Patents by Inventor Ashok Badithe

Ashok Badithe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for producing antigen-binding proteins against foreign antigens
    Patent number: 12342801
    Abstract: Methods and compositions are provided for generating antigen-binding proteins against a foreign antigen of interest.
    Type: Grant
    Filed: December 16, 2021
    Date of Patent: July 1, 2025
    Assignee: Regeneron Pharmaceuticals, Inc.
    Inventors: Vera Voronina, Lynn Macdonald, Marine Prissette, Ka-Man Venus Lai, Ashok Badithe, Andrew J. Murphy, Gustavo Droguett, David Frendewey, Brian Zambrowicz
  • METHODS FOR PRODUCING ANTIGEN-BINDING PROTEINS AGAINST FOREIGN ANTIGENS
    Publication number: 20220167600
    Abstract: Methods and compositions are provided for generating antigen-binding proteins against a foreign antigen of interest.
    Type: Application
    Filed: December 16, 2021
    Publication date: June 2, 2022
    Applicant: Regeneron Pharmaceuticals, Inc.
    Inventors: Vera Voronina, Lynn Macdonald, Marine Prissette, Ka-Man Venus Lai, Ashok Badithe, Andrew J. Murphy, Gustavo Droguett, David Frendewey, Brian Zambrowicz
  • METHODS FOR BREAKING IMMUNOLOGICAL TOLERANCE USING MULTIPLE GUIDE RNAS
    Publication number: 20170332610
    Abstract: Methods and compositions are provided for making non-human animals with reduced tolerance of a foreign antigen of interest and making antigen-binding proteins against that foreign antigen of interest using such animals. The methods and compositions employ CRISPR/Cas9 systems using multiple guide RNAs to reduce or eliminate expression of a self-antigen homologous to or sharing an epitope of interest with the foreign antigen of interest or to reduce or eliminate expression of an epitope on the self-antigen that is shared with the foreign antigen of interest.
    Type: Application
    Filed: May 19, 2017
    Publication date: November 23, 2017
    Inventors: Vera Voronina, Lynn Macdonald, Marine Prissette, Ka-Man Venus Lai, Ashok Badithe, Andrew J. Murphy, Gustavo Droguett, David Frendewey, Brian Zambrowicz