Patents by Inventor Arun K. Bhunia
Arun K. Bhunia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11567002Abstract: A system for the identification of micro-organisms includes an irradiation unit adapted to sequentially provide coherent electromagnetic radiation of one or more wavelengths along a common optical path. A holder is adapted to retain a substrate having a surface adapted for growth of a micro-organism colony. A beamsplitter is adapted to direct the coherent electromagnetic radiation from the common optical path towards the retained substrate. An imager is arranged opposite the beamsplitter from the retained substrate and is adapted to obtain images of backward-scattered light patterns from the micro-organism colony irradiated by the respective wavelengths of the directed coherent electromagnetic radiation. Some examples provide radiation of multiple wavelengths and include an imager arranged optically downstream of the retained substrate to obtain images of forward-scattered light patterns from the micro-organism colony irradiated by the wavelengths of radiation.Type: GrantFiled: September 2, 2020Date of Patent: January 31, 2023Assignee: Purdue Research FoundationInventors: Euiwon Bae, Arun K. Bhunia, Edwin Daniel Hirleman, Huisung Kim, Bartlomiej Rajwa, Joseph Paul Robinson, Valery Patsekin
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Publication number: 20210386819Abstract: In some illustrative embodiments, the present disclosure relates to a method for treating or preventing an inflammatory condition of a patient comprising the step of administering a therapeutically effective amount of Next Generation Bioengineered Probiotics (NGBP), together with one or more pharmaceutically acceptable carriers, diluents, and excipients, to the patient in need of relief from said inflammatory condition. In some other embodiments, the present application relates to an animal feed supplement for improving animal health and meat production compromising Next Generation Bioengineered Probiotics (NGBP). Yet in some other embodiments, the present invention relates to method for improving animal health and/or meat production comprising the step of adding an effective amount of Next Generation Bioengineered Probiotics (NGBP) to the feed of said animal.Type: ApplicationFiled: August 13, 2021Publication date: December 16, 2021Applicant: Purdue Research FoundationInventors: Arun K Bhunia, Rishi Drolia, OK Kyung Koo, Mary Anne Amalaradjou
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Patent number: 11090357Abstract: The present application relates to an animal feed supplement for improving animal health and meat production compromising Next Generation Bioengineered Probiotics (NGBP). In some embodiments, the present application relates to a method for treating or preventing an inflammatory condition of a patient comprising the step of administering a therapeutically effective amount of Generation Bioengineered Probiotics (NGBP), together with one or more pharmaceutically acceptable carriers, diluents, and excipients, to the patient in need of relief from said inflammatory condition. In some other embodiments, the present invention relates to method for improving animal health and/or meat production comprising the step of adding an effective amount of Next Generation Bioengineered Probiotics (NGBP) to the feed of said animal.Type: GrantFiled: July 1, 2019Date of Patent: August 17, 2021Assignee: Purdue Research FoundationInventors: Arun K Bhunia, Rishi Drolia, Ok Kyung Koo, Mary Anne Amalaradjou
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Patent number: 10632208Abstract: This present application relates to a drug delivery method. In particular, the present invention discloses a non-invasive drug delivery method using Listeria adhesion protein (LAP) an analogue, or a fragment thereof. Incorporation of those peptides or a fragment thereof, either by a physical mixture of a pharmaceutical formulation or as a covalent construction at a molecular level or nanoscale is within the scope of this disclosure.Type: GrantFiled: October 4, 2018Date of Patent: April 28, 2020Assignee: Purdue Research FoundationInventors: Arun K. Bhunia, Rishi Drolia, Manalee Samaddar
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Publication number: 20200000876Abstract: The present application relates to an animal feed supplement for improving animal health and meat production compromising Next Generation Bioengineered Probiotics (NGBP). In some embodiments, the present application relates to a method for treating or preventing an inflammatory condition of a patient comprising the step of administering a therapeutically effective amount of Generation Bioengineered Probiotics (NGBP), together with one or more pharmaceutically acceptable carriers, diluents, and excipients, to the patient in need of relief from said inflammatory condition. In some other embodiments, the present invention relates to method for improving animal health and/or meat production comprising the step of adding an effective amount of Next Generation Bioengineered Probiotics (NGBP) to the feed of said animal.Type: ApplicationFiled: July 1, 2019Publication date: January 2, 2020Applicant: Purdue Research FoundationInventors: Arun K Bhunia, Rishi Drolia, OK Kyung Koo, Mary Anne Amalaradjou
