Patents by Inventor Asa Hatami

Asa Hatami has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL ZINC FINGER PROTEIN TRANSCRIPTION FACTORS FOR REPRESSING ALPHA-SYNUCLEIN EXPRESSION
    Publication number: 20240018203
    Abstract: The present disclosure provides zinc finger fusion proteins that inhibit expression of alpha-synuclein in the nervous system, and methods of using the proteins to treat Parkinsons disease, Lewy body dementia, multiple system atrophy, Alzheimers disease, and other neurodegenerative diseases.
    Type: Application
    Filed: October 1, 2021
    Publication date: January 18, 2024
    Applicant: Sangamo Therapeutics, Inc.
    Inventors: Asa Hatami, Bryan Zeitler, Lei Zhang, David Emanuel Paschon
  • ZINC FINGER PROTEIN TRANSCRIPTION FACTORS FOR REPRESSING TAU EXPRESSION
    Publication number: 20230242602
    Abstract: The present disclosure provides zinc finger fusion proteins that inhibit expression of tau in the nervous system, and methods of using the proteins to treat neurodegenerative diseases such as Alzheimer's disease, frontotemporal dementia, and other tauopathies.
    Type: Application
    Filed: January 22, 2021
    Publication date: August 3, 2023
    Applicant: Sangamo Therapeutics, Inc.
    Inventors: Bryan Zeitler, Asa Hatami, Lei Zhang
  • Zinc Finger Protein Transcription Factors for Repressing Alpha-Synuclein Expression
    Publication number: 20220324928
    Abstract: The present disclosure provides zinc finger fusion proteins that inhibit expression of alpha-synuclein in the nervous system, and methods of using the proteins to treat Parkinson's disease, Lewy body dementia, multiple system atrophy, Alzheimer's disease, and other neurodegenerative diseases.
    Type: Application
    Filed: October 2, 2020
    Publication date: October 13, 2022
    Applicant: Sangamo Therapeutics, Inc.
    Inventors: Asa Hatami, Bryan Zeitler, Lei Zhang, David Emanuel Paschon
  • 3D-exoquant method for the analysis of surface molecules and quantification of tissue-specific exosomes in biological fluids
    Patent number: 11243215
    Abstract: In various embodiments methods are provided for identifying and/or quantifying one or more antigens of interest (biomarkers) on the surface of cell- or tissue-specific exosomes.
    Type: Grant
    Filed: January 13, 2017
    Date of Patent: February 8, 2022
    Assignee: The Regents of the University of California
    Inventors: Varghese John, Jesus Campagna, Tina Bilousova, Patricia R. Spilman, Peter James Heinzelman, Asa Hatami, Mohammad Parvez Alam
  • 3D-EXOQUANT METHOD FOR THE ANALYSIS OF SURFACE MOLECULES AND QUANTIFICATION OF TISSUE-SPECIFIC EXOSOMES IN BIOLOGICAL FLUIDS
    Publication number: 20190025330
    Abstract: In various embodiments methods are provided for identifying and/or quantifying one or more antigens of interest (biomarkers) on the surface of cell- or tissue-specific exosomes.
    Type: Application
    Filed: January 13, 2017
    Publication date: January 24, 2019
    Inventors: Varghese John, Jesus Campagna, Tina Bilousova, Patricia R. Spilman, Peter James Heinzelman, Asa Hatami, Mohammad Parvez Alam