Patents by Inventor Arye Shteyer

Arye Shteyer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Osteogenic growth oligopeptides as stimulants of hematopoiesis
    Publication number: 20050004037
    Abstract: The present invention relates to a pharmaceutical composition comprising as an effective ingredient an oligopeptide identical or analogous to the C-terminal portion of OGP, having stimulatory activity on the production of hematopoietic cells. Preferred oligopeptides that are used are Tyr-Gly-Phe-Gly-Gly, Tyr-Gly-Phe-His-Gly, Gly-Phe-Gly-Gly or Met-Tyr-Gly-Phe-Gly-Gly. More specifically, these oligopeptides enhance the engraftment of bone marrow transplants, hemopoietic reconstruction, bone marrow re-population and peripheral stem cell mobilization, preferably after chemotherapy or irradiation. The invention further provides methods of treatment and for using these oligopeptides in the preparation of pharmaceutical compositions.
    Type: Application
    Filed: January 29, 2004
    Publication date: January 6, 2005
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventors: Itai Bab, Michael Chorev, Arye Shteyer, Andras Muhlrad, Nura Mansur, Olga Gurevitch, Zvi Greenberg, Sergio Rosini, Silvia Trasciatti, Mario Petrini
  • Osteogenic growth polypeptides identified from regenerating bone marrow
    Patent number: 5461034
    Abstract: A biochemically pure polypeptide(s), termed osteogenic growth polypeptide (OGP), which exhibits stimulatory effects on osteoblastic cells, in vivo bone formation and hemopoietic reconstruction. OGP, identified from regenerating bone marrow, has an amino acid sequence ofAla-Leu-Lys-Arg-Gln-Gly-Arg-Thr-Leu-Tyr-Gly-Phe-Gly-Gly.
    Type: Grant
    Filed: June 18, 1993
    Date of Patent: October 24, 1995
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventors: Gideon A. Rodan, John W. Jacobs, Mohinder K. Sardana, Dan Gazit, Michael Chorev, Andras Muhlrad, Arye Shteyer, Nura Mansur, Zvi Greenberg, Shimon Slavin, Olga Gurevitch, Itai A. Bab