Patents by Inventor Asami Ohashi

Asami Ohashi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200031932
    Abstract: The present invention provides an anti-PD-L1 antibody capable of staining tumor cells such as melanoma cells. An anti-PD-L1 antibody comprising (a) a light chain comprising CDR1 having the amino acid sequence of KSISKY (SEQ ID NO: 1), CDR2 having the amino acid sequence of SGS and CDR3 having the amino acid sequence of QQHNEYPLT (SEQ ID NO: 2) and (b) a heavy chain comprising CDR1 having the amino acid sequence of GYTFTDYI (SEQ ID NO: 3), CDR2 having the amino acid sequence of INPDSGGN (SEQ ID NO: 4) and CDR3 having the amino acid sequence of ARGITMMVVISHWKFDF (SEQ ID NO: 5). A composition for detecting PD-L1, comprising the above antibody as an active ingredient. A method for preparing the above antibody is also provided.
    Type: Application
    Filed: March 23, 2018
    Publication date: January 30, 2020
    Inventors: Satoru Konnai, Kazuhiko Ohashi, Shiro Murata, Tomohiro Okagawa, Asami Nishimori, Naoya Maekawa, Satoshi Takagi, Yumiko Kagawa, Yasuhiko Suzuki, Chie Nakajima
  • Publication number: 20200015400
    Abstract: ‘Tochigi i37 Go’ is a new variety of strawberry bred by crossbreeding variety ‘Tochigi 32 Go’ and ‘09-48-5’ in 2012. The plant may be used, e.g., for cultivation of fruit for consumption. ‘Tochigi i37 Go’ is a high-quality, high-yielding variety having early maturing and high-yielding characteristic, fruit with a taste similar to those of ‘Tochiotome’, a large fruit size, a firm fruit firmness, and adaptability to forcing culture.
    Type: Application
    Filed: April 5, 2019
    Publication date: January 9, 2020
    Inventors: Kobayashi Yasuhiro, Takashi Shigeno, Takashi Ohashi, Akitsugu Hatakeyama, Kazunari Iimura, Tatsuro Nakanishi, Masaaki Ueki, Akina Toyoda, Asami Nagashima, Yoshinori Saito, Risa Tsurumi, Natsumi Kojima, Yukio Ohashi
  • Publication number: 20190185568
    Abstract: The present invention provides an anti-PD-1 antibody capable of repeated administration even to animals other than rat. An anti-PD-1 antibody comprising (a) a light chain comprising a light chain variable region containing CDR1 having the amino acid sequence of QSLEYSDGYTY (SEQ ID NO: 16), CDR2 having the amino acid sequence of GVS and CDR3 having the amino acid sequence of FQATHDPDT (SEQ ID NO: 17) and the light chain constant region of an antibody of an animal other than rat; and (b) a heavy chain comprising a heavy chain variable region containing CDR1 having the amino acid sequence of GFSLTSYY (SEQ ID NO: 18), CDR2 having the amino acid sequence of IRSGGST (SEQ ID NO: 19) and CDR3 having the amino acid sequence of ARTSSGYEGGFDY (SEQ ID NO: 20) and the heavy chain constant region of an antibody of an animal other than rat. A pharmaceutical composition comprising the above-described anti-PD-1 antibody as an active ingredient. A method for preparing the anti-PD-1 antibody is also provided.
    Type: Application
    Filed: August 10, 2017
    Publication date: June 20, 2019
    Inventors: Satoru Konnai, Kazuhiko Ohashi, Shiro Murata, Tomohiro Okagawa, Asami Nishimori, Naoya Maekawa, Yasuhiko Suzuki, Chie Nakajima
  • Publication number: 20190169294
    Abstract: The present invention provides an anti-LAG-3 antibody capable of repeated administration even to animals other than rat. An anti-LAG-3 antibody comprising (a) a light chain comprising a light chain variable region containing CDR1 having the amino acid sequence of QSLLDSDGNTY (SEQ ID NO: 16), CDR2 having the amino acid sequence of SVS and CDR3 having the amino acid sequence of MQATHVPFT (SEQ ID NO: 17) and the light chain constant region of an antibody of an animal other than rat; and (h) a heavy chain comprising a heavy chain variable region containing CDR1 having the amino acid sequence of GFDFDTYP (SEQ ID NO: 18), CDR2 having the amino acid sequence of ITIKTHNYAT (SEQ ID NO: 19) and CDR3 having the amino acid sequence of NREDFDY (SEQ ID NO: 20) and the heavy chain constant region of an antibody of an animal other than rat. A pharmaceutical composition comprising the above anti-LAG-3 antibody as an active ingredient. A method for preparing the above anti-LAG-3 antibody is also provided.