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Publication number: 20190105401Abstract: This present application relates to a drug delivery method. In particular, the present invention discloses a non-invasive drug delivery method using Listeria adhesion protein (LAP) an analogue, or a fragment thereof. Incorporation of those peptides or a fragment thereof, either by a physical mixture of a pharmaceutical formulation or as a covalent construction at a molecular level or nanoscale is within the scope of this disclosure.Type: ApplicationFiled: October 4, 2018Publication date: April 11, 2019Applicant: Purdue Research FoundationInventors: Arun K. Bhunia, Rishi Drolia, Manalee Samaddar
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Publication number: 20170219485Abstract: A system for the identification of micro-organisms includes an irradiation unit adapted to sequentially provide coherent electromagnetic radiation of one or more wavelengths along a common optical path. A holder is adapted to retain a substrate having a surface adapted for growth of a micro-organism colony. A beamsplitter is adapted to direct the coherent electromagnetic radiation from the common optical path towards the retained substrate. An imager is arranged opposite the beamsplitter from the retained substrate and is adapted to obtain images of backward-scattered light patterns from the micro-organism colony irradiated by the respective wavelengths of the directed coherent electromagnetic radiation. Some examples provide radiation of multiple wavelengths and include an imager arranged optically downstream of the retained substrate to obtain images of forward-scattered light patterns from the micro-organism colony irradiated by the wavelengths of radiation.Type: ApplicationFiled: October 1, 2015Publication date: August 3, 2017Inventors: Euiwon Bae, Arun K. Bhunia, Edwin Daniel Hirleman, Huisung Kim, Bartlomiej P. Rajwa, Joseph Paul Robinson, Valery Patsekin
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Patent number: 8787633Abstract: A system and method for identifying organisms by analysis of scattergrams of colonies is disclosed. cattergrams are obtained by culturing samples and illuminating the resultant colonies by a laser. The forward scattered light is imaged and subject to a feature extraction process. The feature vector may include Zernike or Chebyshev moments and may also include Harelick texture features. Feature vectors may be used to train a classification process using either supervised or unsupervised machine learning techniques. The classification process may be used to associate a colony phenotype with the genotype of the sample.Type: GrantFiled: January 11, 2008Date of Patent: July 22, 2014Assignee: Purdue Research FoundationInventors: J. Paul Robinson, Bartlomiej Rajwa, Bulent Bayraktar, Arun K. Bhunia, E. Daniel Hirleman, Euiwon Bae
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Publication number: 20140066363Abstract: A nanoparticle includes a carbohydrate carrier and a bacteriocin. A method for prolonging efficacy of a bacteriocin against a food pathogen includes providing the bacteriocin in a delivery system, and inhibiting the food pathogen by the bacteriocin. A duration of efficacy of the bacteriocin against the food pathogen when the bacteriocin is provided in the delivery system exceeds a duration of efficacy of the bacteriocin when the bacteriocin is provided without the delivery system.Type: ApplicationFiled: February 6, 2012Publication date: March 6, 2014Inventors: Arun K. Bhunia, Yuan Yao
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Publication number: 20080310692Abstract: A system and method for identifying organisms by analysis of scattergrams of colonies is disclosed. cattergrams are obtained by culturing samples and illuminating the resultant colonies by a laser. The forward scattered light is imaged and subject to a feature extraction process. The feature vector may include Zernike or Chebyshev moments and may also include Harelick texture features. Feature vectors may be used to train a classification process using either supervised or unsupervised machine learning techniques. The classification process may be used to associate a colony phenotype with the genotype of the sample.Type: ApplicationFiled: January 11, 2008Publication date: December 18, 2008Inventors: J. Paul Robinson, Bartlomiej Rajwa, Bulent Bayraktar, Arun K. Bhunia, E. Daniel Hirleman, Euiwon Bae
