Patents by Inventor Ashok Kumar Nuvvula

Ashok Kumar Nuvvula has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20080171857
    Abstract: The present invention describes a novel process for large scale purification of therapeutic grade quality of recombinant human G-CSF from microbial cells, wherein the protein is expressed as inclusion bodies. The process involves the novel use of Hydrophobic Interaction Chromatography (HIC) step to purify G-CSF eluted from a cation exchange column. A combination of these two chromatography steps provides good purity and yields which are essential for a production scale process. The host cell related contaminants like proteins, DNA and endotoxins are estimated to be within the specifications outlined by the drug regulatory authorities.
    Type: Application
    Filed: March 13, 2006
    Publication date: July 17, 2008
    Inventors: Uma Devi Komath, Anupama Nandamuri, Ashok Kumar Nuvvula, Srilalitha Movva, Sreenivasu Karra, Mitali Samaddar, Jayaram Chigurupati