Patents by Inventor Ashraf Imam
Ashraf Imam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240167923Abstract: A method of making a tissue reference control block is disclosed wherein cancer cells are selected with a known positivity or negativity for a specific marker and cancer cells are grown to a certain phase. The cancer cells are screened for an expression of the specific marker and the screened cancer cells are mixed with stromal cells and co-cultured in a bio-reactor bag. A spheroid grown from the co-cultured mixture of cells is harvested, fixed, and embedded in a core of a paraffin block.Type: ApplicationFiled: July 7, 2023Publication date: May 23, 2024Applicant: SLMP, LLCInventor: Syed Ashraf IMAM
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Patent number: 11325185Abstract: A multi-step method to produce materials, and coatings of materials, which has three key characteristics. The first is that the density of the resulting materials or coatings can be controllably and widely variable from less than ten percent of normal density up to normal density. The second key characteristic of the invention is the use of starting materials having powders that have grains (particles) with one, two or three dimensions on the size scales of nanometers or micrometers. The third major characteristic part of the invention is the use of microwave radiation or induction heating to quickly raise the temperature of the powders to produce materials or coatings before deleterious diffusion and densification can occur. These features produce new types of materials with properties favorable to many applications, such as chemical and other catalysis, electrolysis in batteries and fuel cells, and light weight structural components.Type: GrantFiled: November 4, 2019Date of Patent: May 10, 2022Assignee: The George Washington UniversityInventors: David Joseph Nagel, M. Ashraf Imam
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Publication number: 20200139438Abstract: A multi-step method to produce materials, and coatings of materials, which has three key characteristics. The first is that the density of the resulting materials or coatings can be controllably and widely variable from less than ten percent of normal density up to normal density. The second key characteristic of the invention is the use of starting materials having powders that have grains (particles) with one, two or three dimensions on the size scales of nanometers or micrometers. The third major characteristic part of the invention is the use of microwave radiation or induction heating to quickly raise the temperature of the powders to produce materials or coatings before deleterious diffusion and densification can occur. These features produce new types of materials with properties favorable to many applications, such as chemical and other catalysis, electrolysis in batteries and fuel cells, and light weight structural components.Type: ApplicationFiled: November 4, 2019Publication date: May 7, 2020Inventors: David Joseph Nagel, M. Ashraf Imam
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Patent number: 10329623Abstract: The disclosed embodiments include methods to form STC and STMC for use in determining presence of cancer, and methods to detect presence of cancer. In one embodiment, A portion of a STC is stained. The STC includes normal cells and cancer cells of a type of cancer co-cultured based on at least one cell culturing factors. The at least one co-culture factors includes a type of the cancer cells being cultured, a ratio of the cancer cells to the normal cells being co-cultured, seeding density of the normal cells and the cancer cells being co-cultured, a type of cell growth supplement used to facilitate culturing the cells, and a concentration of the cell growth supplement used to facilitate co-culturing the cells. The stained portion is observed to determine presence of one or more biomarker types that indicate presence of cancer.Type: GrantFiled: October 12, 2015Date of Patent: June 25, 2019Assignee: SLMP, LLCInventors: Syed Ashraf Imam, Mark Lee Rees
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Publication number: 20180275027Abstract: The disclosed embodiments include methods to improve yield of cultured cells of STC and STMC for use in determining presence of cancer, and methods to detect presence of cancer. In one embodiment, the method includes solidifying a fluidly gel to form a solid cell holder. The method also includes forming a cavity in the cell holder to hold co-cultured cells, the cell holder operable to hold a plurality of cell culture bags of co-cultured cells, the co-cultured cells comprising normal cells and cancer cells of a type of cancer. The method further includes depositing co-cultured cells from at least two of the plurality of cell culture bags of co-cultured cells in the cavity of the cell holder and processing the co-cultured cells to form the synthetic tissue control.Type: ApplicationFiled: March 22, 2017Publication date: September 27, 2018Inventors: Syed Ashraf IMAM, Mark Lee REES
