Patents by Inventor Ashley Mahne

Ashley Mahne has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230104151
    Abstract: This document relates to methods and materials for treating a mammal having an autoimmune disease. For example, materials and methods for producing a T cell comprising a FOXP3 polypeptide and one or more transcription factors are provided herein. Methods and materials for treating a mammal having an autoimmune disease comprising administering to a mammal having an autoimmune disease an effective amount of a T cell are also provided herein.
    Type: Application
    Filed: November 2, 2022
    Publication date: April 6, 2023
    Applicant: Kyverna Therapeutics, Inc.
    Inventors: Ashley Mahne, John Lee, Lih-Yun Hsu, Jeffrey Greve
  • Patent number: 11446357
    Abstract: This document relates to methods and materials for treating a mammal having an autoimmune disease. For example, materials and methods for producing a T cell comprising a FOXP3 polypeptide and one or more transcription factors are provided herein. Methods and materials for treating a mammal having an autoimmune disease comprising administering to a mammal having an autoimmune disease an effective amount of a T cell are also provided herein.
    Type: Grant
    Filed: December 16, 2021
    Date of Patent: September 20, 2022
    Assignee: Kyverna Therapeutics, Inc.
    Inventors: Ashley Mahne, John Lee, Lih-Yun Hsu, Jeffrey Greve
  • Publication number: 20220169687
    Abstract: This document relates to methods and materials for treating a mammal having an autoimmune disease. For example, materials and methods for producing a T cell comprising a FOXP3 polypeptide and one or more transcription factors are provided herein. Methods and materials for treating a mammal having an autoimmune disease comprising administering to a mammal having an autoimmune disease an effective amount of a T cell are also provided herein.
    Type: Application
    Filed: November 10, 2021
    Publication date: June 2, 2022
    Inventors: Ashley Mahne, John Lee, Lih-Yun Hsu, Jeffrey Greve
  • Publication number: 20220143134
    Abstract: This document relates to methods and materials for treating a mammal having an autoimmune disease. For example, materials and methods for producing a T cell comprising a FOXP3 polypeptide and one or more transcription factors are provided herein. Methods and materials for treating a mammal having an autoimmune disease comprising administering to a mammal having an autoimmune disease an effective amount of a T cell are also provided herein.
    Type: Application
    Filed: December 16, 2021
    Publication date: May 12, 2022
    Inventors: Ashley Mahne, John Lee, Lyn Hsu, Jeffrey Greve
  • Publication number: 20220110975
    Abstract: This document relates to methods and materials for treating a mammal having an autoimmune disease. For example, materials and methods for producing a T cell comprising a FOXP3 polypeptide and a microRNA are provided herein. Also provided are methods of treating an autoimmune disease that include administering these T cells.
    Type: Application
    Filed: October 12, 2021
    Publication date: April 14, 2022
    Inventors: Sarah Levinson, John Lee, Jordan Tsai, Jeanne Flandez, Ashley Mahne, Faye Wu, Sasha Farina, Harsh Srivastava, Joseph Park, Jeffrey Greve, Fred Cohen