Patents by Inventor Asad Khanmohammed

Asad Khanmohammed has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Lipid nanoparticles for delivering mRNA vaccines
    Patent number: 12239735
    Abstract: Provided are novel lipid nanoparticles for delivering nucleic acids such as mRNA. Also provided are methods of making and using lipid nanoparticles for delivering nucleic acids such as mRNA.
    Type: Grant
    Filed: November 7, 2023
    Date of Patent: March 4, 2025
    Assignee: SANOFI
    Inventors: Danilo Casimiro, Sudha Chivukula, Kirill Kalnin, Timothy Plitnik, Timothy Tibbitts, Frank Derosa, Anusha Dias, Rebecca L. Goldman, Hardip Rajeshbhai Gopani, Shrirang Karve, Asad Khanmohammed, Priyal Patel
  • Lipid nanoparticles for delivering mRNA vaccines
    Patent number: 11771653
    Abstract: Provided are novel lipid nanoparticles for delivering nucleic acids such as mRNA. Also provided are methods of making and using lipid nanoparticles for delivering nucleic acids such as mRNA.
    Type: Grant
    Filed: June 30, 2022
    Date of Patent: October 3, 2023
    Assignee: SANOFI
    Inventors: Danilo Casimiro, Sudha Chivukula, Kirill Kalnin, Timothy Plitnik, Timothy Tibbitts, Frank Derosa, Anusha Dias, Rebecca L. Goldman, Hardip Rajeshbhai Gopani, Shrirang Karve, Asad Khanmohammed, Priyal Patel
  • Lipid nanoparticles for delivering mRNA vaccines
    Patent number: 11771652
    Abstract: Provided are novel lipid nanoparticles for delivering nucleic acids such as mRNA. Also provided are methods of making and using lipid nanoparticles for delivering nucleic acids such as mRNA.
    Type: Grant
    Filed: November 5, 2021
    Date of Patent: October 3, 2023
    Assignee: SANOFI
    Inventors: Danilo Casimiro, Sudha Chivukula, Kirill Kalnin, Timothy Plitnik, Timothy Tibbitts, Frank Derosa, Anusha Dias, Rebecca L. Goldman, Hardip Rajeshbhai Gopani, Shrirang Karve, Asad Khanmohammed, Priyal Patel
  • IMPROVED PROCESS OF PREPARING MRNA-LOADED LIPID NANOPARTICLES
    Publication number: 20220218612
    Abstract: The present invention provides an improved process for lipid nanoparticle formulation and mRNA encapsulation. In some embodiments, the present invention provides a process for enhanced encapsulation of messenger RNA (mRNA) in lipid nanoparticles comprising a step of heating the mRNA-encapsulated lipid nanoparticles in a drug product formulation solution.
    Type: Application
    Filed: May 14, 2020
    Publication date: July 14, 2022
    Inventors: Shrirang Karve, Frank DeRosa, Michael Hearlein, Ashish Sarode, Zarna Patel, Rebecca L. Ball, Natalia Vargas Montoya, Priyal Patel, Asad Khanmohammed
  • Lipid Nanoparticle Formulations for mRNA Delivery
    Publication number: 20210353556
    Abstract: The present invention provides, among other things, methods of encapsulating messenger RNA in lipid nanoparticles without the use of flammable solvents, and compositions produced by these methods, for mRNA delivery in therapeutic use. The present invention is, in part, based on the surprising discovery that mRNA can be encapsulated with high efficiency, without using an ethanol solvent, in the presence of an amphiphilic polymer. Thus, the present invention provides safe, cost-effective, and efficient methods of producing LNP formulations from large scale manufacturing processes as well as in low volume formulations for therapeutic applications.
    Type: Application
    Filed: May 14, 2021
    Publication date: November 18, 2021
    Inventors: Shrirang Karve, Frank DeRosa, Natalia Vargas Montoya, Asad Khanmohammed