Patents by Inventor Ashwin K. Rao
Ashwin K. Rao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240065585Abstract: The invention provides amperometric analyte sensor systems comprising one or more electrodes designed to monitor in vivo levels of 3-hydroxybutyrate (and optionally glucose as well) in order to facilitate the management of diabetic ketoacidosis. The invention further includes compositions, elements and methods useful with such amperometric analyte sensor systems.Type: ApplicationFiled: August 7, 2023Publication date: February 29, 2024Applicant: Medtronic MiniMed, Inc.Inventors: Quyen B. Ong, Michal Galik, Hanieh Ghadimi, Carlos E. Maldonado, Ashwin K. Rao, Robert C. Mucic
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Patent number: 11904146Abstract: A medicine delivery and tracking system includes a medicine injection pen and a delivery port. The pen includes a needle through which medicine is dispensed and an electronic unit configured to at least one of log dispensing of medicine from the pen, control dispensing of medicine from the pen, or communicate regarding dispensing of medicine from the pen. Alternatively, the electronic unit may be part of a separate computing device. The delivery port is configured for attachment to a user and to receive the needle of the pen such that medicine dispensed from the pen is dispensed into the delivery port and through the delivery port to the user. The delivery port includes a detector mechanism configured to detect a presence of the pen and, in response thereto, to communicate a signal to the electronic unit for use in the at least one of logging, controlling, or communicating.Type: GrantFiled: June 8, 2021Date of Patent: February 20, 2024Assignee: Medtronic MiniMed, Inc.Inventors: Ellis Garai, Ashwin K. Rao
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Publication number: 20240023849Abstract: Embodiments of the invention provide compositions useful in implantable devices such as analyte sensors as well as methods for making and using such compositions and devices. In typical embodiments of the invention, the device is a glucose sensor comprising an analyte modulating layer formed from acrylate hydrogel composition that modulates the diffusion of glucose through the analyte modulating layer and which further comprises a bioactive agent selected to enhance the biocompatibility of analyte sensors when implanted in vivo.Type: ApplicationFiled: June 29, 2023Publication date: January 25, 2024Applicant: Medtronic MiniMed, Inc.Inventors: Daniel E. Pesantez, Ashwin K. Rao, Inthirai Somasuntharam
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Publication number: 20230404448Abstract: A method for compensating for a life-lengthening agent for a glucose sensor includes accessing first and second electrochemical impedance spectroscopy (EIS) values of at least one parameter based on first and second EIS procedures performed on EIS signals from a working electrode of the glucose sensor, calculating a change in the at least one parameter between the first and second EIS values, estimating a concentration of the agent based on the change in the at least one parameter, and calculating a model effect in response to the concentration. In a case where the model effect is not greater than the threshold, the method further includes adjusting a sensor glucose value based on the concentration and sensor signals from the working electrode, and displaying the adjusted sensor glucose value.Type: ApplicationFiled: April 19, 2023Publication date: December 21, 2023Inventors: Ellis Garai, Sarkis D. Aroyan, Anuj M. Patel, Ashwin K. Rao
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Patent number: 11793930Abstract: A fluid infusion system includes a housing configured to be adhesively coupled to an anatomy of a user, and a tube configured to extend from the housing for insertion into the anatomy of the user. The tube includes a plurality of conduits defined within the tube. The plurality of conduits include a fluid delivery conduit configured to facilitate a fluidic connection between a fluid source and the anatomy of the user, and one or more conduits configured to accommodate a plurality of electrodes for determining a physiological characteristic of the user.Type: GrantFiled: June 4, 2020Date of Patent: October 24, 2023Assignee: Medtronic MiniMed, Inc.Inventors: Chia-Hung Chiu, Rebecca K. Gottlieb, Ellis Garai, Akhil Srinivasan, Andrea Varsavsky, Adam S. Trock, Ashwin K. Rao, Hsifu Wang, Daniel E. Pesantez, Isabella Ella Miya, Xinrui Zhang, Guruguhan Meenakshisundaram
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Publication number: 20230310341Abstract: The invention provides a skin adhesive patch that inhibits skin irritation by releasing an anti-inflammatory agent such as a corticosteroid topically on the skin surface. Embodiments of the invention can be adapted for use with a wide variety of adhesive patches that are used to couple medical components to the skin of patients such as the devices that diabetic patients use including insulin infusion sets, patch pumps, and all-in-one patch sets.Type: ApplicationFiled: March 29, 2023Publication date: October 5, 2023Applicant: Medtronic MiniMed, Inc.Inventors: Ellis Garai, Ashwin K. Rao, Margaret R. Miller, Sarkis D. Aroyan
