Patents by Inventor Ashraf Imam

Ashraf Imam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240167923
    Abstract: A method of making a tissue reference control block is disclosed wherein cancer cells are selected with a known positivity or negativity for a specific marker and cancer cells are grown to a certain phase. The cancer cells are screened for an expression of the specific marker and the screened cancer cells are mixed with stromal cells and co-cultured in a bio-reactor bag. A spheroid grown from the co-cultured mixture of cells is harvested, fixed, and embedded in a core of a paraffin block.
    Type: Application
    Filed: July 7, 2023
    Publication date: May 23, 2024
    Applicant: SLMP, LLC
    Inventor: Syed Ashraf IMAM
  • Patent number: 11325185
    Abstract: A multi-step method to produce materials, and coatings of materials, which has three key characteristics. The first is that the density of the resulting materials or coatings can be controllably and widely variable from less than ten percent of normal density up to normal density. The second key characteristic of the invention is the use of starting materials having powders that have grains (particles) with one, two or three dimensions on the size scales of nanometers or micrometers. The third major characteristic part of the invention is the use of microwave radiation or induction heating to quickly raise the temperature of the powders to produce materials or coatings before deleterious diffusion and densification can occur. These features produce new types of materials with properties favorable to many applications, such as chemical and other catalysis, electrolysis in batteries and fuel cells, and light weight structural components.
    Type: Grant
    Filed: November 4, 2019
    Date of Patent: May 10, 2022
    Assignee: The George Washington University
    Inventors: David Joseph Nagel, M. Ashraf Imam
  • Publication number: 20200139438
    Abstract: A multi-step method to produce materials, and coatings of materials, which has three key characteristics. The first is that the density of the resulting materials or coatings can be controllably and widely variable from less than ten percent of normal density up to normal density. The second key characteristic of the invention is the use of starting materials having powders that have grains (particles) with one, two or three dimensions on the size scales of nanometers or micrometers. The third major characteristic part of the invention is the use of microwave radiation or induction heating to quickly raise the temperature of the powders to produce materials or coatings before deleterious diffusion and densification can occur. These features produce new types of materials with properties favorable to many applications, such as chemical and other catalysis, electrolysis in batteries and fuel cells, and light weight structural components.
    Type: Application
    Filed: November 4, 2019
    Publication date: May 7, 2020
    Inventors: David Joseph Nagel, M. Ashraf Imam
  • Patent number: 10329623
    Abstract: The disclosed embodiments include methods to form STC and STMC for use in determining presence of cancer, and methods to detect presence of cancer. In one embodiment, A portion of a STC is stained. The STC includes normal cells and cancer cells of a type of cancer co-cultured based on at least one cell culturing factors. The at least one co-culture factors includes a type of the cancer cells being cultured, a ratio of the cancer cells to the normal cells being co-cultured, seeding density of the normal cells and the cancer cells being co-cultured, a type of cell growth supplement used to facilitate culturing the cells, and a concentration of the cell growth supplement used to facilitate co-culturing the cells. The stained portion is observed to determine presence of one or more biomarker types that indicate presence of cancer.
    Type: Grant
    Filed: October 12, 2015
    Date of Patent: June 25, 2019
    Assignee: SLMP, LLC
    Inventors: Syed Ashraf Imam, Mark Lee Rees
  • Publication number: 20180275027
    Abstract: The disclosed embodiments include methods to improve yield of cultured cells of STC and STMC for use in determining presence of cancer, and methods to detect presence of cancer. In one embodiment, the method includes solidifying a fluidly gel to form a solid cell holder. The method also includes forming a cavity in the cell holder to hold co-cultured cells, the cell holder operable to hold a plurality of cell culture bags of co-cultured cells, the co-cultured cells comprising normal cells and cancer cells of a type of cancer. The method further includes depositing co-cultured cells from at least two of the plurality of cell culture bags of co-cultured cells in the cavity of the cell holder and processing the co-cultured cells to form the synthetic tissue control.
    Type: Application
    Filed: March 22, 2017
    Publication date: September 27, 2018
    Inventors: Syed Ashraf IMAM, Mark Lee REES
  • Publication number: 20170059456
    Abstract: The disclosed embodiments include methods to form STC and STMC for use in determining presence of cancer, and methods to detect presence of cancer. In one embodiment, A portion of a STC is stained. The STC includes normal cells and cancer cells of a type of cancer co-cultured based on at least one cell culturing factors. The at least one co-culture factors includes a type of the cancer cells being cultured, a ratio of the cancer cells to the normal cells being co-cultured, seeding density of the normal cells and the cancer cells being co-cultured, a type of cell growth supplement used to facilitate culturing the cells, and a concentration of the cell growth supplement used to facilitate co-culturing the cells. The stained portion is observed to determine presence of one or more biomarker types that indicate presence of cancer.