    Type: Application
    Filed: August 10, 2017
    Publication date: June 6, 2019
    Inventors: Satoru Konnai, Kazuhiko Ohashi, Shiro Murata, Tomohiro Okagawa, Asami Nishimori, Naoya Maekawa, Yasuhiko Suzuki, Chie Nakajima
  • Patent number: 10050306
    Abstract: An electrolyte containing a non-aqueous solvent, a lithium salt (A) and at least one compound (B) selected from the group consisting of a compound represented by the following formula (1), a compound represented by the following formula (2) and a compound having a constitutional unit represented by the following formula (3a) and a constitutional unit represented by the following formula (3b).
    Type: Grant
    Filed: September 30, 2014
    Date of Patent: August 14, 2018
    Assignee: ASAHI KASEI KABUSHIKI KAISHA
    Inventors: Shinya Hamasaki, Fumiaki Ozaki, Yusuke Shigemori, Masato Murakami, Asami Ohashi
  • Patent number: 9997805
    Abstract: An electrolyte containing a non-aqueous solvent, a lithium salt (A) and at least one compound (B) selected from the group consisting of a compound represented by the following formula (1), a compound represented by the following formula (2) and a compound having a constitutional unit represented by the following formula (3a) and a constitutional unit represented by the following formula (3b).
    Type: Grant
    Filed: September 30, 2014
    Date of Patent: June 12, 2018
    Assignee: ASAHI KASEI KABUSHIKI KAISHA
    Inventors: Shinya Hamasaki, Fumiaki Ozaki, Yusuke Shigemori, Masato Murakami, Asami Ohashi
  • Publication number: 20160240888
    Abstract: An electrolyte containing a non-aqueous solvent, a lithium salt (A) and at least one compound (B) selected from the group consisting of a compound represented by the following formula (1), a compound represented by the following formula (2) and a compound having a constitutional unit represented by the following formula (3a) and a constitutional unit represented by the following formula (3b).
    Type: Application
    Filed: September 30, 2014
    Publication date: August 18, 2016
    Applicant: ASAHI KASEI KABUSHIKI KAISHA
    Inventors: Shinya HAMASAKI, Fumiaki OZAKI, Yusuke SHIGEMORI, Masato MURAKAMI, Asami OHASHI
  • Patent number: 9118088
    Abstract: The present invention provides an electrolyte solution and a lithium ion secondary battery which maintain for a long period high battery characteristics represented by the discharge capacity retention rate after the charge/discharge cycle, and simultaneously achieve also the high safety represented by the flame retardation. The present invention provides an electrolyte solution containing a nonaqueous solvent, an electrolyte, a specific compound having a perfluoroalkyl group in the molecule, and an additive having a fluorine atom and/or a phosphorus atom in the molecule.
    Type: Grant
    Filed: June 9, 2010
    Date of Patent: August 25, 2015
    Assignee: ASAHI KASEI E-MATERIALS CORPORATION
    Inventors: Asami Ohashi, Yoshiyuki Ishii
  • Patent number: 8399136
    Abstract: The electrolyte solution for a lithium ion secondary battery according to the present invention contains a nonaqueous solvent, a lithium salt and a compound represented by the general formula (Z) shown below. Thereby, a lithium ion secondary battery having high battery characteristics and simultaneously achieving a high safety as well can be provided. R—SO2—Ar1—O—R1??(Z) wherein Ar1 denotes a substituted or nonsubstituted divalent aromatic group having 5 to 30 atoms of the nucleus(es); R1 denotes a saturated or unsaturated monovalent hydrocarbon group having 1 to 20 carbon atoms; and R denotes a saturated or unsaturated monovalent hydrocarbon group having a perfluoroalkyl group and having 2 to 22 carbon atoms.
