Patents by Inventor Ashley Jarvis

Ashley Jarvis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MAP4K4 inhibitors
    Patent number: 11795169
    Abstract: This invention relates to pyrrolopyrimidine comprising compounds that may be useful as inhibitors of Mitogen-activated Protein Kinase Kinase Kinase Kinase-4 (MAP4K4). The invention also relates to the use of these pyrrolopyrimidine comprising compounds, for example in a method of treatment. There are also provided processes for producing compounds of the present invention and method of their use. In particular, the present invention relates to compounds of formula (I).
    Type: Grant
    Filed: October 12, 2018
    Date of Patent: October 24, 2023
    Assignee: IMPERIAL COLLEGE INNOVATIONS LIMITED
    Inventors: Michael Schneider, Gary Newton, Katie Chapman, Trevor Perrior, Ashley Jarvis, Caroline Low, Rehan Aqil, Martin Fisher, Melanie Bayford, Nicholas Chapman, Nicholas Martin, Tifelle Reisinger, Gabriel Negoita-Giras, Lorna R. Fieldler
  • MAP4K4 INHIBITORS
    Publication number: 20230055250
    Abstract: This invention relates to compounds that may be useful as inhibitors of Mitogen-activated Protein Kinase Kinase Kinase Kinase-4 (MAP4K4). The invention also relates to the use these compounds, for example in a method of treatment of cardiac conditions.
    Type: Application
    Filed: December 4, 2019
    Publication date: February 23, 2023
    Inventors: Michael SCHNEIDER, Gary NEWTON, Kathryn CHAPMAN, Ashley JARVIS, Rehan ACIL, Tifelle REISINGER, Melanie BAYFORD, Nicholas CHAPMAN, Nicholas MARTIN
  • MrgprX2 Antagonists for the Treatment of Inflammatory Disorders
    Publication number: 20230029266
    Abstract: The present disclosure is directed to use of MrgprX2 antagonists in the treatment of inflammatory disorders, e.g., inflammatory disorders of the skin. This invention is also directed to pharmaceutical compositions comprising a MrgprX2 antagonist and a pharmaceutically or orally acceptable carrier for administration.
    Type: Application
    Filed: November 5, 2020
    Publication date: January 26, 2023
    Inventors: Ferda Cevikbas, Ashley Jarvis, Laura Gleave, Nina Connelly Ursinyova, Ricky Cain, Wei Tsung Yau
  • DEUTERATED COMPOUNDS AND IMAGING AGENTS FOR IMAGING HUNTINGTIN PROTEIN
    Publication number: 20220372045
    Abstract: Provided herein are certain compounds and imaging agents useful for detecting a disease or condition associated with protein aggregation, compositions thereof, and methods of their use.
    Type: Application
    Filed: April 26, 2022
    Publication date: November 24, 2022
    Inventors: Longbin Liu, Celia Dominguez, Jonathan Bard, Vinod Khetarpal, Ashley Jarvis, Sarah Hayes, John E. Mangette
  • MAP4K4 INHIBITORS
    Publication number: 20200339583
    Abstract: This invention relates to pyrrolopyrimidine comprising compounds that may be useful as inhibitors of Mitogen-activated Protein Kinase Kinase Kinase Kinase-4 (MAP4K4). The invention also relates to the use of these pyrrolopyrimidine comprising compounds, for example in a method of treatment. There are also provided processes for producing compounds of the present invention and method of their use. In particular, the present invention relates to compounds of formula (I).
    Type: Application
    Filed: October 12, 2018
    Publication date: October 29, 2020
    Inventors: Michael SCHNEIDER, Gary NEWTON, Katie CHAPMAN, Trevor PERRIOR, Ashley JARVIS, Caroline LOW, Rehan AQIL, Martin FISHER, Melanie BAYFORD, Nicholas CHAPMAN, Nicholas MARTIN, Tifelle REISINGER, Gabriel NEGOITA-GIRAS, Lorna R. FIELDLER
  • Arginine Derivatives with NP-I Antagonistic Activity
    Publication number: 20120269864
    Abstract: The present invention is a compound of formula (I) or formula (II) which are suitable as NP-1 antagonists.
    Type: Application
    Filed: June 11, 2012
    Publication date: October 25, 2012
    Inventors: Haiyan Jia, Ian ZACHARY, Michelle TICKNER, Lili CHENG, Chris CHAPMAN, Katie ELLARD, Basil HARTZOULAKIS, Ashley JARVIS, Rosemary LYNCH, Jamie NALLY, David SELWOOD, Mark STEWART
  • Arginine derivatives with NP-1 antagonistic activity
    Patent number: 8227606
    Abstract: The present invention is a compound of formula (I) or formula (II) which are suitable as NP-1 antagonists.
    Type: Grant
    Filed: January 30, 2012
    Date of Patent: July 24, 2012
    Assignee: Ark Therapeutics, Ltd.
    Inventors: Haiyan Jia, Ian Zachary, Michelle Tickner, Lili Cheng, Chris Chapman, Katie Ellard, Basil Hartzoulakis, Ashley Jarvis, Rosemary Lynch, Jamie Nally, David Selwood, Mark Stewart
  • ARGININE DERIVATIVES WITH NP-I ANTAGONISTIC ACTIVITY
    Publication number: 20120122862
    Abstract: The present invention is a compound of formula (I) or formula (II) which are suitable as NP-1 antagonists.
    Type: Application
    Filed: January 30, 2012
    Publication date: May 17, 2012
    Inventors: Haiyan Jia, Ian Zachary, Michelle Tickner, Lili Cheng, Chris Chapman, Katie Ellard, Basil Hartzoulakis, Ashley Jarvis, Rosemary Lynch, Jamie Nally, David Selwood, Mark Stewart
  • Arginine derivatives with NP-I antagonistic activity
    Patent number: 8158789
    Abstract: The present invention is a compound of formula (I) or formula (II) which are suitable as NP-1 antagonists.
    Type: Grant
    Filed: October 4, 2007
    Date of Patent: April 17, 2012
    Assignee: Ark Therapeutics Group Ltd.
    Inventors: Haiyan Jia, Ian Zachary, Michelle Tickner, Lili Cheng, Chris Chapman, Katie Ellard, Basil Hartzoulakis, Ashley Jarvis, Rosemary Lynch, Jamie Nally, David Selwood, Mark Stewart
  • Arginine Derivatives with NP-I Antagonistic Activity
    Publication number: 20100022525
    Abstract: The present invention is a compound of formula (I) or formula (II) which are suitable as NP-1 antagonists.
    Type: Application
    Filed: October 4, 2007
    Publication date: January 28, 2010
    Inventors: Haiyan Jia, Ian Zachary, Michelle Tickner, Lili Cheng, Chris Chapman, Katie Ellard, Basil Hartzoulakis, Ashley Jarvis, Rosemary Lynch, Jamie Nally, David Selwood, Mark Stewart