Patents by Inventor Ashraf Imam

Ashraf Imam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibody to antigen specifically expressed on the surface of B cells and Hodgkin's cells
    Patent number: 5658743
    Abstract: The invention relates to a new antigen termed BLA-36 specifically expressed on the surface of Hodgkin's cells, Reed-Sternberg cells and B lymphocytes, and to a new monoclonal antibody (anti-BLA-36) specific thereto. The antigen is characterized by the following properties:a molecular weight of about 36,000 D;the presence of an epitope recognized by antibody to said protein;specific expression by Hodgkin's cells and Reed-Sternberg cells in all subsets of Hodgkin's disease, and by activated and early proliferating B cells;no expression by T cells;capability of reacting with its antibody in both frozen and fixed/paraffin embedded tissues;a function associated with the growth of cells capable to express said antigen protein.
    Type: Grant
    Filed: April 18, 1994
    Date of Patent: August 19, 1997
    Assignee: University of Southern California
    Inventors: Ashraf Imam, Clive R. Taylor
  • Antigen specifically expressed on the surface of B cells and Hodgkin's cells
    Patent number: 5304635
    Abstract: The invention relates to a new antigen termed BLA-35 specifically expressed on the surface of Hodgkin's cells, Reed-Sternberg cells and B lymphocytes, and to a new monoclonal antibody (anti-BLA-36) specific thereto. The antigen is characterized by the following properties:a molecular weight of about 36,000 D;the presence of an epitope recognized by antibody to said protein;specific expression by Hodgkin's cells and Reed-Sternberg cells in all subsets of Hodgkin's disease, and by activated and early proliferating B cells;no expression by T cells;capability of reacting with its antibody in both frozen and fixed/paraffin embedded tissues;a function associated with the growth of cells capable to express said antigen protein.
    Type: Grant
    Filed: December 16, 1992
    Date of Patent: April 19, 1994
    Assignee: University of Southern California
    Inventors: Ashraf Imam, Clive R. Taylor