Abstract: The present disclosure discloses a herbal composition comprising herbal composition comprising a Vitex negundo aqueous leaf extract powder; a supercritical CO2 Zingiber officinale rhizome oleoresin; and pharmaceutical acceptable carrier wherein the ratio of Vitex negundo aqueous leaf extract powder to supercritical CO2 Zingiber officinale rhizome oleoresin to pharmaceutical acceptable carrier is in the range of 80:20:0 to 89:9:2. The present disclosure also discloses a process of preparation of a herbal composition. The present herbal composition is clinically proven effective for reducing acute or chronic musculoskeletal pain, alleviating physical-activity induced joint pain such as mechanical loads on joints, reducing exercise-induced knee joint pain and chronic non-specific low back pain and related dysfunction.

Abstract: Systems and methods disclosed provide a laser-assisted micro-mass spectrometer, which can include a pulsed inlet, a multi-wavelength laser system, and a first mass spectrometer module including a plurality of first ionization sources. In an embodiment, the pulsed inlet can be configured to receive a neutral sample of analyte material and provide it to said first mass spectrometer module.

Abstract: A fluid chromatography device, comprising a first segment of a column configured to connect with an inlet that is configured to receive a fluid sample. The fluid chromatography device includes a second segment of the column in fluid communication with the first segment at a connection and an in-line exhaust in fluid communication with the first segment at the connection between the first and second segments. The in-line exhaust vents the fluid sample from the first segment until closed. The in-line exhaust closes after a period of time after a sample is injected into the first segment. The flow rate of the fluid sample of the first segment before the in-line exhaust closes is higher than a flow rate of the fluid sample of the first and second segments after the in-line exhaust closes.

Abstract: The disclosure includes an outer electrode and an inner electrode. The outer electrode defines an inner volume and is configured to receive injected electrons through at least one aperture. The inner electrode positioned in the inner volume. The outer electrode and inner electrode are configured to confine the received electrons in orbits around the inner electrode in response to an electric potential between the outer electrode and the inner electrode. The apparatus does not include a component configured to generate an electron-confining magnetic field.

Abstract: Systems and methods disclosed provide a laser-assisted micro-mass spectrometer, which can include a pulsed inlet, a multi-wavelength laser system, and a first mass spectrometer module including a plurality of first ionization sources. In an embodiment, the pulsed inlet can be configured to receive a neutral sample of analyte material and provide it to said first mass spectrometer module.

Abstract: The disclosure includes an ionization chamber, a first electron multiplier, and a second electron multiplier. The ionization chamber is configured to receive gas molecules from an environment at a pressure. The first electron multiplier is configured to receive a plurality of photons from a photon source, generate a first plurality of electrons from the plurality of photons, and discharge the first plurality of electrons into the ionization chamber to generate a plurality of gas ions from at least a portion of the gas molecules. The second electron multiplier is configured to receive the plurality of gas ions from the ionization chamber and generate a second plurality of electrons from the plurality of gas ions that is proportional to a quantity of the plurality of gas ions. A quantity of electrons of the second plurality of electrons is indicative of the pressure.

Abstract: Systems and methods for Deep Learning techniques based multi-purpose conversational agents for processing natural language queries. The traditional systems and methods provide for conversational systems for processing natural language queries but do not employ Deep Learning techniques, and thus are unable to process large number of intents. Embodiments of the present disclosure provide for Deep Learning techniques based multi-purpose conversational agents for processing the natural language queries by defining and logically integrating a plurality of components comprising of multi-purpose conversational agents, identifying an appropriate agent to process one or more natural language queries by a High Level Intent Identification technique, predicting a probable user intent, classifying the query, and generate a set of responses by querying or updating one or more knowledge graphs.

Abstract: The disclosure includes an outer electrode and an inner electrode. The outer electrode defines an inner volume and is configured to receive injected electrons through at least one aperture. The inner electrode positioned in the inner volume. The outer electrode and inner electrode are configured to confine the received electrons in orbits around the inner electrode in response to an electric potential between the outer electrode and the inner electrode. The apparatus does not include a component configured to generate an electron-confining magnetic field.

Abstract: The disclosure includes an ionization chamber, a first electron multiplier, and a second electron multiplier. The ionization chamber is configured to receive gas molecules from an environment at a pressure. The first electron multiplier is configured to receive a plurality of photons from a photon source, generate a first plurality of electrons from the plurality of photons, and discharge the first plurality of electrons into the ionization chamber to generate a plurality of gas ions from at least a portion of the gas molecules. The second electron multiplier is configured to receive the plurality of gas ions from the ionization chamber and generate a second plurality of electrons from the plurality of gas ions that is proportional to a quantity of the plurality of gas ions. A quantity of electrons of the second plurality of electrons is indicative of the pressure.

