Patents by Inventor Ashvinikumar Gavai

Ashvinikumar Gavai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ALKYLENE BRIDGED SULTAM COMPOUNDS USEFUL AS MODULATORS OF NUCLEAR HORMONE RECEPTOR FUNCTION
    Publication number: 20080090883
    Abstract: Disclosed are sultam compounds of Formula (I) or a pharmaceutically-acceptable salt thereof. Also disclosed are methods of using such compounds in the treatment of at least one nuclear hormone receptor-associated condition, such as, for example, cancer and immune disorders, and at least one pharmaceutical composition comprising such compounds.
    Type: Application
    Filed: September 5, 2007
    Publication date: April 17, 2008
    Inventors: Weifang Shan, James Balog, Andrew Nation, Ashvinikumar Gavai, Wen-Ching Han, Mark Salvati
  • PYRROLOTRIAZINE COMPOUNDS USEFUL AS KINASE INHIBITORS AND METHODS OF TREATING KINASE-ASSOCIATED CONDITIONS THEREWITH
    Publication number: 20070004731
    Abstract: The invention relates to at least one pyrrolotriazine derivative, at least one pharmaceutical composition comprising at least one pyrrolotriazine derivative, and at least one method of using at least one pyrrolotriazine derivative to treat at least one kinase associated condition.
    Type: Application
    Filed: June 27, 2006
    Publication date: January 4, 2007
    Applicant: Bristol-Myers Squibb Company
    Inventors: Harold Mastalerz, Dolatrai Vyas, George Trainor, Ashvinikumar Gavai
  • Pyrrolotriazine compounds useful as kinase inhibitors and methods of treating kinase-associated conditions therewith
    Publication number: 20070004732
    Abstract: The invention relates to at least one pyrrolotriazine derivative, at least one pharmaceutical composition comprising at least one pyrrolotriazine derivative, and at least one method of using at least one pyrrolotriazine derivative to treat at least one kinase associated condition.
    Type: Application
    Filed: June 27, 2006
    Publication date: January 4, 2007
    Inventors: Ashvinikumar Gavai, Ping Chen, Derek Norris
  • Pyrrolotriazine compounds useful as kinase inhibitors and methods of treating kinase-associated conditions therewith
    Publication number: 20070004733
    Abstract: The invention relates to at least one pyrrolotriazine derivative, at least one pharmaceutical composition comprising at least one pyrrolotriazine derivative, and at least one method of using at least one pyrrolotriazine derivative to treat at least one kinase associated condition.
    Type: Application
    Filed: June 27, 2006
    Publication date: January 4, 2007
    Inventors: Ping Chen, Derek Norris, Ashvinikumar Gavai
  • PYRROLOTRIAZINE COMPOUNDS AS KINASE INHIBITORS
    Publication number: 20060264438
    Abstract: The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The formula I compounds inhibit tyrosine kinase activity of growth factor receptors such as HER1, HER2 and HER4 thereby making them useful as antiproliferative agents. The formula I compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.
    Type: Application
    Filed: June 26, 2006
    Publication date: November 23, 2006
    Applicant: Bristol-Myers Squibb Company
    Inventors: Brian Fink, Ashvinikumar Gavai, Gregory Vite, Ping Chen, Harold Mastalerz, Derek Norris, John Tokarski, Yufen Zhao, Wen-Ching Han
  • ATP competitive kinase inhibitors
    Publication number: 20060217369
    Abstract: The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The formula I compounds inhibit tyrosine kinase activity of growth factor receptors such as HER1, HER2 and HER4 thereby making them useful as antiproliferative agents. The formula I compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.
    Type: Application
    Filed: March 27, 2006
    Publication date: September 28, 2006
    Inventors: Ashvinikumar Gavai, Ping Chen, Yufen Zhao
  • Synthetic process
    Publication number: 20060155125
    Abstract: The present invention provides a process for preparing compounds of formula (IV) or a pharmaceutically acceptable salt thereof. The compounds prepared by the process of the invention inhibit tyrosine kinase activity of growth factor receptors such as HER1, HER2 and HER4 thereby making them useful as antiproliferative agents for the treatment of cancer and other diseases.
