Abstract: Methods and systems for the transfer of samples collected on swabs (or similar sample collectors) onto particular types of substrates for subsequent analysis or other processing. The method involves contacting the sample collector containing a sample including the charged substance with the electrophoresis matrix; applying an electric field across the electrophoresis matrix to effect transfer of the charged substance from the sample collector to the electrophoresis matrix. The useful systems may assist in the performance of an operation on a charged substances within an electrophoresis system. Such systems may include a first electrolyte reservoir including a first electrode; a second electrolyte reservoir including a second electrode; a thread extending between the first and second electrolyte reservoirs; a third reservoir through which the thread passes, and a controller for controlling the application of an electric field across the thread so as to effect movement of a charged substance along the thread.