Abstract: Embodiments disclosed herein provide devices, systems, and methods for instrument exchanges during ophthalmic surgery. More particularly, the present disclosure relates to valved cannula assemblies and methods of use thereof. A valved cannula assembly includes a cannula having a head at a proximal end of the cannula and a hollow rod extending from the head to a distal end of the cannula. The valved cannula assembly includes a valved hub coupled to the head and including a septum having two or more curved flaps configured to provide an opening for an instrument.

Abstract: A machine-learned predictive model is trained to predict potential for customer complaint. The model is part of an online concierge system. The online concierge system accesses a customer order that includes one or more items. The online concierge system determines input data for an item of the one or more items. The online concierge system determines a prediction value associated with potential for customer complaint for the item by applying the machine-learned prediction model to the input data. The online concierge system provides the prediction value to a picker client device associated with a picker who is assigned the item. The picker client device presents an alert to the picker based in part on the prediction value, and the alert includes a message that is customized to mitigate a cause of potential customer complaint for the item.

Abstract: Certain aspects of the present disclosure generally relate to ophthalmic surgery, and more particularly, to methods and apparatuses for controlling intraocular pressure (IOP) and administering ocular tamponades during or after ophthalmic surgery. An exemplary apparatus generally includes a proximal segment having a first inner diameter (ID), a first proximal end, and a first distal end. The apparatus further includes a distal segment having a second ID smaller than the first ID, a second proximal end, and a second distal end configured to be disposed inside a hub or a cannula transition of a valved cannula comprising the hub, a shaft, and the cannula transition between the hub and the shaft.

Abstract: An online system receives a request to confirm a transaction that is associated with an order. The system accepts or declines the transaction based on whether an amount associated with the pending transaction is likely to exceed an expected amount of the order by more than a threshold value. To determine the threshold, the system trains a first model to predict an overspend for an order and then trains a second model to predict an amount of error associated with the predictions from the first model. The outputs of the first model and the second model provide a mean and a variance for an expected distribution of the overspend. If the actual overspend amount for the transaction exists in too high of a percentile of the distribution, the transaction may be flagged for review or declined.

Abstract: Certain aspects of the present disclosure generally relate to ophthalmic surgery, and more particularly, to methods and apparatuses for controlling intraocular pressure (IOP) and administering ocular tamponades during or after ophthalmic surgery. An exemplary apparatus generally includes a proximal segment having a first inner diameter (ID), a first proximal end, and a first distal end. The apparatus further includes a distal segment having a second ID smaller than the first ID, a second proximal end, and a second distal end configured to be disposed inside a hub or a cannula transition of a valved cannula comprising the hub, a shaft, and the cannula transition between the hub and the shaft.

Abstract: An online concierge system receives, from a client device associated with a user of the online concierge system, order data associated with an order placed with the online concierge system, in which the order data describes a delivery location for the order. The online concierge system receives information describing a set of attributes associated with the delivery location and accesses a machine learning model trained to predict a difference between an arrival time and a delivery time for the delivery location. The online concierge system applies the model to the set of attributes associated with the delivery location to predict the difference between the arrival time and the delivery time for the delivery location and determines an estimated delivery time for the order based at least in part on the predicted difference. The online concierge system sends the estimated delivery time for the order for display to the client device.

Abstract: Certain aspects of the present disclosure generally relate to ophthalmic surgery, and more particularly, to methods and apparatuses for controlling intraocular pressure (IOP). An exemplary apparatus generally includes a proximal segment comprising a first inner diameter (ID), an intermediate segment coupled to the proximal segment, the intermediate segment comprising a second ID smaller than the first ID, and a distal segment coupled to the intermediate segment, the distal segment comprising a third ID smaller than the second ID.

Abstract: An online concierge system receives data points associated with picking up and delivering orders and arriving at retailer/delivery locations from picker client devices and executes a clustering process on one or more sets of the data points. The system determines a geolocation associated with each location based on the clustering process and identifies one or more points of interest associated with each location based on rules applied to the data points. The system receives information describing an order, identifies pairs of data points associated with a location associated with the order, and determines a navigation path including a sequence of points of interest for servicing the order based on points of interest associated with the location and a difference between times associated with each pair of data points. The system sends the geolocation and navigation path to a picker client device associated with a picker servicing the order.

Abstract: Certain embodiments herein disclose a cannula assembly. The cannula assembly comprises a cannula, having a proximal end and a distal end. The cannula comprises a head at the proximal end, the head having one or more wings. The cannula also comprises a hollow rod extending from the head to the distal end. The cannula assembly also comprises a hub couplable to the head and having a housing with an inner wall. The inner wall comprises an undercut, and one or more distal ends of the corresponding one or more wings are configured to fit into the undercut and couple the hub to the head upon insertion of the head into the hub.