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Patent number: 11718865Abstract: Embodiments of the invention provide multilayer analyte sensors having elements and/or architectures that function to improve oxygen delivery to sensor enzymes in manner that enhances sensor function, as well as methods for making and using such sensors. Typical embodiments of the invention include glucose sensors used in the management of diabetes.Type: GrantFiled: July 26, 2019Date of Patent: August 8, 2023Assignee: MEDTRONIC MINIMED, INC.Inventors: Daniel E. Pesantez, Ashwin K. Rao, Ellis Garai, Rui Kong, Michael E. Miller
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Patent number: 11642454Abstract: A fluid infusion system includes a housing configured to be adhesively coupled to an anatomy of the user. The housing comprises a communication device configured to wirelessly communicate a physiological characteristic to a communication component of a fluid infusion device. The fluid infusion system includes a fluid flow path from the fluid infusion device into the anatomy of the user, and the fluid flow path is configured to extend from the housing for insertion into the anatomy of the user.Type: GrantFiled: June 4, 2020Date of Patent: May 9, 2023Assignee: Medtronic MiniMed, Inc.Inventors: Chia-Hung Chiu, Rebecca K. Gottlieb, Ellis Garai, Akhil Srinivasan, Andrea Varsavsky, Adam S. Trock, Ashwin K. Rao, Hsifu Wang, Daniel E. Pesantez, Isabella Ella Miya, Xinrui Zhang, Guruguhan Meenakshisundaram
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Publication number: 20230140353Abstract: A medical device includes a base having a needle channel and a first surface configured to be secured to a patient's skin. An insertable member is configured to be secured to the base with a length portion of the insertable member extending out of the needle channel at the first surface, for insertion through the patient's skin at an insertion site. A septum extends across the needle channel. The septum has a body through which an insertion needle may be selectively extended to facilitate the subcutaneous insertion of the length portion of the insertable member. The septum provides a liquid seal across the needle channel. The needle channel and the septum provide a sealed volume in which a limited amount of blood or other fluid from the insertion site may be held.Type: ApplicationFiled: November 2, 2021Publication date: May 4, 2023Inventors: Ellis Garai, Ashwin K. Rao, Lawrence S. Ring
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Publication number: 20230123613Abstract: The invention provides amperometric analyte sensor systems comprising one or more electrodes designed to monitor in vivo levels of 3-hydroxybutyrate (and optionally glucose as well) in order to facilitate the management of diabetic ketoacidosis. The invention further includes compositions, elements and methods useful with such amperometric analyte sensor systems.Type: ApplicationFiled: October 14, 2021Publication date: April 20, 2023Applicant: Medtronic MiniMed, Inc.Inventors: Ashwin K. Rao, Quyen B. Ong, Michael E. Miller, Sarnath Chattaraj, Guangping Zhang, Poonam Gulati, Ariel Reider, Mohsen Askarinya, Michael N. Missaghi, Chi-En Lin, Xin Heng, Inthirai Somasuntharam, Melissa Tsang, Carlos E. Maldonado, Akhil Srinivasan
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Publication number: 20230113175Abstract: Embodiments of the invention provide compositions useful in implantable devices such as analyte sensors as well as methods for making and using such compositions and devices. In typical embodiments of the invention, the device is a glucose sensor comprising a polymeric composition disposed on a flexible assembly within the sensor that includes amounts of one or more immunosuppressant agents designed to provide such sensors with improved material properties such as enhanced biocompatibility.Type: ApplicationFiled: October 8, 2021Publication date: April 13, 2023Applicant: Medtronic MiniMed, Inc.Inventors: Ellis Garai, Jenn-Hann L. Wang, Ashwin K. Rao
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Publication number: 20220387723Abstract: A medicine delivery and tracking system includes a medicine injection pen and a delivery port. The pen includes a needle through which medicine is dispensed and an electronic unit configured to at least one of log dispensing of medicine from the pen, control dispensing of medicine from the pen, or communicate regarding dispensing of medicine from the pen. Alternatively, the electronic unit may be part of a separate computing device. The delivery port is configured for attachment to a user and to receive the needle of the pen such that medicine dispensed from the pen is dispensed into the delivery port and through the delivery port to the user. The delivery port includes a detector mechanism configured to detect a presence of the pen and, in response thereto, to communicate a signal to the electronic unit for use in the at least one of logging, controlling, or communicating.Type: ApplicationFiled: June 8, 2021Publication date: December 8, 2022Inventors: Ellis Garai, Ashwin K. Rao
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Publication number: 20220240823Abstract: Embodiments of the invention provide amperometric analyte sensors having optimized elements such as interference rejection membranes, and associated architectures, as well as methods for making and using such sensors. While embodiments of the innovation can be used in a variety of contexts, typical embodiments of the invention include glucose sensors used in the management of diabetes.Type: ApplicationFiled: January 29, 2021Publication date: August 4, 2022Applicant: Medtronic MiniMed, Inc.Inventors: Ashwin K. Rao, Qingling Yang, Ellis Garai, Daniel E. Pesantez
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Muting glucose sensor oxygen response and reducing electrode edge growth with pulsed current plating