Abstract: Systems and methods for Deep Learning techniques based multi-purpose conversational agents for processing natural language queries. The traditional systems and methods provide for conversational systems for processing natural language queries but do not employ Deep Learning techniques, and thus are unable to process large number of intents. Embodiments of the present disclosure provide for Deep Learning techniques based multi-purpose conversational agents for processing the natural language queries by defining and logically integrating a plurality of components comprising of multi-purpose conversational agents, identifying an appropriate agent to process one or more natural language queries by a High Level Intent Identification technique, predicting a probable user intent, classifying the query, and generate a set of responses by querying or updating one or more knowledge graphs.

Abstract: A dual-ionization mass spectrometer includes a first mass spectrometer module forming a hard ionization mass spectrometer, a second mass spectrometer forming a soft ionization mass spectrometer, a vacuum ultraviolet light source positioned between the first and second modules, a housing encompassing the first and second sets of plates and the light source, and an inlet positioned to receive a sample of an analyte and provide it to at least one of the sets of plates. A method of detecting a substance includes receiving a sample of an analyte into a housing through an inlet, performing soft ionization mass spectrometry on the sample with a soft ionization mass spectrometer in the housing, performing hard ionization spectrometry on the sample with a hard ionization spectrometer in the housing if needed, and generating a detection result from at least one of the soft ionization spectrometry and the hard ionization spectrometry.

Abstract: A dual-ionization mass spectrometer includes a first mass spectrometer module forming a hard ionization mass spectrometer, a second mass spectrometer forming a soft ionization mass spectrometer, a vacuum ultraviolet light source positioned between the first and second modules, a housing encompassing the first and second sets of plates and the light source, and an inlet positioned to receive a sample of an analyte and provide it to at least one of the sets of plates. A method of detecting a substance includes receiving a sample of an analyte into a housing through an inlet, performing soft ionization mass spectrometry on the sample with a soft ionization mass spectrometer in the housing, performing hard ionization spectrometry on the sample with a hard ionization spectrometer in the housing if needed, and generating a detection result from at least one of the soft ionization spectrometry and the hard ionization spectrometry.

Abstract: A planar ion funnel is disclosed that can be used for ion control. In one application, the planar ion funnel can be used for ion control in a mass spectrometer. The planar ion funnel can be formed on a surface of a substantially planar substrate including an orifice. An electrically conductive structure can be formed on a top surface of the substrate that surrounds the orifice. In operation, a power can be applied to the conductive structure that causes an electric field to be generated that draws ions into and through the orifice. In one embodiment, the orifice can be circular and the conductive structure can be a series of nested rings of increasing diameter surrounding the orifice.

Abstract: A hydraulically set packer assembly actuated over an electronic line. The assembly includes a hydraulic packer setting mechanism that serves as an intensifier that is activated by way of an electronic trigger. As such, the trigger may be electronically coupled to an electronic line that is conventionally available for surface communications between surface equipment and a downhole gauge. The gauge generally present for monitoring well conditions such as pressure. Thus, a separate dedicated hydraulic or other powering line need not be outfitted as part of the assembly. Once more, for sake of gauge and well monitoring integrity, communications with the setting mechanism may be severed upon setting of the packer.

Abstract: A hydraulically set packer assembly actuated over an electronic line. The assembly includes a hydraulic packer setting mechanism that serves as an intensifier that is activated by way of an electronic trigger. As such, the trigger may be electronically coupled to an electronic line that is conventionally available for surface communications between surface equipment and a downhole gauge. The gauge generally present for monitoring well conditions such as pressure. Thus, a separate dedicated hydraulic or other powering line need not be outfitted as part of the assembly. Once more, for sake of gauge and well monitoring integrity, communications with the setting mechanism may be severed upon setting of the packer.

Abstract: A die assembly for creating a ring electrode including a cylindrically-shaped die base, two die walls and a die top sized to fit inside a cylindrical die housing. The die base and die top having a series of concentric elevations used as impressions to form on two ends of the ring electrode. A method of fabricating an LTCC ring electrode using the die assembly is also provided.

Abstract: To communicate measurement data from a well, data corresponding to measurement data collected by multiple sensors in a well is transformed downhole and passed to an intermediate communications device, which device in turn passes a subset of that data to a destination communications device. The destination communications device applies a second transformation to the data received from the intermediate communications device. The first and second transformations are designed such that meaningful data can be recovered at the destination communications device even though only a subset of the original transformed data has been received.

Abstract: A cylindrical ion trap (CIT) mass spectrometer constructed using a non-conductive substrate (LTCC) as the basis for the ring electrode. Photolithography and electroless plating were used to create well-defined conductive areas on the LTCC ring electrode. The inventive method allows for the precise control of establishing conductive areas on a non-conductive substrate through the steps of punching, lamination, firing, metallization and photolithography on the metallized layer.