Patents by Inventor Arulmozhi Natrajan Madhiyazhagan

Arulmozhi Natrajan Madhiyazhagan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mutated cephalosporin hydroxylase and its application in deacetylcephalosporanic acid synthesis
    Patent number: 9404139
    Abstract: A mutant hydroxylase with increased activity and greater substrate specificity towards phenylacetyl-7-ADCA derivatives for the production of phenylacetyl-7-HACA derivatives, which carries one or more amino acid modification at residue positions when compared with certain wild type hydroxylase from certain groups of residues. Also disclosed is a process for the preparation of deacetyl cephalosporanic acid from the corresponding deacetoxy cephalosporanic acid that includes an enzyme of the present invention. Also provided is a method for the production and processing of such enzymes.
    Type: Grant
    Filed: January 9, 2013
    Date of Patent: August 2, 2016
    Assignee: ORCHID CHEMICALS & PHARMACEUTICALS LIMITED
    Inventors: Micheal Durairaaj, Ramanan Thirumoorthy, Kanhu Charan Mishra, Thangadurai Chinnathambi, Cavery Manian Krishnan, Padma Rajasekaran, Sugumar Subramani, Kavitha Daffrose Selvaraj, Nataraj Balakrishnan, Sathish Ravikumar Chakravarthy, Arulmozhi Natrajan Madhiyazhagan
  • MUTATED CEPHALOSPORIN HYDROXYLASE AND ITS APPLICATION IN DEACETYLCEPHALOSPORANIC ACID SYNTHESIS
    Publication number: 20150240282
    Abstract: A mutant hydroxylase with increased activity and greater substrate specificity towards phenylacetyl-7-ADCA derivatives for the production of phenylacetyl-7-HACA derivatives, which carries one or more amino acid modification at residue positions when compared with certain wild type hydroxylase from certain groups of residues. Also disclosed is a process for the preparation of deacetyl cephalosporanic acid from the corresponding deacetoxy cephalosporanic acid that includes an enzyme of the present invention. Also provided is a method for the production and processing of such enzymes.
    Type: Application
    Filed: January 9, 2013
    Publication date: August 27, 2015
    Inventors: Micheal Durairaaj, Ramanan Thirumoorthy, Kanhu Charan Mishra, Thangadurai Chinnathambi, Cavery Manian Krishnan, Padma Rajasekaran, Sugumar Subramani, Kavitha Daffrose Selvaraj, Nataraj Balakrishnan, Sathish Ravikumar Chakravarthy, Arulmozhi Natrajan Madhiyazhagan