Abstract: A computer-implemented method for performing Medication Regimen Reviews (MRR) includes synchronizing a local medication regimen database stored on a client computing device with a remote medication regimen database stored on a server computing device. The local medication regimen database includes medication regimens for patients residing at one or more facilities. Medication regimen recommendations are created based on input received via a client interface on the client computing device. Each medication regimen recommendation is created by a recommendation process. These medication regimen recommendations may then be stored in a local medication recommendations database on the client computing device.