Patent number: 11266332Abstract: The invention disclosed herein includes amperometric glucose sensors having electrodes formed from processes that electrodeposit platinum black in a manner that produces relatively smooth three dimensional metal architectures, ones that contribute to sensor reliability and stability. Embodiments of the invention provide analyte sensors having such uniform electrode architectures as well as methods for making and using these sensor electrodes. A number of working embodiments of the invention are shown to be useful in amperometric glucose sensors worn by diabetic individuals.Type: GrantFiled: August 27, 2019Date of Patent: March 8, 2022Assignee: Medtronic MiniMed, inc.Inventors: Ting Huang, Ashwin K. Rao, Rajiv Shah, Qingling Yang -
Publication number: 20210024972Abstract: Embodiments of the invention provide multilayer analyte sensors having elements and/or architectures that function to improve oxygen delivery to sensor enzymes in manner that enhances sensor function, as well as methods for making and using such sensors. Typical embodiments of the invention include glucose sensors used in the management of diabetes.Type: ApplicationFiled: July 26, 2019Publication date: January 28, 2021Applicant: MEDTRONIC MINIMED, INC.Inventors: Daniel E. Pesantez, Ashwin K. Rao, Ellis Garai, Rui Kong, Michael E. Miller
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Publication number: 20210003564Abstract: Devices, patch sensors, and methods for detecting a ketone body are disclosed. An exemplary device includes a collection apparatus for collecting a sample amount of interstitial fluid and a ketone body indicator having an initial negative state and having a positive state when at least a threshold value of the ketone body is collected in the sample amount.Type: ApplicationFiled: September 18, 2020Publication date: January 7, 2021Inventors: Ashwin K. Rao, Rebecca K. Gottlieb, Quyen Ong
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Publication number: 20200384197Abstract: A fluid infusion system includes a housing configured to be adhesively coupled to an anatomy of the user. The housing comprises a communication device configured to wirelessly communicate a physiological characteristic to a communication component of a fluid infusion device. The fluid infusion system includes a fluid flow path from the fluid infusion device into the anatomy of the user, and the fluid flow path is configured to extend from the housing for insertion into the anatomy of the user.Type: ApplicationFiled: June 4, 2020Publication date: December 10, 2020Inventors: Chia-Hung Chiu, Rebecca K. Gottlieb, Ellis Garai, Akhil Srinivasan, Andrea Varsavsky, Adam S. Trock, Ashwin K. Rao, Hsifu Wang, Daniel E. Pesantez, Isabella Ella Miya, Xinrui Zhang, Guruguhan Meenakshisundaram
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Publication number: 20200384193Abstract: A fluid infusion system includes a housing configured to be adhesively coupled to an anatomy of a user, and a tube configured to extend from the housing for insertion into the anatomy of the user. The tube includes a plurality of conduits defined within the tube. The plurality of conduits include a fluid delivery conduit configured to facilitate a fluidic connection between a fluid source and the anatomy of the user, and one or more conduits configured to accommodate a plurality of electrodes for determining a physiological characteristic of the user.Type: ApplicationFiled: June 4, 2020Publication date: December 10, 2020Inventors: Chia-Hung Chiu, Rebecca K. Gottlieb, Ellis Garai, Akhil Srinivasan, Andrea Varsavsky, Adam S. Trock, Ashwin K. Rao, Hsifu Wang, Daniel E. Pesantez, Isabella Ella Miya, Xinrui Zhang, Guruguhan Meenakshisundaram
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MUTING GLUCOSE SENSOR OXYGEN RESPONSE AND REDUCING ELECTRODE EDGE GROWTH WITH PULSED CURRENT PLATING
Publication number: 20200060586Abstract: The invention disclosed herein includes amperometric glucose sensors having electrodes formed from processes that electrodeposit platinum black in a manner that produces relatively smooth three dimensional metal architectures, ones that contribute to sensor reliability and stability. Embodiments of the invention provide analyte sensors having such uniform electrode architectures as well as methods for making and using these sensor electrodes. A number of working embodiments of the invention are shown to be useful in amperometric glucose sensors worn by diabetic individuals.Type: ApplicationFiled: August 27, 2019Publication date: February 27, 2020Applicant: Medtronic MiniMed, Inc.Inventors: Ting Huang, Ashwin K. Rao, Rajiv Shah, Qingling Yang -
Muting glucose sensor oxygen response and reducing electrode edge growth with pulsed current plating
Patent number: 10426383Abstract: The invention disclosed herein includes amperometric glucose sensors having electrodes formed from processes that electrodeposit platinum black in a manner that produces relatively smooth three dimensional metal architectures, ones that contribute to sensor reliability and stability. Embodiments of the invention provide analyte sensors having such uniform electrode architectures as well as methods for making and using these sensor electrodes. A number of working embodiments of the invention are shown to be useful in amperometric glucose sensors worn by diabetic individuals.Type: GrantFiled: February 27, 2013Date of Patent: October 1, 2019Assignee: MEDTRONIC MINIMED, INC.Inventors: Ting Huang, Ashwin K. Rao, Rajiv Shah, Qingling Yang