Abstract: The use of fermented camel milk with a honey propolis engineered probiotic for treating bowel disorders (BD). The honey propolis is used as a synergistic supplement to engineer the probiotic bacterium, Enterococcus faecium (EF), at a defined bacterial load, propolis concentration, and incubation period. The engineered EF is included with fermented camel's milk, which is then administered orally to those suffering from a BD. Effective treatment can be observed both through reduced adverse effects, as well as reduced levels of immune-modulatory markers such as TNF ?, VEGF-1, IL-1?, IFN-? IFN T ?-6 and TGF-?.