Patents by Inventor Ashique Rafique

Ashique Rafique has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • High affinity antibodies to human IL-6 receptor
    Publication number: 20070280945
    Abstract: A human antibody or an antigen-binding fragment which binds human IL-6 receptor (hIL-6R) with a KD of about 500 pM or less and blocks IL-6 activity with an IC50 of 200 pM or less. In preferred embodiments, the antibody the antibody or antigen-binding fragment binds hIL-6R with an affinity at least 2-fold higher relative to its binding monkey IL-6R.
    Type: Application
    Filed: June 1, 2007
    Publication date: December 6, 2007
    Inventors: Sean Stevens, Tammy Huang, Joel Martin, Jeanette Fairhurst, Ashique Rafique, Eric Smith, Kevin Pobursky, Nicholas Papadopoulos, James Fandl, Gang Chen, Margaret Karow