Patents by Inventor Aruna S. Jaiswal

Aruna S. Jaiswal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9914733
    Abstract: The instant invention describes biisoquinoline compounds having therapeutic activity, and methods of treating disorders such as cancer, tumors and cell proliferation related disorders, or affect cell differentiation, dedifferentiation or transdifferentiation.
    Type: Grant
    Filed: March 30, 2015
    Date of Patent: March 13, 2018
    Assignee: University of Florida Research Foundation, Incorporated
    Inventors: Satya Narayan, Sukwon Hong, Aruna S. Jaiswal
  • Publication number: 20170183349
    Abstract: The instant invention describes biisoquinoline compounds having therapeutic activity, and methods of treating dis-orders such as cancer, tumors and cell proliferation related disorders, or affect cell differentiation, dedifferentiation or transdifferentiation.
    Type: Application
    Filed: March 30, 2015
    Publication date: June 29, 2017
    Inventors: Satya NARAYAN, Sukwon HONG, Aruna S. JAISWAL
  • Patent number: 9517244
    Abstract: The invention features compositions and methods that are useful for the treatment of neoplasia (e.g., pancreatic cancer, colon cancer, brain cancer) by increasing DNA damage, reducing nucleotide synthesis, and reducing base excision repair (BER).
    Type: Grant
    Filed: April 20, 2012
    Date of Patent: December 13, 2016
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Satya Narayan, Aruna S. Jaiswal, David A. Ostrov, Sukwon Hong
  • Patent number: 9144596
    Abstract: The invention features compositions and methods that are useful for the treatment of neoplasia by reducing base excision repair (BER). Such compositions are useful, for example, for enhancing the efficacy of known chemotherapeutics, such as DNA alkylating agents. In particular, the invention features agents that mimic the interaction of APC with pol-?. Such agents reduce the activity of long patch- and single nucleotide-base extension repair pathways.
    Type: Grant
    Filed: February 14, 2008
    Date of Patent: September 29, 2015
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Satya Narayan, Aruna S. Jaiswal, David A. Ostrov
  • Patent number: 8815828
    Abstract: The invention features compositions and methods that are useful for the treatment of neoplasia (e.g., breast cancer) by increasing DNA damage and reducing base excision repair (BER).
    Type: Grant
    Filed: June 29, 2009
    Date of Patent: August 26, 2014
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Satya Narayan, Aruna S. Jaiswal, David A. Ostrov
  • Publication number: 20140134275
    Abstract: The invention features compositions and methods that are useful for the treatment of neoplasia (e.g., pancreatic cancer, colon cancer, brain cancer) by increasing DNA damage, reducing nucleotide synthesis, and reducing base excision repair (BER).
    Type: Application
    Filed: April 20, 2012
    Publication date: May 15, 2014
    Applicant: University of Florida Research Foundation
    Inventors: Satya Narayan, Aruna S. Jaiswal, David A. Ostov, Sukwon Hong
  • Publication number: 20110152206
    Abstract: The invention features compositions and methods that are useful for the treatment of neoplasia (e.g., breast cancer) by increasing DNA damage and reducing base excision repair (BER).
    Type: Application
    Filed: June 29, 2009
    Publication date: June 23, 2011
    Applicant: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.
    Inventors: Satya Narayan, Aruna S. Jaiswal, David A. Ostrov
  • Publication number: 20100190702
    Abstract: The invention features compositions and methods that are useful for the treatment of neoplasia by reducing base excision repair (BER). Such compositions are useful, for example, for enhancing the efficacy of known chemotherapeutics, such as DNA alkylating agents. In particular, the invention features agents that mimic the interaction of APC with pol-?. Such agents reduce the activity of long patch- and single nucleotide-base extension repair pathways.
    Type: Application
    Filed: February 14, 2008
    Publication date: July 29, 2010
    Applicant: University of Florida Research Foundation
    Inventors: Satya Narayan, Aruna S. Jaiswal, David A. Ostrov