Abstract: A trocar-cannula insertion tool for ophthalmic procedures may include a cap with a body having a proximal end and a distal end opposite the proximal end. A marking element extends in a distal direction from the distal end of the body and includes at least one marking tip for forming one or more indentations on a patient's eye during an ophthalmic procedure. A manipulation element extends from the body in a direction different from the marking element and includes at least one manipulation tip for gripping a tissue of the patient's eye during the ophthalmic procedure. The cap may further include at least one window for exposing a photoluminescent cannula of the trocar-cannula insertion tool to light, enabling the cannula to absorb photons prior to insertion thereof.

Abstract: Embodiments disclosed herein relate to an infusion cannula for infusion/venting of fluids to/from the eye to control intraocular pressure. The infusion cannula includes a tubular body with a tubular inlet located at a proximal end of the tubular body and a tubular outlet located at a distal end of the tubular body. The tubular outlet is aligned with a first longitudinal axis and configured to extend through a septum of a valved cannula hub. The infusion cannula includes a retention piece extending from or coupled to the tubular body. The retention piece has an annular body surrounding the tubular body at the distal end of the tubular body and configured to be coupled to the valved cannula hub. An inner surface of the annular body has a profile configured to form a snap fit with an overhang formed along an outer surface of the valved cannula hub.

Abstract: A platform configured to secure a service loop of tubing from a fixed position surgical device. The platform allows for avoidance of taping and re-taping of service loops. Additionally, the platform provides stability to the surgical device so as to avoid unintentional changing of position or orientation of the device. This is of particular benefit for an infusion port during eye surgery and other similar devices where orientation of the installed device aids device performance.

Abstract: Embodiments disclosed herein provide devices, systems, and methods for instrument exchanges during ophthalmic surgery. More particularly, the present disclosure relates to valved cannula assemblies and methods of use thereof. A valved cannula assembly includes a cannula having a head at a proximal end of the cannula and a hollow rod extending from the head to a distal end of the cannula. The valved cannula assembly includes a valved hub coupled to the head and including a septum having two or more curved flaps configured to provide an opening for an instrument.

Abstract: Certain aspects of the present disclosure generally relate to ophthalmic surgery, and more particularly, to methods and apparatuses for controlling intraocular pressure (IOP) and administering ocular tamponades during or after ophthalmic surgery. An exemplary apparatus generally includes a proximal segment having a first inner diameter (ID), a first proximal end, and a first distal end. The apparatus further includes a distal segment having a second ID smaller than the first ID, a second proximal end, and a second distal end configured to be disposed inside a hub or a cannula transition of a valved cannula comprising the hub, a shaft, and the cannula transition between the hub and the shaft.

Abstract: Embodiments disclosed herein relate to an infusion cannula for infusion/venting of fluids to/from the eye to control intraocular pressure. The infusion cannula includes a tubular body with a tubular inlet located at a proximal end of the tubular body and a tubular outlet located at a distal end of the tubular body. The tubular outlet is aligned with a first longitudinal axis and configured to extend through a septum of a valved cannula hub. The infusion cannula includes a retention piece extending from or coupled to the tubular body. The retention piece has an annular body surrounding the tubular body at the distal end of the tubular body and configured to be coupled to the valved cannula hub. An inner surface of the annular body has a profile configured to form a snap fit with an overhang formed along an outer surface of the valved cannula hub.

Abstract: The present disclosure relates to trocar-cannula insertion tools for ophthalmic procedures. In certain embodiments, a cap for a trocar-cannula insertion tool includes a body having a proximal end and a distal end opposite the proximal end. A marking element extends in a distal direction from the distal end of the body and includes at least one marking tip for forming one or more indentations on a patient's eye during an ophthalmic procedure. A manipulation element extends from the body in a direction different from the marking element and includes at least one manipulation tip for gripping a tissue of the patient's eye during the ophthalmic procedure. In certain embodiments, the cap further includes at least one window for exposing a photoluminescent cannula of the trocar-cannula insertion tool to light, enabling the cannula to absorb photons prior to insertion thereof.

Abstract: A method and system for disinfecting or sanitizing with aqueous ozone sprayed at high pressures. The method includes producing aqueous ozone having an ozone concentration of about 1 ppm to about 4 ppm. The method includes, delivering the aqueous ozone to a sprayer at a pressure of about 200 psi to about 600 psi. The method includes spraying the pressurized aqueous ozone at a surface to reduce microbe populations on the surface.

Abstract: A cooling system for a microchip or other component is described, including, in one embodiment: (1) a cold plate assembly positioned adjacent (e.g., in contact with) the component to be cooled; (2) at least one heat exchanger; (3) a fan for directing gas adjacent (e.g., through) a portion of the heat exchanger; and (4) a pump for circulating cooling fluid through a closed circuit including the cold plate and heat exchanger. The cold plate may include guide fins that define macrochannels and microchannels that serve as conduits for the cooling fluid. The fins and channels in one embodiment are shaped to substantially match the heat map profile of the chip or component to be cooled. The heat exchanger in one embodiment includes a reservoir in its base which may cooperate with a recess or channel in a support plate to form an additional cooling fluid flow passage.