Abstract: A method and apparatus for controlling a plurality of solar panels of a spacecraft is described. The method comprises the steps of providing a first step command to a first solar panel, and providing a second step command to a second solar panel at a time of a transient zero-crossing of a dynamic response of the spacecraft body to the first step command, wherein the second solar panel is disposed on an opposite side of the spacecraft from the first solar panel. The apparatus comprises a processor; a first solar panel driver, communicatively coupled to the processor, for providing a first step command to a first solar panel, and a second solar panel driver, communicatively coupled to the processor, for providing a second step command to a second solar panel at a time of a transient zero-crossing of a dynamic response of the spacecraft body to the first step command.

Abstract: This invention relates to a process for preparation of taxanes comprising subjecting 7,10-diprotected intermediates 7-O-(2-haloacyl)baccatin III 6c or 7,10-O-di-(2-haloacyl)-10-deacetylbaccatin III 6b to a step of coupling with (4S,5R)-3-[(2-alkyl/aryl-2-trialkylsilyl)ethoxy-carbonyl]-4-aryl-2-substituted-1,3-oxazolidine-5-carboxylic acid 1 in the presence of a condensation agent, an activating agent and an aromatic hydrocarbon to obtain 7-O-[2-(haloacyl)]-13-[(4S,5R)-4-aryl-2-substituted-3(2-unsubstituted/substituted-2-trialkylsilyl)-ethoxycarbonyl-1,3-oxazolidinyl-5-carbonyl]baccatin III 7a or 7,10-di-O[2-(haloacyl)]-13-[(4S,5R)-4-aryl-2-substituted-3-(2-unsubstituted/substituted-2-trialkylsilyl)ethoxy-carbonyl-1,3-oxazolidinyl-5-carbonyl]-10-deacetylbaccatin III 7b; treating the coupled products 7-O-[2-(haloacyl)]-13-[(4S,5R)-4-aryl-2-substituted-3-(2-substituted-2-trialkylsilyl)ethoxy-carbonyl-1,3-oxazolidinyl-5-carbonyl]baccatin III 7a or 7,10-di-O-[2[(haloacyl)]-13-[(4S,5R)-4-aryl-2-substituted-3-(2-su

Abstract: The method of present invention and the device used therein is directed for characterizing unknown metallic flakes present in an existing coating on a substrate such that a matching metallic paint composition can be formulated and applied over the substrate to produce a metallic coating having characteristics, such as flop, that match the existing coating.

Abstract: A method of determining the attitude of a spinning spacecraft is provided. The method includes stabilizing the spacecraft, initializing the attitude of the spacecraft using star tracker data, and estimating the attitude of the spacecraft.

Abstract: A process for the preparation of taxanes comprising wherein R is a tert. butoxycarbonyl or benzoyl group; PMP is p-methoxyphenyl group; G1 is acetyl group; G2 is haloacetyl group comprising a) protecting the C-7 hydroxyl group of 10-deacetylbaccatin III with haloacetyl chlorides and then acetylating the C-10 hydroxyl group with acetyl chloride to obtain a protected 10-deacetylbaccatin III (1); b) subjecting the protected 10-deacetylbaccatin III (1) to coupling with an oxazolidine-5-caboxylic acid of formula 2 wherein R is tert. butoxycarbonyl or benzoyl; PMP is p-methoxyphenyl group in the presence of a condensation agent and an activating agent to obtain C-13 esters of formula 3; c) treating the coupled products 3 with weak acidic medium to open the oxazolidine ring to obtain intermediates of formula 4; wherein R is a tert.

Abstract: A method and apparatus for controlling a plurality of solar panels of a spacecraft is described. The method comprises the steps of providing a first step command to a first solar panel, and providing a second step command to a second solar panel at a time of a transient zero-crossing of a dynamic response of the spacecraft body to the first step command, wherein the second solar panel is disposed on an opposite side of the spacecraft from the first solar panel. The apparatus comprises a processor, a first solar panel driver, communicatively coupled to the processor, for providing a first step command to a first solar panel, and a second solar panel driver, communicatively coupled to the processor, for providing a second step command to a second solar panel at a time of a transient zero-crossing of a dynamic response of the spacecraft body to the first step command.

Abstract: A process for the preparation of taxanes including paclitaxel, docetaxel, and structurally similar analogs, as well as intermediates produced by the process.