    Type: Application
    Filed: October 12, 2015
    Publication date: March 2, 2017
    Inventors: Syed Ashraf Imam, Mark Lee Rees
  • Patent number: 9120679
    Abstract: This disclosure concerns a method of making silicon carbide involving adding agricultural husk material to a container, creating a vacuum or an inert atmosphere inside the container, applying conventional heating or microwave heating, heating rapidly, and reacting the material and forming silicon carbide (SiC).
    Type: Grant
    Filed: June 9, 2014
    Date of Patent: September 1, 2015
    Assignee: The United States of America, as represented by the Secretary of the Navy
    Inventors: Syed B Qadri, Arne W Fliflet, M Ashraf Imam, Bhakta B Rath, Edward P Gorzkowski, III
  • Publication number: 20140287907
    Abstract: This disclosure concerns a method of making silicon carbide involving adding agricultural husk material to a container, creating a vacuum or an inert atmosphere inside the container, applying conventional heating or microwave heating, heating rapidly, and reacting the material and forming silicon carbide (SiC).
    Type: Application
    Filed: June 9, 2014
    Publication date: September 25, 2014
    Applicant: The Government of the United States of America, as represented by the Secretary of the Navy
    Inventors: Syed B. Qadri, Arne W. Fliflet, M. Ashraf Imam, Bhakta B. Rath, Edward P. Gorzkowski, III
  • Publication number: 20130272947
    Abstract: This disclosure concerns a method of making silicon carbide involving adding one from the group of rice husk material, sorghum, peanuts, maple leaves, and/or corn husk material to a container, creating a vacuum or an inert atmosphere inside the container, applying conventional heating or microwave heating, heating rapidly, and reacting the material and forming silicon carbide (SiC).
    Type: Application
    Filed: March 8, 2013
    Publication date: October 17, 2013
    Applicant: The Government of the United States of America, as represented by the Secretary of the Navy
    Inventors: Syed B. Qadri, Arne W. Fliflet, M. Ashraf Imam, Bhakta B. Rath, Edward P. Gorzkowski, III
  • Patent number: 8431071
    Abstract: A method of sintering by: placing a compacted metal powder inside a cylindrically-shaped susceptor and in an inert atmosphere or a vacuum, and applying microwave or millimeter-wave energy to the powder until the powder is sintered.
    Type: Grant
    Filed: August 27, 2010
    Date of Patent: April 30, 2013
    Assignee: The United States of America, as represented by the Secretary of the Navy
    Inventors: M Ashraf Imam, Arne W Fliflet
  • Publication number: 20120051962
    Abstract: A method of sintering by: placing a compacted metal powder inside a cylindrically-shaped susceptor and in an inert atmosphere or a vacuum, and applying microwave or millimeter-wave energy to the powder until the powder is sintered.
    Type: Application
    Filed: August 27, 2010
    Publication date: March 1, 2012
    Applicant: THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY
    Inventors: M. Ashraf Imam, Arne W. Fliflet
  • Patent number: 7824576
    Abstract: A composite material includes lithium hydride particles dispersed within lithium to form a lithium-lithium hydride composite. The lithium-lithium hydride composite has increased strength over pure lithium and similar soft X-ray transmission characteristics as pure lithium. A soft X-ray blast window may be made from the lithium-lithium hydride composite with increased reliability and cost effectiveness. A method for making a composite material includes dispersing lithium hydride into lithium metal using a variety of dispersion techniques.
    Type: Grant
    Filed: March 23, 2010
    Date of Patent: November 2, 2010
    Assignee: The United States of America as represented by the Secretary of the Navy
    Inventors: Nino R Pereira, M Ashraf Imam
  • Publication number: 20100176348
    Abstract: A composite material includes lithium hydride particles dispersed within lithium to form a lithium-lithium hydride composite. The lithium-lithium hydride composite has increased strength over pure lithium and similar soft X-ray transmission characteristics as pure lithium. A soft X-ray blast window may be made from the lithium-lithium hydride composite with increased reliability and cost effectiveness. A method for making a composite material includes dispersing lithium hydride into lithium metal using a variety of dispersion techniques.
    Type: Application
    Filed: March 23, 2010
    Publication date: July 15, 2010
    Inventors: Nino R. Pereira, M. Ashraf Imam
  • Patent number: 7632565
    Abstract: Metal foams are impregnated with resins. The metal foam/polymer composite formed upon curing has excellent acoustic dampening and structural properties. Foams of various metals, such as aluminum, titanium, nickel, copper, iron, zinc, lead, silver, gold, platinum, tantalum, and alloys based on these metals, may be used. The polymer component may be any polymeric resin, for example, epoxy, natural rubber, acrylic, or phenolic.
