Abstract: The present invention provides high throughput assays for identifying compounds that modulate a contractile function, as well as devices suitable for use in these assays.

Abstract: The present invention relates to synergistic antimicrobial compositions comprising quaternary ammonium compound and antimicrobial active, process of preparing the same and their use. The compositions of the present invention possess activity at lower concentration of the actives and are environmentally benign.

Abstract: Synthesizing a metal-organic-framework includes combining a first solution and a second solution to yield a synthetic medium. The first solution typically includes a solvent, an inhibitor, a metal capping agent, a ligand, and a metal source, and the second solution typically includes a deprotonating agent and a buffer. The metal and the ligand are reacted in the synthetic medium to yield a two-dimensional metal-organic-framework in the form of a nanosheet, and the two-dimensional metal-organic-framework is removed from the synthetic medium. The two-dimensional metal-organic framework has an aspect ratio of at least 300 or at least 1000.

Abstract: The present invention discloses synergistic antimicrobial composition comprises zinc pyrithione and a zinc salt of pyridine carboxylic acid.

Abstract: Embodiments herein relate to gas distribution apparatuses. In one aspect, the disclosure herein relates to a showerhead including a body having an upper surface and a lower surface. A thermal choke is disposed adjacent a perimeter of the body. The thermal choke includes a plurality of interleaved channels. One or more apertures are disposed between the upper surface and the lower surface of the body.

Abstract: The present invention provides devices, constructs, and methods of use of polymeric fiber-scaffolded engineered tissues and assays for identifying compounds that modulate a contractile function, using such devices and constructs.

Abstract: A microfluidic structure is formed with one or more microfluidic channels for receiving fluid and passing the fluid through a channel in communication with a collection chamber integrated with that channel through a transition stage that allows the collection chamber to gather targets within the fluid, such as cells, including circulating tumor cells in blood. The transition stage may be formed for an asymmetrical configuration with an obstacle and chamfered face configuration. A gas permeable membrane provides perfusion control for directing gas to the collection chamber. Porous elements provide bubble venting from the fluid flow.

Abstract: The present invention provides high throughput assays for identifying compounds that modulate a contractile function, as well as devices suitable for use in these assays.

Abstract: The present invention discloses a stable biocidal composition with enhanced antifungal activity at low concentration of active (s) and a process for preparing the same. The composition comprises: zinc pyrithione, C8-C18 quaternary ammonium salt (preferably cetylpyridinium chloride), water miscible glycol/polyol/glycol ether/lactam, organic amine and/or alkanol amine. The composition can be formulated into: hair care formulations, antidandruff hair care formulations, water based paints, coatings, adhesives, hard surface cleaners, fabric care compositions, wood products, plastic products and medical products. The biocidal compositions and the resulting formulations are transparent or opaque and are stable at varying pH and humidity conditions.

Abstract: Embodiments described herein provide a remote plasma system utilizing a microwave source. Additionally, generation and deposition techniques for 2D transition metal chalcogenides with large area uniformity utilizing microwave assisted generation of radicals is disclosed. Plasma may be generated remotely utilizing the microwave source. A processing platform configured to deposit 2D transition metal chalcogenides is also disclosed.

Abstract: The present invention provides high throughput assays for identifying compounds that modulate a contractile function, as well as devices suitable for these assays.

Abstract: The present invention discloses synergistic antimicrobial composition comprises zinc pyrithione and a zinc salt of pyridine carboxylic acid.

Abstract: A slotted microfilter is coated with a phase changeable material having a hydrophobic state under a first temperature and a hydrophilic state under a second temperature. An example coating material is poly(N-isopropylacrylamide) (“PIPAAm”). The microfilter can be controlled to switch between a capture state where circulating tumor cells are captured by the microfilter and a release state, where viable tumor cells are released from capture for analysis, e.g., single cell phenotypic and genomic analysis, or for ex vivo culture growth.

Abstract: The present invention discloses a stable biocidal composition with enhanced anti-fungal activity at low concentration of active(s) and a process for preparing the same. The composition comprises: zinc pyrithione, C8-C18 quaternary ammonium salt (preferably cetylpyridinium chloride), water miscible glycol/polyol/glycol ether/lactam, organic amine and/or alkanol amine The composition can be formulated into: hair care formulations, antidandruff hair care formulations, water based paints, coatings, adhesives, hard surface cleaners, fabric care compositions, wood products, plastic products and medical products. The biocidal compositions and the resulting formulations are transparent or opaque and are stable at varying pH and humidity conditions.

Abstract: Embodiments described herein provide a remote plasma system utilizing a microwave source. Additionally, generation and deposition techniques for 2D transition metal chalcogenides with large area uniformity utilizing microwave assisted generation of radicals is disclosed. Plasma may be generated remotely utilizing the microwave source. A processing platform configured to deposit 2D transition metal chalcogenides is also disclosed.

Abstract: Methods and apparatus for processing a substrate are provided herein. In some embodiments, a substrate processing chamber includes: a chamber body; a chamber lid assembly having a housing enclosing a central channel that extends along a central axis and has an upper portion and a lower portion; a lid plate coupled to the housing and having a contoured bottom surface that extends downwardly and outwardly from a central opening coupled to the lower portion of the central channel to a peripheral portion of the lid plate; and a gas distribution plate disposed below the lid plate and having a plurality of apertures disposed through the gas distribution plate.

Abstract: The present invention discloses a stable biocidal composition with enhanced antifungal activity at low concentration of active (s) and a process for preparing the same. The composition comprises: zinc pyrithione, C8-C18 quaternary ammonium salt (preferably cetylpyridinium chloride), water miscible glycol/polyol/glycol ether/lactam, organic amine and/or alkanol amine. The composition can be formulated into: hair care formulations, antidandruff hair care formulations, water based paints, coatings, adhesives, hard surface cleaners, fabric care compositions, wood products, plastic products and medical products. The biocidal compositions and the resulting formulations are transparent or opaque and are stable at varying pH and humidity conditions.

Abstract: The present invention relates to an improved process for the preparation of azilsartan or its esters or salts thereof. Specifically, the invention provides a method for the preparation of highly pure methyl 1-[[2?-(4,5-dihydro-5-oxo-4H-1,2,4-oxa-diazol-3-yl)biphenyl-4-yl]methyl]-2-ethoxy-1H-benzimidazole-7-carboxylate an intermediate compound of formula (4) for azilsartan medoxomil with reduced content of desethyl impurity. The invention also involves the use of highly pure methyl 1-[[2?-(4,5-dihydro-5-oxo-4H-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl]-2-ethoxy-1H-benzimidazole-7-carboxylate in the preparation of azilsartan or its esters or salts thereof, preferably medoxomil with reduced content of desethyl impurity.

Abstract: The present invention provides devices, constructs, and methods of use of polymeric fiber-scaffolded engineered tissues and assays for identifying compounds that modulate a contractile function, using such devices and constructs.

Abstract: An improved catalytic process for the production of pyridine carboxylic acid amides, by catalytic hydration reaction of pyridine nitriles with solid heterogeneous catalyst wherein the process involve effective utilization and recycling of the catalytic components, and reactants.