Abstract: Use of modified metal oxides for the purification and enrichment of negatively charged biomolecules such as peptides, proteins, DNA, RNA, Lipids, carbohydrates, glyco molecules. These metal oxides are modified in such a way that the density of the Lewis acid group is reduced due to modification.

Abstract: A pipette tip or tube containing chromatographic media contained and held in place in said tube by using low melting point porous polymer particles. Such pipette tips or tubes can be used for sample preparation, filtration and synthesis of small molecules and biomolecules.

Abstract: This invention relates to a pipette tip or tube designed to perform biological or chemical sample preparation, purification or separation. The narrow end of the pipette tip is twisted in such a way that it forms a narrow spiral passage, which allows the retention of the chromatographic material in the pipette tip. The narrow spiral formed by twisting the capillary or the tube creates an opening that is large enough to permit the passage of fluids or smaller particles, but small enough to block the passage of solid materials or larger particles, The device described herein can be used for sample separation or purification using a vacuum, pressure, centrifugation, gravitation or other separation methods.

Abstract: The present invention is a mask coated with water absorbing material for preventing or reducing the transmission of infections such as flu, viral and bacterial pathogens which can be transmitted from human to human or animal to human or human to animal through saliva, nasal fluid or inhalation.

Abstract: The present invention provides a method for manufacture of a grid structure for use in lead acid batteries using a substrate having low density and low melting point, the method comprising coating the substrate material with a first metal layer and a subsequent metal layer of lead/lead alloy and electrodepositing an electroconductive polymer to form a protective layer thereon.

Abstract: Use of modified metal oxides for the purification and enrichment of negatively charged biomolecules such as peptides, proteins, DNA, RNA, Lipids, carbohydrates, glyco molecules. These metal oxides are modified in such a way that the density of the Lewis acid group is reduced due to modification.

Abstract: The use of hydrophobic coated metal oxides particles or film for the purifications of proteins, peptides or other biomolecules. This process eliminates two steps of purification as compared to silica or polymer based particles.

Abstract: This invention relates to a pipette tip or tube designed to perform biological or chemical sample preparation, purification or separation. The narrow end of the pipette tip is twisted in such a way that it forms a narrow spiral passage, which allows the retention of the chromatographic material in the pipette tip. The narrow spiral formed by twisting the capillary or the tube creates an opening that is large enough to permit the passage of fluids or smaller particles, but small enough to block the passage of solid materials or larger particles, The device described herein can be used for sample separation or purification using a vacuum, pressure, centrifugation, gravitation or other separation methods.

Abstract: This invention relates to a pipette tip designed to perform filtration or sample separation on the basis of one or more perforations, holes or incisions performed on the tip. Such perforation, holes or incisions are large enough to permit the passage of fluids or smaller particles, but small enough to block the passage of solid materials or larger particles, such as those including chromatography media. Such a pipette tip can thus be used for the filtration or separation of samples without the use of a filter, secondary solid matrix or any other components needed to hold chromatography media and other solid matrices within the pipette tip during the separation process.

Abstract: This invention relates to a novel method for small sample preparation using a tube or column, such as a pipette tip, in which the interior surface is coated with a solid matrix for sample preparation. Said solid matrix is composed of a polymeric substance such as polytetrafluoroethylene (PTFE) and one or more column materials such as reactive or absorptive materials suited for sample filtration, separation or purification. The desired sample, containing bio-molecules such as DNA, proteins or other molecular components, is passed through said tube or column, which may be a pipette tip, or like structure.

Abstract: In the present invention we describe a new method for the formation of a mucin-biomolecules complex, such as a mucin-DNA (deoxyribonucleic acid) complex and the application of such a complex for the transport of DNA, RNA (ribonucleic acid) and other biomolecules into cells. Transfection is the introduction of a DNA molecule into a eukaryotic cell, usually followed by the expression of one or more genes in the newly introduced DNA. The mucin-DNA complex described in the present invention can be used to perform transfection of DNA, as well as, the introduction of RNA and other larger biomolecules into cells. Since effective transfection, especially in in vivo systems is still limited by the methods currently available, the mucin-DNA complex, as described in the present invention, presents a novel and significantly improved method for performing transfection and ensuring the effective transmission of DNA into cells and the expression of genes in transfected DNA.