Abstract: A process for the purification of paclitaxel or docetaxel comprising: (a) mixing crude paclitaxel with a mixture of solvents such as alkane and chlorinated alkane, filtering the solid followed by drying to obtain paclitaxel or docetaxel of increased purity; (b) repeating step (a) one or more times to obtain paclitaxel or docetaxel of increased purity; (c) dissolving the solid obtained from step (b) in alkyl ketone followed by adding alkane thereto, filtering and drying the solid thus formed to obtain paclitaxel or docetaxel of increased purity; (d) repeating step (c) one or more times to increase the purity of paclitaxel or docetaxel; (e) dissolving the paclitaxel or docetaxel obtained from step (d) in alkanol and then adding water, filtering and drying the solid thus formed, to obtain paclitaxel of increased purity; (f) dissolving the solid obtained from step (e) in alkyl ketone, filtering, followed by adding alkane to the filtrate, filtering and drying the solid thus formed to obtain pure paclitaxel or pure

Abstract: A process for converting paclitaxel or docetaxel to the respective trihydrate characterized by very high purity, comprises dissolving either paclitaxel or docetaxel in a mixture of alkane and chlorinated alkane to provide a crude product of 65-75% assay and dissolving the crude product in an alkyl ketone, followed by addition of an alkane to provide a product of increased chromatographic purity; dissolving the product of increased chromatographic purity in an aliphatic nitrile, with addition of water to precipitate taxane trihydrate.

Abstract: The method of present invention and the device used therein is directed for characterizing unknown metallic flakes present in an existing coating on a substrate such that a matching metallic paint composition can be formulated and applied over the substrate to produce a metallic coating having characteristics, such as flop, that match the existing coating.

Abstract: A process for the preparation of paclitaxel trihydrate and doctaxel trihydrate comprising (a) treating taxane selected from paclitaxel and docetaxel with a mixture of alkane and chlorinated alkane to obtain a crude product of 65-75% assay, (b) dissolving the crude product thus obtained in alkyl ketone followed by slow addition of an alkane to increase chromatographic purity, (c) dissolving the taxane of step (b) in an aliphatic nitrile at a temperature of 50-70° C., (d) adding purified water to the product of step (c) to precipitate taxane trihydrate; and (e) filtering and drying the product of step (d) to obtain taxane trihydrate of C.P. >99.5% and 98-102% assay.

Abstract: A process for the preparation of taxanes comprising 1

Abstract: This invention relates to a process for preparation of taxanes comprising

Abstract: A process for the purification of paclitaxel comprising: (a) mixing crude paclitaxel with a mixture of solvents such as alkane and chlorinated alkane, filtering the solid followed by drying to obtain paclitaxel of increased purity; (b) repeating step (a) one or more times to obtain paclitaxel of increased purity; (c) dissolving the solid obtained from step (b) in alkyl ketone followed by adding alkane thereto, filtering and drying the solid thus formed to obtain paclitaxel of increased purity; (d) repeating step (c) one or more times to increase the purity of paclitaxel; (e) dissolving the paclitaxel obtained from step (d) in alkanol and then adding water, filtering and drying the solid thus formed, to obtain paclitaxel of increased purity; and (f) dissolving the solid obtained from step (e) in alkyl ketone, filtering, followed by adding alkane to the filtrate, filtering and drying the solid thus formed to obtain pure paclitaxel.

Abstract: A process for the preparation of taxanes including paclitaxel, docetaxel, and structurally similar analogs, as well as intermediates produced by the process.

Abstract: 3-(alk-2-ynyloxy)carbonyl-5-oxazolidine carboxylic acid and its analogs having a formula 1

Abstract: 3-(alk-2-ynyloxy)carbonyl-5-oxazolidine carboxylic acid and its analogs having a formula and wherein R1 is hydrogen, aryl, heteroaryl, alkyl, alkenyl, alkynyl, R2 and R3 are independently selected from hydrogen, alkyl, alkenyl, alkynyl, aryl, heteroaryl, R4 is hydrogen, alkyl, alkenyl, alkynyl, aryl, substituted aryl, heteroaryl, R5 and R6 independently selected from hydrogen, alkyl, alkenyl,alkynyl, arly, heteroaryl, alkoxy, alkeyloxy, alkynyloxy, aryloxy, heteroaryloxy.

Abstract: In one embodiment of the present invention, a cost savings analysis system includes one or more software components. The software components collectively receive from a user one or more first inputs specifying a cost savings goal and one or more second inputs specifying a technique for generating a baseline price. The software components collectively access historical transaction data within one or more databases needed to generate a baseline price according to the specified technique, generate the baseline price, determine a variation between the generated baseline price and an actual price for each of one or more transactions corresponding to the specified cost savings goal, and compare the determined variations for the one or more transactions with the specified cost savings goal to conduct a baseline cost savings analysis.

Abstract: This invention relates to a method and apparatus for determining the flatness or planarity of a surface and, specifically, to a method and apparatus for determining the flatness or planarity of a surface using a computerized optics technique.

Abstract: The locality of a two dimensional gray level image from which is generated a reference threshold value for converting the image to its corresponding binary image is determined by finding the fractal dimension of a hypothetical three dimensional surface overlying the two dimensional image.