Patents by Inventor Ashraf AMANULLAH

Ashraf AMANULLAH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Formulations of DR5 Binding Polypeptides
    Publication number: 20250332098
    Abstract: Provided herein are formulations of DR5-binding polypeptides. Uses of the DR5-binding polypeptides are also provided.
    Type: Application
    Filed: February 18, 2022
    Publication date: October 30, 2025
    Applicant: Inhibrx Biosciences, Inc.
    Inventors: Ashraf Amanullah, Brian Lobo
  • AQUEOUS SOLUTION COMPOSITIONS FOR INCREASING STABILITY OF ENGINEERED DIMERIC PROTEINS
    Publication number: 20250177501
    Abstract: The present application relates to aqueous solution compositions of engineered dimeric proteins comprising monomers that comprise at least one human serpin polypeptide operably linked to a human immunoglobulin Fc polypeptide or a polypeptide that is derived from an immunoglobulin Fc polypeptide, at low buffer concentrations and low ionic strength and containing a neutral amino acid. The aqueous solution compositions increase the stability of the an Fc domain in aqueous solution compositions, and in particular increase the stability of an engineered dimeric protein.
    Type: Application
    Filed: September 30, 2024
    Publication date: June 5, 2025
    Inventors: Jan Jezek, David Gerring, Joshua Cremin, Jorge Pinto, Ashraf Amanullah, Brian Lobo, Bradley Hayes
  • AQUEOUS SOLUTION COMPOSITIONS FOR INCREASING STABILITY OF ENGINEERED DIMERIC PROTEINS
    Publication number: 20220265788
    Abstract: The present application relates to aqueous solution compositions of engineered dimeric proteins comprising monomers that comprise at least one human serpin polypeptide operably linked to a human immunoglobulin Fc polypeptide or a polypeptide that is derived from an immunoglobulin Fc polypeptide, at low buffer concentrations and low ionic strength and containing a neutral amino acid. The aqueous solution compositions increase the stability of the an Fc domain in aqueous solution compositions, and in particular increase the stability of an engineered dimeric protein.
    Type: Application
    Filed: February 17, 2022
    Publication date: August 25, 2022
    Inventors: Jan JEZEK, David GERRING, Joshua CREMIN, Jorge PINTO, Ashraf AMANULLAH, Brian LOBO, Bradley HAYES