Patents by Inventor Ashok Bajji

Ashok Bajji has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11629143
    Abstract: Provided herein are protein kinase inhibitors, which, in one aspect are selective inhibitors of HipK4. Pharmaceutical compositions and medical uses for the disclosed inhibitors are also provided.
    Type: Grant
    Filed: September 30, 2021
    Date of Patent: April 18, 2023
    Assignee: VIBLIOME THERAPEUTICS, LLC
    Inventors: Gary A. Flynn, Ashok Bajji, Khoi Huynh
  • Patent number: 11603372
    Abstract: The invention relates to compounds, pharmaceutical compositions and methods useful for treating cancer, systemic or chronic inflammation, rheumatoid arthritis, diabetes, obesity, T-cell mediated autoimmune disease, diseases associated with over production of IL12/IL23, lysosomal storage disorders, filovirus infections, ischemia, and other complications associated with these diseases and disorders.
    Type: Grant
    Filed: June 5, 2020
    Date of Patent: March 14, 2023
    Assignee: VioGen Biosciences, LLC
    Inventor: Ashok Bajji
  • Patent number: 11414442
    Abstract: Methods of treating vascular leak, vascular inflammation, angiogenesis, ocular disorders, and/or inflammatory disorders in a patient are provided. The methods can include administering an ADP-ribosylation factor 6 (ARF6) inhibitor to the patient. The present disclosure also relates to new chemical entities and pharmaceutical compositions including ARF6 inhibitors. The ARF6 inhibitor may be a prodrug of an ARF6 inhibitor.
    Type: Grant
    Filed: February 21, 2020
    Date of Patent: August 16, 2022
    Assignee: Navigen, Inc.
    Inventors: Ashok Bajji, Kirill Ostanin, Alan Mueller, Damon Papac
  • Publication number: 20220168315
    Abstract: The invention relates to compounds, pharmaceutical compositions and methods useful for treating cancer, systemic or chronic inflammation, rheumatoid arthritis, diabetes, obesity, T-cell mediated autoimmune disease, diseases associated with over production of IL12/IL23, lysosomal storage disorders, filovirus infections, ischemia, neurodegenerative diseases including Alzheimer's disease, amyotrophic lateral sclerosis, and frontotemporal dementia, viral infection including SARS-CoV-2, and other complications associated with the foregoing diseases and disorders.
    Type: Application
    Filed: November 29, 2021
    Publication date: June 2, 2022
    Inventor: Ashok Bajji
  • Publication number: 20220106303
    Abstract: Provided herein are protein kinase inhibitors, which, in one aspect are selective inhibitors of HipK4. Pharmaceutical compositions and medical uses for the disclosed inhibitors are also provided.
    Type: Application
    Filed: September 30, 2021
    Publication date: April 7, 2022
    Inventors: Gary A. Flynn, Ashok Bajji, Khoi Huynh
  • Publication number: 20210122752
    Abstract: The invention relates to compounds, pharmaceutical compositions and methods useful for treating cancer, systemic or chronic inflammation, rheumatoid arthritis, diabetes, obesity, T-cell mediated autoimmune disease, diseases associated with over production of IL12/IL23, lysosomal storage disorders, filovirus infections, ischemia, and other complications associated with these diseases and disorders.
    Type: Application
    Filed: June 5, 2020
    Publication date: April 29, 2021
    Inventor: Ashok Bajji
  • Publication number: 20210017201
    Abstract: Methods of treating vascular leak, vascular inflammation, angiogenesis, ocular disorders, and/or inflammatory disorders in a patient are provided. The methods can include administering an ADP-ribosylation factor 6 (ARF6) inhibitor to the patient. The present disclosure also relates to new chemical entities and pharmaceutical compositions including ARF6 inhibitors. The ARF6 inhibitor may be a prodrug of an ARF6 inhibitor.
    Type: Application
    Filed: February 21, 2020
    Publication date: January 21, 2021
    Inventors: Ashok Bajji, Kirill Ostanin, Alan Mueller, Damon Papac
  • Patent number: 10849901
    Abstract: Disclosed herein are compounds and methods for inhibiting Arf6. Pharmaceutical compositions and methods for treating a subject with an inhibitor of Arf6 are also disclosed herein.
    Type: Grant
    Filed: May 27, 2015
    Date of Patent: December 1, 2020
    Assignees: Navigen, Inc., The University of Utah Research Foundation
    Inventors: Kirill Ostanin, Mark Shenderovich, Ashok Bajji, Christopher L. Cioffi, Neil Moss, Hariprasad Vankayalapati, Dean Li
  • Publication number: 20170189405
    Abstract: Disclosed herein are compounds and methods for inhibiting Arf6. Pharmaceutical compositions and methods for treating a subject with an inhibitor of Arf6 are also disclosed herein.
    Type: Application
    Filed: May 27, 2015
    Publication date: July 6, 2017
    Applicants: Navigen, Inc., The University of Utah Research Foundation
    Inventors: Kirill Ostanin, Mark Shenderovich, Ashok Bajji, Christopher L. Cioffi, Neil Moss, Hariprasad Vankayalapati, Dean Li
  • Publication number: 20130053406
    Abstract: The invention provides novel therapeutic compounds, pharmaceutical compositions comprising these compounds, and methods for using these compounds and compositions to treat diseases and disorders such as cancer.
    Type: Application
    Filed: August 23, 2010
    Publication date: February 28, 2013
    Applicant: Myrexis, Inc.
    Inventors: SE-HO KIM, Herbert L. Ley, III, Ashok Bajji
  • Patent number: 8017780
    Abstract: The invention provides novel therapeutic compounds, pharmaceutical compositions comprising these compounds, and methods for using these compounds and compositions to treat diseases and disorders such as cancer.
    Type: Grant
    Filed: October 9, 2009
    Date of Patent: September 13, 2011
    Assignee: Myrexis, Inc.
    Inventors: Ashok Bajji, Se-Ho Kim, Rajendra Tangallapally
  • Publication number: 20070299258
    Abstract: The invention relates to compounds of Formulae I-III and their therapeutic uses.
    Type: Application
    Filed: May 14, 2007
    Publication date: December 27, 2007
    Applicant: Myriad Genetics, Incorporated
    Inventors: Ashok Bajji, Se-Ho Kim, Benjamin Markovitz, Richard Trovato, Rajendra Tangallapally, Mark Anderson, Daniel Wettstein, Mark Shenderovich, John Vanecko
  • Publication number: 20060148793
    Abstract: Novel ?-aryl-?-oxysubstituted alkylcarboxylic acids of the formula (I) and compositions containing them. The compounds have hypolipidemic, antihyperglycemic uses.
    Type: Application
    Filed: July 14, 2005
    Publication date: July 6, 2006
    Inventors: Braj Lohray, Vidya Lohray, Ashok Bajji, Shivaramayya Kalchar, Rajagopalan Ramanujam, Ranjan Chakrabarti
  • Publication number: 20050187300
    Abstract: Compounds and pharmaceutical compositions containing the same are provided, which are useful in therapeutic treatment or prevention of various diseases.
    Type: Application
    Filed: January 18, 2005
    Publication date: August 25, 2005
    Applicant: Myriad Genetics, Incorporated
    Inventors: Ashok Bajji, Esther Arranz, Jayasree Srinlvasan, Eric Delmar, Rachel Slade, Jon Willardsen