Patents by Inventor Arumugam Balasubramanian

Arumugam Balasubramanian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230021514
    Abstract: Disclosed are an etelcalcetide intermediate and a method for synthesizing etelcalcetide. The etelcalcetide intermediate is Fmoc-D-Cys(S—S—(N-Boc)-L-Cys(OtBu))-OH. The method for synthesizing the etelcalcetide includes the following steps: using N-Boc-L-Cqs-OtBu as a starting material to generate a primary product of a formula (A) by means of a substitution reaction, herein R is S-Py or Cl; and performing a coupling reaction on the primary product and Fmoc-D-Cys-OH amino acid to obtain Fmoc-D-Cys(S—S—(N-Boc)-L-Cys(OtBu))-OH. The key intermediate is used for synthesizing the etelcalcetide, which may improve the purity and the yield. It is important that the raw materials for synthesizing the key intermediate are cheap and readily available, and the process is simple.
    Type: Application
    Filed: December 27, 2019
    Publication date: January 26, 2023
    Inventors: Jiuyuan LI, Johnson MATT, Changfeng LI, Lutao JING, Arumugam BALASUBRAMANIAN, Xiaolong LEI, Zili ZHU
  • Publication number: 20100086724
    Abstract: A recording layer including a novel organic dye compound (I) for a high density optical recording medium is provided. The organic dye compound (I) has the following general chemical structural formula: wherein [A]+ includes alkaline metal ion, wherein R1, R2, R3, R4, R5 and R6 each independently represent hydrogen, straight or branched C1-8 alkyl, C1-3 alkoxyl, halogen, nitro, benzyl group or substituted benzyl group wherein a substituent thereof is C1-2 alkyl, C1-2 alkoxyl, halogen or nitro. The organic dye compound (I) exhibits a maximum absorbance at a wavelength range of 400-550 nm.
    Type: Application
    Filed: September 24, 2009
    Publication date: April 8, 2010
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Shin-Shin Wang, Arumugam Balasubramanian, Chien-Liang Huang, Chung-Ta Cheng
  • Publication number: 20100047509
    Abstract: A recording layer including a novel organic dye compound (I) for a high density optical recording medium is provided. The organic dye compound (I) has the following general chemical structural formula: wherein R1, R2, R3, R4 and R5 each independently represent H, alkyl, halide, nitro, benzyl group or substituted benzyl group. The organic dye compound (I) exhibits a maximum absorbance at a wavelength range of 400-550 nm.
    Type: Application
    Filed: July 30, 2008
    Publication date: February 25, 2010
    Applicant: Industrial Technology Research Institute
    Inventors: Shin-Shin Wang, Arumugam Balasubramanian, Chien-Liang Huang, Chung-Ta Cheng