Abstract: The invention provides a method for manipulation of microdroplets in a microdroplet array. The method includes selecting at least one microdroplet from the microdroplet array and identifying at least one object trapped within the selected microdroplet. Subsequent to identifying the manipulation, a multi-functional probe specific to the determined manipulation is selected. The object identified is then subjected to manipulation. The invention further provides a system for manipulation of microdroplets in a microdroplet array.

Abstract: The invention provides a micro-droplet array formation apparatus. The apparatus includes a first plate configured for delivering and/or extracting fluids, a second plate aligned to the first plate and configured for preparing the fluid and a third plate removably aligned to the second plate and is configured for forming a micro-droplet array of the prepared fluid.

Abstract: The invention provides an apparatus for formation of a micro-droplet array of a desired fluid. The apparatus comprises of a first plate configured for delivering and/or extracting fluids, a second plate aligned to the first plate and configured for preparing the fluid and a third plate removably aligned to the second plate and is configured for forming a micro-droplet array of the prepared fluid. The second plate has a first microfluidic circuit present on the top surface and is operatively connected to a second microfluidic circuit on the bottom surface. The microfluidic channel on the bottom surface of the second plate is provided with circular slots and is configured for trapping a single cellular entity in the wells.