    Type: Grant
    Filed: August 8, 2011
    Date of Patent: March 19, 2013
    Assignees: Asahi Kasei E-Materials Corporation, Yamaguchi University
    Inventors: Asami Ohashi, Yoshiyuki Ishii, Hiroaki Okamoto, Yuki Morita
  • Publication number: 20120141878
    Abstract: The present invention provides an electrolyte solution and a lithium ion secondary battery which maintain for a long period high battery characteristics represented by the discharge capacity retention rate after the charge/discharge cycle, and simultaneously achieve also the high safety represented by the flame retardation. The present invention provides an electrolyte solution containing a nonaqueous solvent, an electrolyte, a specific compound having a perfluoroalkyl group in the molecule, and an additive having a fluorine atom and/or a phosphorus atom in the molecule.
    Type: Application
    Filed: June 9, 2010
    Publication date: June 7, 2012
    Applicant: ASAHI KASEI E-MATERIALS CORPORATION
    Inventors: Asami Ohashi, Yoshiyuki Ishii
  • Publication number: 20120009480
    Abstract: The electrolyte solution for a lithium ion secondary battery according to the present invention contains a nonaqueous solvent, a lithium salt and a compound represented by the general formula (Z) shown below. Thereby, a lithium ion secondary battery having high battery characteristics and simultaneously achieving a high safety as well can be provided. R—SO2—Ar1—O—R1??(Z) wherein Ar1 denotes a substituted or nonsubstituted divalent aromatic group having 5 to 30 atoms of the nucleus(es); R1 denotes a saturated or unsaturated monovalent hydrocarbon group having 1 to 20 carbon atoms; and R denotes a saturated or unsaturated monovalent hydrocarbon group having a perfluoroalkyl group and having 2 to 22 carbon atoms.
    Type: Application
    Filed: August 8, 2011
    Publication date: January 12, 2012
    Applicants: YAMAGUCHI UNIVERSITY, ASAHI KASEI E-MATERIALS CORPORATION
    Inventors: Asami OHASHI, Yoshiyuki ISHII, Hiroaki OKAMOTO, Yuki MORITA
  • Patent number: 7491763
    Abstract: A polyamide composition has (a) a polyamide, (b) at least one phosphorus compound selected from the group consisting of phosphoric acids, phosphorous acids, hypophosphorous acids, metal phosphates, metal phosphites, metal hypophosphites, phosphoric esters, and phosphorous esters, and (c) a soluble metal aluminate compound represented by the general formula (M2O)x(Al2O3)y (wherein X+Y=1 and M is a Group 1 metal of the Periodic Table), wherein the molar ratio of polyvalent metal to monovalent metal in the composition (polyvalent metal/monovalent metal) is from 0.25 to 1.0.
    Type: Grant
    Filed: July 9, 2003
    Date of Patent: February 17, 2009
    Assignee: Asahi Kasei Chemicals Corporation
    Inventors: Masaaki Aramaki, Asami Ohashi
  • Publication number: 20060142443
    Abstract: A polyamide composition has (a) a polyamide, (b) at least one phosphorus compound selected from the group consisting of phosphoric acids, phosphorous acids, hypophosphorous acids, metal phosphates, metal phosphites, metal hypophosphites, phosphoric esters, and phosphorous esters, and (c) a soluble metal aluminate compound represented by the general formula (M2O)x(Al2O3)y (wherein X+Y=1 and M is a Group 1 metal of the Periodic Table), wherein the molar ratio of polyvalent metal to monovalent metal in the composition (polyvalent metal/monovalent metal) is from 0.25 to 1.0.
    Type: Application
    Filed: July 9, 2003
    Publication date: June 29, 2006
    Inventors: Masaaki Aramaki, Asami Ohashi