Patents by Inventor Asami Seino

Asami Seino has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Imidazoyl-.beta.-oxo-.beta.-benzenepropanethiomide derivative, compositions and method of use thereof
    Patent number: 5439927
    Abstract: The .beta.-oxo-.beta.-benzenepropanethioamide derivative of the present invention has potassium channel opening action and is useful for treatment of hypertension, asthma, hypersensitive colon syndrome, and enteritis through pharmacological actions including blood vessel dilation, bronchial tract dilation, relaxation of gastrointestinal tract smooth muscle, and the like. The present invention also includes a pharmaceutical composition containing, as the active ingredient, the compound of the present invention and a method for producing the same.
    Type: Grant
    Filed: April 22, 1994
    Date of Patent: August 8, 1995
    Assignee: Mitsubishi Kasei Corporation
    Inventors: Tetsuo Sekiya, Mikio Tsutsui, Tetsuro Shimpuku, Tatsuo Nagano, Junko Hayashi, Asami Seino
  • .beta.-oxo-.beta.-benzenepropanethioamide compounds
    Patent number: 5332833
    Abstract: The .beta.-oxo-.beta.-benzenepropanethioamide derivative of the present invention has potassium channel opening action and is useful for treatment of hypertension, asthma, hypersensitive colon syndrome, and enteritis through pharmacological actions including blood vessel dilation, bronchial tract dilation, relaxation of gastrointestinal tract smooth muscle, and the like. The present invention also includes a pharmaceutical composition containing, as the active ingredient, the compound of the present invention and a method for producing the same.
    Type: Grant
    Filed: December 23, 1992
    Date of Patent: July 26, 1994
    Assignee: Mitsubishi Kasei Corporation
    Inventors: Tetsuo Sekiya, Mikio Tsutsui, Tetsuro Shimpuku, Tatsuo Nagano, Junko Hayashi, Asami Seino
  • Antihypertensive thiocarbamoylascetonitrile compounds
    Patent number: 5246958
    Abstract: Disclosed are antihypertensive pharmaceutical compositions and compounds which include the thiocarbamoylacetonitrile having the formula: ##STR1## wherein: R.sup.1 is selected from the group consisting of hydrogen, a C.sub.1 to C.sub.6 alkyl, a C.sub.3 to C.sub.6 cycloalkyl or --(CH.sub.2).sub.n --A (where A is selected from the group consisting of a C.sub.6 to C.sub.12 aryl, a 5- or 6-membered heterocyclic group or a fused heterocyclic group constituted by 9 or 10 atoms, each of which may be substituted by at least one substitute group selected from a C.sub.1 to C.sub.6 alkyl and a halogen and n is 0 or an integer of 1 to 6),R.sup.2 represents a C.sub.1 to C.sub.10 alkyl, and Ar represents an aryl, a 5- or 6-membered heterocyclic group or a fused heterocyclic group, each of which may be substituted by at least one substituent group selected from the group consisting of a C.sub.1 to C.sub.6 alkyl, a C.sub.1 to C.sub.6 alkoxy, a C.sub.2 to C.sub.7 alkylcarbonyl, a C.sub.7 to C.sub.
    Type: Grant
    Filed: March 4, 1991
    Date of Patent: September 21, 1993
    Assignee: Mitsubishi Kasei Corporation
    Inventors: Hiromi Okushima, Akihiro Tobe, Makio Kobayashi, Tetsuro Shimpuku, Hideki Bessho, Junko Hayashi, Asami Seino