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Patent number: 7465560Abstract: A system and a method of detecting and characterizing a bacterial colony are presented in which the results are determined within about 48 hours. The bacterial colony is disposed on a substrate and placed between a laser and detector. Light from the laser impinges upon and is scattered by the bacterial colony. The forward scattered light is detected by an optical detector. The signal from the optical detector is analyzed by an analyzer and displayed or supplied to a storage medium for review. As different strains of bacteria possess unique forward scattering fingerprints, the particular strain may be identified.Type: GrantFiled: November 30, 2005Date of Patent: December 16, 2008Assignee: Purdue Research FoundationInventors: Edwin D. Hirleman, Jr., Songling Guo, Arun K. Bhunia, Euiwon Bae
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Patent number: 7306924Abstract: A method for collecting a microbiological substance utilizes a micro fabricated biochip having a collection chamber. A fluid sample containing a microbiological entity of interest is delivered to the collection chamber in the biochip. Then a non-uniform electric field is generated in the collection chamber, to retain the microbiological entity of interest in the collection chamber. The microbiological entity is retained through dielectrophoresis induced by the energization of the electrodes by a periodically applied, alternating current.Type: GrantFiled: June 26, 2002Date of Patent: December 11, 2007Assignee: Purdue Research FoundationInventors: Rafael Gomez, Rashid Bashir, Arun K. Bhunia, Michael R. Ladisch, J. Paul Robinson
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Publication number: 20030157587Abstract: A method for collecting a microbiological substance utilizes a microfabricated biochip having a collection chamber. A fluid sample containing a microbiological entity of interest is delivered to the collection chamber in the biochip. Then a non-uniform electric field is generated in the collection chamber, to retain the microbiological entity of interest in the collection chamber. The microbiological entity is retained through dielectrophoresis induced by the energization of the electrodes by a periodically applied, alternating current.Type: ApplicationFiled: June 26, 2002Publication date: August 21, 2003Inventors: Rafael Gomez, Rashid Bashir, Arun K. Bhunia, Michael R. Ladisch, J. Paul Robinson
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Publication number: 20030036054Abstract: A microscale biosensor for use in the detection of target biological substances including molecules and cells is a microfluidic system with integrated electronics, inlet-outlet ports and interface schemes, high sensitivity detection of pathogen specificity, and processing of biological materials at semiconductor interfaces. A fabrication process includes an all top-side processing for the formation of fluidic channels, planar fluidic interface ports, integrated metal electrodes for impedance measurements, and a glass cover sealing the non-planar topography of the chip using spin-on-glass as an intermediate bonding layer. Detection sensitivity is enhanced by small fluid volumes, use of a low-conductivity buffer, and electrical magnitude or phase measurements over a range of frequencies.Type: ApplicationFiled: June 14, 2002Publication date: February 20, 2003Applicant: Purdue Research FoundationInventors: Michael R. Ladisch, Rashid Bashir, Arun K. Bhunia, Rafael Gomez
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Publication number: 20010053535Abstract: A microscale biosensor for use in the detection of target biological substances including molecules and cells is a microfluidic system with integrated electronics, inlet-outlet ports and interface schemes, high sensitivity detection of pathogen specificity, and processing of biological materials at semiconductor interfaces. A fabrication process includes an all top-side processing for the formation of fluidic channels, planar fluidic interface ports, integrated metal electrodes for impedance measurements, and a glass cover sealing the non-planar topography of the chip using spin-on-glass as an intermediate bonding layer. Detection sensitivity is enhanced by small fluid volumes, use of a low-conductivity buffer, and electrical magnitude or phase measurements over a range of frequencies.Type: ApplicationFiled: March 26, 2001Publication date: December 20, 2001Applicant: PURDUE RESEARCH FOUNDATIONInventors: Rashid Bashir, Arun K. Bhunia, Rafael Gomez, Michael R. Ladisch, J. Paul Robinson, Ayda Sarikaya