Patents by Inventor Ashley Barry

Ashley Barry has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions comprising an internalizing nucleic acid molecule, and their methods of use
    Patent number: 10059950
    Abstract: Provided are internalizing nucleic acid molecules (“iNA”) that can bind and internalize into target cells containing a cell surface molecule to which the iNA can bind; an iNA further modified to include at least one chemical modification, wherein the at least one modification is selected from the group consisting of a chemical substitution in the nucleic acid sequence of the iNA, incorporation of a modified nucleotide into the iNA, conjugation to a linker, and conjugation to at least one effector moiety comprising one or more of a drug or a detectable moiety or a combination thereof; and methods of using modified iNA to deliver at least one effector moiety into the target cells.
    Type: Grant
    Filed: April 17, 2013
    Date of Patent: August 28, 2018
    Assignee: Upstream Technologies, Inc.
    Inventors: Doug Ahrens, Ashley Barry, Michael Greenberg
  • Compositions comprising an internalizing nucleic acid molecule, and their methods of use
    Publication number: 20170240895
    Abstract: Provided are internalizing nucleic acid molecules (“iNA”) that can bind and internalize into target cells containing a cell surface molecule to which the iNA can bind; an iNA further modified to include at least one chemical modification, wherein the at least one modification is selected from the group consisting of a chemical substitution in the nucleic acid sequence of the iNA, incorporation of a modified nucleotide into the iNA, conjugation to a linker, and conjugation to at least one effector moiety comprising one or more of a drug or a detectable moiety or a combination thereof; and methods of using modified iNA to deliver at least one effector moiety into the target cells.
    Type: Application
    Filed: April 17, 2013
    Publication date: August 24, 2017
    Inventors: Doug Ahrens, Ashley Barry, Michael Greenberg