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Publication number: 20170059456Abstract: The disclosed embodiments include methods to form STC and STMC for use in determining presence of cancer, and methods to detect presence of cancer. In one embodiment, A portion of a STC is stained. The STC includes normal cells and cancer cells of a type of cancer co-cultured based on at least one cell culturing factors. The at least one co-culture factors includes a type of the cancer cells being cultured, a ratio of the cancer cells to the normal cells being co-cultured, seeding density of the normal cells and the cancer cells being co-cultured, a type of cell growth supplement used to facilitate culturing the cells, and a concentration of the cell growth supplement used to facilitate co-culturing the cells. The stained portion is observed to determine presence of one or more biomarker types that indicate presence of cancer.Type: ApplicationFiled: October 12, 2015Publication date: March 2, 2017Inventors: Syed Ashraf Imam, Mark Lee Rees
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Patent number: 9120679Abstract: This disclosure concerns a method of making silicon carbide involving adding agricultural husk material to a container, creating a vacuum or an inert atmosphere inside the container, applying conventional heating or microwave heating, heating rapidly, and reacting the material and forming silicon carbide (SiC).Type: GrantFiled: June 9, 2014Date of Patent: September 1, 2015Assignee: The United States of America, as represented by the Secretary of the NavyInventors: Syed B Qadri, Arne W Fliflet, M Ashraf Imam, Bhakta B Rath, Edward P Gorzkowski, III
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Publication number: 20140287907Abstract: This disclosure concerns a method of making silicon carbide involving adding agricultural husk material to a container, creating a vacuum or an inert atmosphere inside the container, applying conventional heating or microwave heating, heating rapidly, and reacting the material and forming silicon carbide (SiC).Type: ApplicationFiled: June 9, 2014Publication date: September 25, 2014Applicant: The Government of the United States of America, as represented by the Secretary of the NavyInventors: Syed B. Qadri, Arne W. Fliflet, M. Ashraf Imam, Bhakta B. Rath, Edward P. Gorzkowski, III
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Publication number: 20130272947Abstract: This disclosure concerns a method of making silicon carbide involving adding one from the group of rice husk material, sorghum, peanuts, maple leaves, and/or corn husk material to a container, creating a vacuum or an inert atmosphere inside the container, applying conventional heating or microwave heating, heating rapidly, and reacting the material and forming silicon carbide (SiC).Type: ApplicationFiled: March 8, 2013Publication date: October 17, 2013Applicant: The Government of the United States of America, as represented by the Secretary of the NavyInventors: Syed B. Qadri, Arne W. Fliflet, M. Ashraf Imam, Bhakta B. Rath, Edward P. Gorzkowski, III
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Patent number: 8431071Abstract: A method of sintering by: placing a compacted metal powder inside a cylindrically-shaped susceptor and in an inert atmosphere or a vacuum, and applying microwave or millimeter-wave energy to the powder until the powder is sintered.Type: GrantFiled: August 27, 2010Date of Patent: April 30, 2013Assignee: The United States of America, as represented by the Secretary of the NavyInventors: M Ashraf Imam, Arne W Fliflet
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Publication number: 20120051962Abstract: A method of sintering by: placing a compacted metal powder inside a cylindrically-shaped susceptor and in an inert atmosphere or a vacuum, and applying microwave or millimeter-wave energy to the powder until the powder is sintered.Type: ApplicationFiled: August 27, 2010Publication date: March 1, 2012Applicant: THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVYInventors: M. Ashraf Imam, Arne W. Fliflet
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Patent number: 7824576Abstract: A composite material includes lithium hydride particles dispersed within lithium to form a lithium-lithium hydride composite. The lithium-lithium hydride composite has increased strength over pure lithium and similar soft X-ray transmission characteristics as pure lithium. A soft X-ray blast window may be made from the lithium-lithium hydride composite with increased reliability and cost effectiveness. A method for making a composite material includes dispersing lithium hydride into lithium metal using a variety of dispersion techniques.Type: GrantFiled: March 23, 2010Date of Patent: November 2, 2010Assignee: The United States of America as represented by the Secretary of the NavyInventors: Nino R Pereira, M Ashraf Imam
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Publication number: 20100176348Abstract: A composite material includes lithium hydride particles dispersed within lithium to form a lithium-lithium hydride composite. The lithium-lithium hydride composite has increased strength over pure lithium and similar soft X-ray transmission characteristics as pure lithium. A soft X-ray blast window may be made from the lithium-lithium hydride composite with increased reliability and cost effectiveness. A method for making a composite material includes dispersing lithium hydride into lithium metal using a variety of dispersion techniques.Type: ApplicationFiled: March 23, 2010Publication date: July 15, 2010Inventors: Nino R. Pereira, M. Ashraf Imam
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Patent number: 7632565Abstract: Metal foams are impregnated with resins. The metal foam/polymer composite formed upon curing has excellent acoustic dampening and structural properties. Foams of various metals, such as aluminum, titanium, nickel, copper, iron, zinc, lead, silver, gold, platinum, tantalum, and alloys based on these metals, may be used. The polymer component may be any polymeric resin, for example, epoxy, natural rubber, acrylic, or phenolic.Type: GrantFiled: April 28, 1997Date of Patent: December 15, 2009Assignee: The United States of America as represented by the Secretary of the NavyInventors: M. Ashraf Imam, Bhakta B. Rath, Teddy M. Keller
