as opposed to being a simply reactive system, the methods and systems herein provide means for actively determining a user's intent and generating a dynamic query based on the determined user intent. Moreover, these methods and systems generate these queries in a conversational environment.

Abstract: This disclosure relates to nanoporous pure silica zeolite (PSZ) adsorbents and uses thereof.

Abstract: Methods and systems are described for generating dynamic conversational responses using two-tier machine learning models. The dynamic conversational responses may be generated in real time and reflect the likely goals and/or intents of a user. The two-tier machine learning model may include a first tier that determines an intent cluster based on a feature input, and a second tier that determines a specific intent from the cluster.

Abstract: Methods and systems are presented for generating real-time dynamic conversational responses during conversational interactions using machine learning models based on historic intents for a plurality of users and user-specific interactions. The machine learning models comprise a neural network trained to select a first intent from a plurality of intents based on historic data accumulated prior to the conversational interaction and a neural network trained to select a first interaction-specific intent from a plurality of interaction-specific intents based on interaction-specific data for a user.

Abstract: Methods and systems are described for generating dynamic conversational responses using two-tier machine learning models. The dynamic conversational responses may be generated in real time and reflect the likely goals and/or intents of a user. The two-tier machine learning model may include a first tier that determines an intent cluster based on a feature input, and a second tier that determines a specific intent from the cluster.

Abstract: Methods and systems disclosed herein collect user data in real-time and organize them (e.g., using a collaborative filtering matrix) into groups (e.g., cluster assignments). The system then determines statistical distributions of observed real-time intents (e.g., based on actual selections made by users) for each group. The system then merges this distribution with existing model predictions (e.g., a model trained on historical training data) to balance between historical and dynamically updated information.

Abstract: Methods and systems are described for generating dynamic conversational responses using two-tier machine learning models. The dynamic conversational responses may be generated in real time and reflect the likely goals and/or intents of a user. The two-tier machine learning model may include a first tier that determines an intent cluster based on a feature input, and a second tier that determines a specific intent from the cluster.

Abstract: Described are methods and systems are for generating dynamic conversational queries. For example, as opposed to being a simply reactive system, the methods and systems herein provide means for actively determining a user's intent and generating a dynamic query based on the determined user intent. Moreover, these methods and systems generate these queries in a conversational environment.

Abstract: Methods and systems for generating training data for sequential conversational responses to alleviate the collection burden are disclosed herein. More specifically, the methods and systems describe generating determining dynamic conversational responses to generate training data for sequential conversation responses. For example, the system creates a special form of a random treatment control experiment to reduce the data collection while at the same time generating effectively adequate learning data for intents for the sequenced machine learning.

Abstract: Methods and systems disclosed herein collect user data in real-time and organize them (e.g., using a collaborative filtering matrix) into groups (e.g., cluster assignments). The system then determines statistical distributions of observed real-time intents (e.g., based on actual selections made by users) for each group. The system then merges this distribution with existing model predictions (e.g., a model trained on historical training data) to balance between historical and dynamically updated information.

Abstract: Methods and systems are described for generating dynamic conversational responses using two-tier machine learning models. The dynamic conversational responses may be generated in real time and reflect the likely goals and/or intents of a user. The two-tier machine learning model may include a first tier that determines an intent cluster based on a feature input, and a second tier that determines a specific intent from the cluster.

Abstract: Methods and systems are described for generating dynamic conversational responses using two-tier machine learning models. The dynamic conversational responses may be generated in real time and reflect the likely goals and/or intents of a user. The two-tier machine learning model may include a first tier that determines an intent cluster based on a feature input, and a second tier that determines a specific intent from the cluster.

Abstract: Methods and systems are described for generating dynamic conversational responses using two-tier machine learning models. The dynamic conversational responses may be generated in real time and reflect the likely goals and/or intents of a user. The two-tier machine learning model may include a first tier that determines an intent cluster based on a feature input, and a second tier that determines a specific intent from the cluster.

Abstract: Methods and systems are described for generating dynamic interface options using machine learning models. The dynamic interface options may be generated in real time and reflect the likely goals and/or intents of a user. The machine learning model may provide these features by interpreting multi-modal feature inputs. For example, the machine learning model may include a first machine learning model, wherein the first machine learning model comprises a convolutional neural network, and a second machine learning model, wherein the second machine learning model performs a Weight of Evidence (WOE) analysis.

Abstract: A circuit includes a primary light emitting diode (LED) string, a secondary LED string, a reference line, and primary and secondary transistors. The primary string includes a voltage drop, and a node disposed between two adjacent LEDs of the primary string. The secondary string is configured in parallel with the primary string. The secondary string has a voltage drop that is less than the primary voltage drop. The reference line is coupled to the node. The primary transistor includes a drain, a gate, and a source. The drain is coupled to a primary string output terminal. The gate is coupled to the reference line, and the source is coupled to a ground. The secondary transistor includes a drain, a gate, and a source. The drain is coupled to a secondary string output terminal. The gate is coupled to the reference line, and the source is coupled to the ground.

Abstract: Methods and systems are described for generating dynamic conversational responses using two-tier machine learning models. The dynamic conversational responses may be generated in real time and reflect the likely goals and/or intents of a user. The two-tier machine learning model may include a first tier that determines an intent cluster based on a feature input, and a second tier that determines a specific intent from the cluster.

Abstract: The invention provides the incorporation of Co2+, Ni2+ or Cu2+ onto the surface of mesoporous SBA-15 via an amino-organic grafting method and the screening of materials as sorbents for the removal of Naproxen from water.

Abstract: An extrusion machine and method of use for making a multi-structure gummy candy. Specifically, the multi-structure candy provides a gummy center encapsulated by hard candy.