Abstract: The present invention describes a reaction chamber consisting of a reactant-containing aqueous solution, which may be in droplet form, coated with a hydrophobic powder such as polytetrafluoroethylene, polypropylene, polyolefins, polyethylene or hydrocarbon-coated particles such as hydrocarbon-coated silica. The polymer particles are preferably less than 500 microns in size. Charcoal, metal powder or silica powder can be inserted inside or on the surface of the reaction chamber droplet. Also, a reaction chamber droplet containing a first reactant such as an enzyme-bound bead can be combined with a second reaction chamber droplet containing a second reactant to mix the reactants in the two chambers resulting in a subsequent reaction. A dialysis or filtration membrane can also be placed on a reaction chamber droplet for dialysis using the droplet chamber. Electrochemical reactions can be performed by placing the droplet chamber between two electrodes and producing current flow between them.

Abstract: This invention relates to micro volume spin columns used for the preparation and purification of small chemical and/or biological samples by centrifugation. The present invention relates to the use of the conventional luer lock fitting in micro volume spin columns. This invention also relates to multi-spin column systems based on joining two or more spin columns by their ends or by combining different filtration or ultra-filtration membranes with spin columns.

Abstract: A device and method for sensing fluid characteristics, including, temperature, pH and chemistry, comprises a switch affixed to or embedded in a container of a size, shape and density such that said container floats stable in said liquid sensors which measure and report other characteristics of the liquid, such as temperature, pH, viscosity, chemistry or biochemistry.

Abstract: This invention relates to a tilt switch, which when activated sends signals to a wireless remote receiver. The receiver will alert the human operator and/or execute a process or any programmed action.

Abstract: The present invention presents a novel method for both staining electrophoresis gels, as well as removing the background dye during de-staining. This novel and simple pad-based technique minimizes solvent consumption, is environmentally friendly, and does not leave any solid residues on the gel. Furthermore, a novel method for the quantitative and qualitative determination of protein concentration in solution is also presented. This method is simple, easy-to-use and has an easily visible color change from clear to blue in the presence of protein.

Abstract: A reaction chamber is constructed of a reactant-containing aqueous solution, which may be in droplet form, coated with a fluoropolymer powder such as Polytetrafluoroethylene (PTFE), preferably having a particle size of less than 500 microns. After a reaction, the droplet is destroyed by adding a substance such as a detergent or organic solvent, and the fluoropolymer powder is removed by centrifuging and filtering. Using a micropipette, size of the droplet chamber is increased or decreased by removing or adding liquid, or liquid is transferred from one droplet chamber to another. Charcoal, metal powder or silica powder can be inserted inside or on the surface of the droplet. A droplet chamber containing a first reactant such as an enzyme-bound bead is combined with a second droplet chamber containing a second reactant to react the first and second reactants. A dialysis chamber contains a filtration membrane in contact with the droplet chamber.

Abstract: A device and method for sensing fluid characteristics, including level, temperature, pH and chemistry, comprises a switch affixed to or embedded in a container of a size, shape and density such that said container floats stably in said liquid until a predetermined level is reached; the container tilts so as to operate the switch when the liquid drops below or increases above a predetermined level. The device may contain additional sensors which measure and report other characteristics of the liquid, such as temperature, pH, viscosity, chemistry or biochemistry.

Abstract: This invention relates to the use of the conventional necktie as a source of information or for communicating a message in text and/or graphic, either by printing, painting, embroidering, or by thermal, chemical, and physical bonding to the surface of the necktie.

Abstract: A microdialysis system for the dialysis of small sample volumes of protein, nucleic acid, peptide, and other biomolecules has been developed. The device may contain a built-in magnet to permit remote rotation of the device during dialysis. Double sided dialysis chambers can be used for electrodialysis, electroelution, or electroconcentration. Two or more chambers can be joined either by a union or directly for equilibrium dialysis, or other applications.