    Type: Application
    Filed: December 21, 2005
    Publication date: July 13, 2006
    Inventors: Ping Chen, Derek Norris, Ashvinikumar Gavai
  • Pyrrolotriazine compounds
    Publication number: 20060089358
    Abstract: The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The compounds of the invention inhibit tyrosine kinase activity of growth factor receptors such as HER1, HER2 and HER4 thereby making them useful as antiproliferative agents. The compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.
    Type: Application
    Filed: October 19, 2005
    Publication date: April 27, 2006
    Inventors: Ashvinikumar Gavai, Wen-Ching Han, Yufen Zhao, Ping Chen
  • Pyrrolotriazine compounds
    Publication number: 20060014745
    Abstract: The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The compounds of the invention inhibit tyrosine kinase activity of growth factor receptors such as HER1, HER2 and HER4 thereby making them useful as antiproliferative agents. The compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.
    Type: Application
    Filed: June 21, 2005
    Publication date: January 19, 2006
    Inventors: Ashvinikumar Gavai, Harold Mastalerz, Jean-Paul Daris, Pierre Dextraze, Philippe Lapointe, Edward Ruediger, Dolatrai Vyas, Guifen Zhang
  • Fused tricyclic compounds as inhibitors of 17beta-hydroxysteroid dehydrogenase 3
    Publication number: 20050250753
    Abstract: Fused tricyclic compounds, methods of using such compounds in the treatment of hormone sensitive diseases such as prostate cancer, and pharmaceutical compositions containing such compounds.
    Type: Application
    Filed: February 25, 2005
    Publication date: November 10, 2005
    Inventors: Brian Fink, Ashvinikumar Gavai, Gregory Vite, Wen-Ching Han, Raj Misra, Hai-Yun Xiao, Derek Norris, John Tokarski
  • Synthetic process
    Publication number: 20050209454
    Abstract: The present invention provides a process for preparing compounds of formula (I) or a pharmaceutically acceptable salt thereof. The compounds prepared by the process of the invention inhibit tyrosine kinase activity of growth factor receptors such as HER1, HER2 and HER4 thereby making them useful as antiproliferative agents for the treatment of cancer and other diseases.
    Type: Application
    Filed: December 9, 2004
    Publication date: September 22, 2005
    Inventors: Shankar Swaminathan, Ashvinikumar Gavai, Junying Fan, Bharat Patel, Derek Norris, Richard Corbett, Bin Zheng
  • Di-substituted pyrrolotrizine compounds
    Publication number: 20050197339
    Abstract: The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The compounds of the invention inhibit tyrosine kinase activity of growth factor receptors such as HER1, HER2 and HER4 thereby making them useful as antiproliferative agents for the treatment of cancer and other diseases.
    Type: Application
    Filed: December 22, 2004
    Publication date: September 8, 2005
    Inventors: Ashvinikumar Gavai, Wen-Ching Han, Ping Chen, Edward Ruediger, Harold Mastalerz, Brian Fink, Derek Norris
  • Fused heterotricyclic compounds as inhibitors of 17beta-hydroxysteroid dehydrogenase 3
    Publication number: 20050192310
    Abstract: Fused heterotricyclic compounds, methods of using such compounds in the treatment of hormone sensitive diseases such as prostate cancer, and pharmaceutical compositions containing such compounds.
    Type: Application
    Filed: February 25, 2005
    Publication date: September 1, 2005
    Inventors: Ashvinikumar Gavai, Derek Norris, Wen-Ching Han, Gregory Vite, Brian Fink, John Tokarski
  • Pyrrolotriazine compounds as kinase inhibitors
    Publication number: 20050182058
    Abstract: The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The formula I compounds inhibit tyrosine kinase activity of growth factor receptors such as HER1, HER2 and HER4 thereby making them useful as antiproliferative agents. The formula I compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.
    Type: Application
    Filed: December 22, 2004
    Publication date: August 18, 2005
    Inventors: Brian Fink, Ashvinikumar Gavai, Gregory Vite, Ping Chen, Harold Mastalerz, Derek Norris, John Tokarski, Yufen Zhao, Wen-Ching Han