Patents by Inventor Asami Umeda

Asami Umeda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of assaying substance capable of changing mitochondrial membrane potential
    Patent number: 7781184
    Abstract: The present invention aims to provide a convenient and high precision evaluation method of a pharmaceutical agent that changes the mitochondrial membrane potential, using a mitochondrial membrane potential of a cultured cell as an index. The present invention provides a method for evaluating the ability of a test substance to change the mitochondrial membrane potential by using, as an index, the change in the mitochondrial membrane potential, which is produced by the addition of an ion permeability regulator on a cellular membrane to a cell culture medium, wherein the change is measured as variation in the fluorescent intensity of a fluorescent dye.
    Type: Grant
    Filed: May 18, 2005
    Date of Patent: August 24, 2010
    Assignee: Mitsubishi Tanabe Pharma Corporation
    Inventors: Asami Umeda, Sumiko Nagaki
  • Method Of Assaying Substance Capable Of Changing Mitochondrial Membrane Potential
    Publication number: 20070202486
    Abstract: The present invention aims to provide a convenient and high precision evaluation method of a pharmaceutical agent that changes the mitochondrial membrane potential, using a mitochondrial membrane potential of a cultured cell as an index. The present invention provides a method for evaluating the ability of a test substance to change the mitochondrial membrane potential by using, as an index, the change in the mitochondrial membrane potential, which is produced by the addition of an ion permeability regulator on a cellular membrane to a cell culture medium, wherein the change is measured as variation in the fluorescent intensity of a fluorescent dye.
    Type: Application
    Filed: May 18, 2005
    Publication date: August 30, 2007
    Applicant: Mitsubishi Pharma Corporation
    Inventors: Asami Umeda, Sumiko Nagaki