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Patent number: 7381368Abstract: A palladium-boron composition and methods of making and using same are provided. In one aspect, the invention comprises an alloy comprising palladium and boron, the boron being in solid solution in the palladium and the alloy having a two-phase structure, wherein each phase of the two-phase structure has the same crystal structure as the other phase and has a different set of lattice parameters from the other phase such that the palladium is greatly hardened by the presence of the smaller phase crystals within the spaces between the larger phase crystals. The composition is carefully prepared by a process wherein palladium and an amount of boron sufficient to place the boron in solid solution, but insufficient to combine with the palladium, are placed together and repeatedly are melted, cooled and turned over until sufficiently mixed.Type: GrantFiled: August 23, 2004Date of Patent: June 3, 2008Assignee: The United States of America as represented by the Secretary of the NavyInventors: Melvin H. Miles, M. Ashraf Imam
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Publication number: 20080093585Abstract: A composite material includes lithium hydride particles dispersed within lithium to form a lithium-lithium hydride composite. The lithium-lithium hydride composite has increased strength over pure lithium and similar soft X-ray transmission characteristics as pure lithium. A soft X-ray blast window may be made from the lithium-lithium hydride composite with increased reliability and cost effectiveness. A method for making a composite material includes dispersing lithium hydride into lithium metal using a variety of dispersion techniques.Type: ApplicationFiled: October 23, 2006Publication date: April 24, 2008Inventors: Nino R. Pereira, M. Ashraf Imam
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Patent number: 7279292Abstract: A method for identifying low grade astrocytoma cells in a sample is provided, wherein the method distinguishes between low grade astrocytoma cells and normal astrocytes, thus permitting early diagnosis of astrocytoma. The method uses antibody directed against J1-31 to test astrocytes in the sample for the presence or absence of J1-31 polypeptide, the low grade astrocytoma cells being characterized by the absence of J1-31 while normal astrocytes are characterized by the presence of J1-31.Type: GrantFiled: August 17, 2006Date of Patent: October 9, 2007Assignees: Governors of the University of Alberta, Huntington Medical Research InstitutesInventors: S. Ashraf Imam, Sudarshan Malhotra
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Patent number: 6764561Abstract: A palladium-boron composition and methods of making and using same are provided. In one aspect, the invention comprises an alloy comprising palladium and boron, the boron being in solid solution in the palladium and the alloy having a two-phase structure, wherein each phase of the two-phase structure has the same crystal structure as the other phase and has a different set of lattice parameters from the other phase such that the palladium is greatly hardened by the presence of the smaller phase crystals within the spaces between the larger phase crystals. The composition is carefully prepared by a process wherein palladium and an amount of boron sufficient to place the boron in solid solution, but insufficient to combine with the palladium, are placed together and repeatedly arc melted, cooled and turned over until sufficiently mixed.Type: GrantFiled: August 30, 2000Date of Patent: July 20, 2004Assignee: The United States of America as represented by the Secretary of the NavyInventors: Melvin H. Miles, M. Ashraf Imam
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Patent number: 6700067Abstract: A high temperature superconducting composite rod, wire or tape is formed by filling the open cells of a reticulated foam structure made of silver, silver alloy, gold or gold alloy with a superconducting ceramic oxide or precursor, compacting the filled structure and forming it into a rod, wire or tape and heating it to melt and/or texture the superconducting ceramic oxide. The resulting composite has continuous ligaments of metal throughout a continuous region of superconducting ceramic oxide.Type: GrantFiled: July 10, 2000Date of Patent: March 2, 2004Assignee: The Secretary of the United States of America as represented by the Secretary of the NavyInventors: Donald U. Gubser, M. Ashraf Imam
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Publication number: 20030073146Abstract: A method for identifying low grade astrocytoma cells in a sample is provided, wherein the method distinguishes between low grade astrocytoma cells and normal astrocytes, thus permitting early diagnosis of astrocytoma. The method uses antibody directed against JI-31 to test astrocytes in the sample for the presence or absence of JI-31 polypeptide, the low grade astrocytoma cells being characterized by the absence of JI-31 while normal astrocytes are characterized by the presence of JI-31.Type: ApplicationFiled: October 10, 2002Publication date: April 17, 2003Inventors: S. Ashraf Imam, Sudarshan Malhotra