Patents by Inventor Asayuki Kamatani

Asayuki Kamatani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polymorphic and amorphous forms of 2-{3-[(E)-2-(4,6-dimethyl-pyridin-2-yl)-vinyl]-1H-indazol-6-ylamino}-N-(4-hydroxy-but-2-ynyl)benzamide
    Publication number: 20060160863
    Abstract: This invention provides several crystalline polymorphic forms, amorphous forms, and mixtures thereof of the compound of Formula I: and pharmaceutical compositions made therewith, and to the therapeutic or prophylactic use of such compounds and pharmaceutical compositions, to treat ophthalmic diseases, such as age related macular degeneration and other diseases associated with unwanted ocular angiogenesis.
    Type: Application
    Filed: December 14, 2005
    Publication date: July 20, 2006
    Inventors: Tim Edward Alcacio, Winnie Hoyan Chan, Mark Guzman, Asayuki Kamatani, Cynthia Palmer, Nabil Saeed, Jill Melissa Scott, Jayaram Kasturi Srirangam
  • Process for producing indolopyrrolocarbazole derivative
    Publication number: 20050176968
    Abstract: The present invention provides a process for industrially advantageously producing a compound represented by the formula (I): or a pharmaceutically acceptable salt thereof, which is useful as an anticancer agent, and also provides a catalyst used for hydrogenation reaction in the process.
    Type: Application
    Filed: August 22, 2003
    Publication date: August 11, 2005
    Inventors: Atsushi Akao, Masashi Kawasaki, Asayuki Kamatani, Toshiaki Mase
  • Process for preparing indolopyrrolocarbazole derivatives, intermediates therefor, and preparation process of the intermediates
    Patent number: 6790836
    Abstract: A process for preparing indolopyrrolocarbazole derivatives [I] by trating a compound [V] with a base in an inert solvent to prepare a compound [IV], reacting the compound [IV] with a compound [III]to prepare a compound [II], and deblocking the compound [II]; intermediates [II], [III] and [IV]; and a process for preparing compounds [III]: [wherein Y1 is hydrogen, C1-4 alkyl, phenyl, benzyloxymethyl, or aralkyl; R1, R2, R3, R4, R5, and R6 are each independently a hydroxyl-protecting group; R7 and R8 are each independently hydrogen or a hydroxyl-protecting group; and X is an acid molecule]. The above process is a safe and easy industrial process for preparing indolopyrrolocarbazole derivatives [1] useful as antitumor agents.
    Type: Grant
    Filed: August 6, 2002
    Date of Patent: September 14, 2004
    Assignee: Banyu Pharmaceutical Co., Ltd.
    Inventors: Shouichi Hiraga, Masashi Kawasaki, Atsushi Akao, Asayuki Kamatani, Masayuki Hagiwara, Toshiaki Mase, Fumio Nakano
  • Preparation and isolation of indolocarbazole glycosides
    Publication number: 20040116688
    Abstract: The present invention relates to a novel process to make indolocarbazole glycosides in high purity which inhibit the growth of tumor cells and are therefore useful in the treatment of cancer in mammals, and the like.
    Type: Application
    Filed: September 25, 2003
    Publication date: June 17, 2004
    Inventors: Steven Weissman, David Tschaen, Asayuki Kamatani, Shouichi Hiraga, Masashi Kawasaki, Takehiko Iida
  • Preparation and isolation of indolocarbazole glycosides
    Patent number: 6559299
    Abstract: The present invention relates to a novel process to make indolocarbazole glycosides in high purity which inhibit the growth of tumor cells and are therefore useful in the treatment of cancer in mammals, and the like.
    Type: Grant
    Filed: March 21, 2002
    Date of Patent: May 6, 2003
    Assignees: Merck & Co., Inc., Banyu Pharmaceutical Co., Ltd.
    Inventors: Steven Weissman, David Tschaen, Asayuki Kamatani, Shouichi Hiraga, Masashi Kawasaki, Takehiko Iida
  • Process for preparing indolopyrrolocarbazole derivatives, intermediates therefor, and preparation process of the intermediates
    Publication number: 20030060621
    Abstract: This invention relates to a process for preparation of an indolopyrrolocarbazole derivative [I] by treating a compound [V] with a base in an inert solvent to prepare a compound [IV], reacting the obtained compound [IV] with a compound [III] to prepare a compound [II] and then removing the protective groups of the compound [II], the preparation intermediates compound [II], compound [III] and compound [IV], and processes for preparation of the compound [III].
    Type: Application
    Filed: August 6, 2002
    Publication date: March 27, 2003
    Inventors: Shouichi Hiraga, Masashi Kawasaki, Atsushi Akao, Asayuki Kamatani, Masayuki Hagiwara, Toshiaki Mase, Fumio Nakano
  • Preparation and isolation of indolocarbazole glycosides
    Publication number: 20020193324
    Abstract: The present invention relates to a novel process to make indolocarbazole glycosides in high purity which inhibit the growth of tumor cells and are therefore useful in the treatment of cancer in mammals, and the like.
    Type: Application
    Filed: March 21, 2002
    Publication date: December 19, 2002
    Inventors: Steven Weissman, David Tschaen, Asayuki Kamatani, Shouichi Hiraga, Masashi Kawasaki, Takehiko Iida