    Type: Grant
    Filed: April 28, 1997
    Date of Patent: December 15, 2009
    Assignee: The United States of America as represented by the Secretary of the Navy
    Inventors: M. Ashraf Imam, Bhakta B. Rath, Teddy M. Keller
  • Patent number: 7381368
    Abstract: A palladium-boron composition and methods of making and using same are provided. In one aspect, the invention comprises an alloy comprising palladium and boron, the boron being in solid solution in the palladium and the alloy having a two-phase structure, wherein each phase of the two-phase structure has the same crystal structure as the other phase and has a different set of lattice parameters from the other phase such that the palladium is greatly hardened by the presence of the smaller phase crystals within the spaces between the larger phase crystals. The composition is carefully prepared by a process wherein palladium and an amount of boron sufficient to place the boron in solid solution, but insufficient to combine with the palladium, are placed together and repeatedly are melted, cooled and turned over until sufficiently mixed.
    Type: Grant
    Filed: August 23, 2004
    Date of Patent: June 3, 2008
    Assignee: The United States of America as represented by the Secretary of the Navy
    Inventors: Melvin H. Miles, M. Ashraf Imam
  • Publication number: 20080093585
    Abstract: A composite material includes lithium hydride particles dispersed within lithium to form a lithium-lithium hydride composite. The lithium-lithium hydride composite has increased strength over pure lithium and similar soft X-ray transmission characteristics as pure lithium. A soft X-ray blast window may be made from the lithium-lithium hydride composite with increased reliability and cost effectiveness. A method for making a composite material includes dispersing lithium hydride into lithium metal using a variety of dispersion techniques.
    Type: Application
    Filed: October 23, 2006
    Publication date: April 24, 2008
    Inventors: Nino R. Pereira, M. Ashraf Imam
  • Patent number: 7279292
    Abstract: A method for identifying low grade astrocytoma cells in a sample is provided, wherein the method distinguishes between low grade astrocytoma cells and normal astrocytes, thus permitting early diagnosis of astrocytoma. The method uses antibody directed against J1-31 to test astrocytes in the sample for the presence or absence of J1-31 polypeptide, the low grade astrocytoma cells being characterized by the absence of J1-31 while normal astrocytes are characterized by the presence of J1-31.
    Type: Grant
    Filed: August 17, 2006
    Date of Patent: October 9, 2007
    Assignees: Governors of the University of Alberta, Huntington Medical Research Institutes
    Inventors: S. Ashraf Imam, Sudarshan Malhotra
  • Patent number: 6764561
    Abstract: A palladium-boron composition and methods of making and using same are provided. In one aspect, the invention comprises an alloy comprising palladium and boron, the boron being in solid solution in the palladium and the alloy having a two-phase structure, wherein each phase of the two-phase structure has the same crystal structure as the other phase and has a different set of lattice parameters from the other phase such that the palladium is greatly hardened by the presence of the smaller phase crystals within the spaces between the larger phase crystals. The composition is carefully prepared by a process wherein palladium and an amount of boron sufficient to place the boron in solid solution, but insufficient to combine with the palladium, are placed together and repeatedly arc melted, cooled and turned over until sufficiently mixed.
    Type: Grant
    Filed: August 30, 2000
    Date of Patent: July 20, 2004
    Assignee: The United States of America as represented by the Secretary of the Navy
    Inventors: Melvin H. Miles, M. Ashraf Imam
  • Patent number: 6700067
    Abstract: A high temperature superconducting composite rod, wire or tape is formed by filling the open cells of a reticulated foam structure made of silver, silver alloy, gold or gold alloy with a superconducting ceramic oxide or precursor, compacting the filled structure and forming it into a rod, wire or tape and heating it to melt and/or texture the superconducting ceramic oxide. The resulting composite has continuous ligaments of metal throughout a continuous region of superconducting ceramic oxide.
    Type: Grant
    Filed: July 10, 2000
    Date of Patent: March 2, 2004
    Assignee: The Secretary of the United States of America as represented by the Secretary of the Navy
    Inventors: Donald U. Gubser, M. Ashraf Imam
  • Publication number: 20030073146
    Abstract: A method for identifying low grade astrocytoma cells in a sample is provided, wherein the method distinguishes between low grade astrocytoma cells and normal astrocytes, thus permitting early diagnosis of astrocytoma. The method uses antibody directed against JI-31 to test astrocytes in the sample for the presence or absence of JI-31 polypeptide, the low grade astrocytoma cells being characterized by the absence of JI-31 while normal astrocytes are characterized by the presence of JI-31.
    Type: Application
    Filed: October 10, 2002
    Publication date: April 17, 2003
    Inventors: S. Ashraf Imam, Sudarshan Malhotra