Patents by Inventor Arvin C. Dar

Arvin C. Dar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PERFLUOROALKANE SUBSTITUTED PYRAZOLO[3,4-D]PYRIMIDIN AND PYRROLO[2,3-D]PYRIMIDIN COMPOUNDS AND USES THEREOF
    Publication number: 20240287081
    Abstract: The present disclosure relates to compounds of formula (I) having the following structure; and to compounds of formula (II) having the structure: or stereoisomers, pharmaceutically acceptable salts, oxides, or solvates thereof, where R1, R2, R3, R4, and R5 are as described herein. The present disclosure also relates to compositions containing the compounds having the structure of formula (I) and/or formula (II), and treatment methods in a subject using the compounds and/or compositions.
    Type: Application
    Filed: June 9, 2022
    Publication date: August 29, 2024
    Inventors: Alexander P. SCOPTON, Ross L. CAGAN, Arvin C. DAR, Ernesto GUCCIONE, Alexander RIALDI, Slim MZOUGHI
  • Kinase inhibitor compounds, compositions, and methods of treating cancer
    Patent number: 11066370
    Abstract: The present invention relates to a compound having the structure of formula (I) or a stereoisomer, pharmaceutically acceptable salt, oxide, or solvate thereof, where X, Y, Z, R, R1, R2, R3, R4, R5, and R6 are as described herein. The present invention also relates to compositions containing the compound having the structure of formula (I), and a method of treating cancer in a subject.
    Type: Grant
    Filed: November 14, 2019
    Date of Patent: July 20, 2021
    Assignee: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
    Inventors: Arvin C. Dar, Ross L. Cagan, Alex P. Scopton, Masahiro Sonoshita
  • KINASE INHIBITOR COMPOUNDS, COMPOSITIONS, AND METHODS OF TREATING CANCER
    Publication number: 20200325103
    Abstract: The present invention relates to a compound having the structure of formula (I) or a stereoisomer, pharmaceutically acceptable salt, oxide, or solvate thereof, where X, Y, Z, R, R1, R2, R3, R4, R5, and R6 are as described herein. The present invention also relates to compositions containing the compound having the structure of formula (I), and a method of treating cancer in a subject.
    Type: Application
    Filed: November 14, 2019
    Publication date: October 15, 2020
    Inventors: Arvin C. DAR, Ross L. CAGAN, Alex P. SCOPTON, Masahiro SONOSHITA
  • Kinase inhibitor compounds, compositions, and methods of treating cancer
    Patent number: 10519113
    Abstract: The present invention relates to a compound having the structure of formula (I) or a stereoisomer, pharmaceutically acceptable salt, oxide, or solvate thereof, where X, Y, Z, R, R1, R2, R3, R4, R5, and R6 are as described herein. The present invention also relates to compositions containing the compound having the structure of formula (I), and a method of treating cancer in a subject.
    Type: Grant
    Filed: August 17, 2017
    Date of Patent: December 31, 2019
    Assignee: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
    Inventors: Arvin C. Dar, Ross L. Cagan, Alex P. Scopton, Masahiro Sonoshita
  • KINASE INHIBITOR COMPOUNDS, COMPOSITIONS, AND METHODS OF TREATING CANCER
    Publication number: 20190202789
    Abstract: The present invention relates to a compound having the structure of formula (I) or a stereoisomer, pharmaceutically acceptable salt, oxide, or solvate thereof, where X, Y, Z, R, R1, R2, R3, R4, R5, and R6 are as described herein. The present invention also relates to compositions containing the compound having the structure of formula (I), and a method of treating cancer in a subject.
    Type: Application
    Filed: August 17, 2017
    Publication date: July 4, 2019
    Applicant: Ichan School of Medicine at Mount Sinal
    Inventors: Arvin C. DAR, Ross L. CAGAN, Alex P. SCOPTON, Masahiro SONOSHITA
  • Substituted pyrazolo[3,4-D]pyrimidines and uses thereof
    Patent number: 9895373
    Abstract: Presented herein are novel therapeutic compounds and methods of using the same for the treatment of cancers.
    Type: Grant
    Filed: March 23, 2016
    Date of Patent: February 20, 2018
    Assignees: The Regents of the University of California, Icahn School of Medicine at Mount Sinai
    Inventors: Arvin C. Dar, Tirtha K. Das, Martin Sos, Trever G. Bivona, Kevan M. Shokat, Ross L. Cagan
  • SUBSTITUTED PYRAZOLO[3,4-D]PYRIMIDINES AND USES THEREOF
    Publication number: 20160354377
    Abstract: Presented herein are novel therapeutic compounds and methods of using the same for the treatment of cancers.
    Type: Application
    Filed: March 23, 2016
    Publication date: December 8, 2016
    Inventors: Arvin C. Dar, Tirtha K. Das, Martin Sos, Trever G. Bivona, Kevan M. Shokat, Ross L. Cagan
  • Substituted pyrazolo[3,4-D]pyrimidines and uses thereof
    Patent number: 9321772
    Abstract: Presented herein are novel therapeutic compounds and methods of using the same for the treatment of cancers.
    Type: Grant
    Filed: February 25, 2014
    Date of Patent: April 26, 2016
    Assignees: The Regents of the University of California, Icahn School of Medicine at Mount Sinai
    Inventors: Arvin C. Dar, Tirtha K. Das, Martin Sos, Trever G. Bivona, Kevan M. Shokat, Ross L. Cagan
  • SUBSTITUTED PYRAZOLO[3,4-D]PYRIMIDINES AND USES THEREOF
    Publication number: 20140243357
    Abstract: Presented herein are novel therapeutic compounds and methods of using the same for the treatment of cancers.
    Type: Application
    Filed: February 25, 2014
    Publication date: August 28, 2014
    Applicants: Mount Sinai School of Medicine, The Regents of the University of California
    Inventors: Arvin C. Dar, Tirtha K. Das, Martin Sos, Trever G. Bivona, Kevan M. Shokat, Ross L. Cagan