Patents by Inventor Ashwin Raghunathan
Ashwin Raghunathan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11867660Abstract: Device and methods for controlling pH or ionic gradient comprising a multisite array of feedback electrode sets comprising electrodes and pH sensing elements. The electrodes can include a reference electrode, counter electrode, and a working electrode. The device and methods iteratively select an amount of current and/or voltage to be applied to each working electrode, apply the selected amount of current and/or voltage to each working electrode to change pH of a solution close to the working electrode, and measure the signal output of the sensing element. The multisite array can include feedback and non-feedback electrode sets.Type: GrantFiled: July 17, 2020Date of Patent: January 9, 2024Assignee: ROBERT BOSCH GMBHInventors: Christopher Johnson, Sam Kavusi, Nadezda Fomina, Habib Ahmad, Autumn Maruniak, Christoph Lang, Ashwin Raghunathan, Young Shik Shin, Armin Darvish, Efthymios Papageorgiou
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Patent number: 11561198Abstract: Device and methods for use in a biosensor comprising a multisite array of test sites, the device and methods being useful for modulating the binding interactions between a (biomolecular) probe or detection agent and an analyte of interest by modulating the pH or ionic gradient near the electrodes in such biosensor. An electrochemically active agent that is suitable for use in biological buffers for changing the pH of the biological buffers. Method for changing the pH of biological buffers using the electrochemically active agents. The methods of modulating the binding interactions provided in a biosensor, analytic methods for more accurately controlling and measuring the pH or ionic gradient near the electrodes in such biosensor, and analytic methods for more accurately measuring an analyte of interest in a biological sample.Type: GrantFiled: December 20, 2018Date of Patent: January 24, 2023Assignee: ROBERT BOSCH GMBHInventors: Christopher Johnson, Sam Kavusi, Nadezda Fomina, Habib Ahmad, Autumn Maruniak, Christoph Lang, Ashwin Raghunathan
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Publication number: 20220288587Abstract: A heater for a microfluidic test card is disclosed herein. In a general example embodiment, a test card for analyzing a fluid sample includes at least one substrate layer including a microchannel extending through at least a portion of one of the substrate layers, and a printed substrate layer that is bonded to or printed on one substrate layer of the at least one substrate layer. The printed substrate layer includes a heater printed on the printed substrate layer so as to align with at least a portion of the microchannel. The heater includes two electrodes aligned on opposite sides of the microchannel, and a plurality of heater bars electrically connecting the two electrodes. The plurality of heater bars includes a central heater bar disposed between outer heater bars.Type: ApplicationFiled: May 31, 2022Publication date: September 15, 2022Inventors: Ashwin Raghunathan, Steve Lee, Ryan Alan Revilla, Tej Rushikesh Patel
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Patent number: 11344886Abstract: A heater for a microfluidic test card is disclosed herein. In a general example embodiment, a test card for analyzing a fluid sample includes at least one substrate layer including a microchannel extending through at least a portion of one of the substrate layers, and a printed substrate layer that is bonded to or printed on one substrate layer of the at least one substrate layer. The printed substrate layer includes a heater printed on the printed substrate layer so as to align with at least a portion of the microchannel. The heater includes two electrodes aligned on opposite sides of the microchannel, and a plurality of heater bars electrically connecting the two electrodes. The plurality of heater bars includes a central heater bar disposed between outer heater bars.Type: GrantFiled: January 24, 2020Date of Patent: May 31, 2022Assignee: FluxErgy, LLCInventors: Ashwin Raghunathan, Steve Lee, Ryan Alan Revilla, Tej Rushikesh Patel
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Patent number: 11322217Abstract: A track and hold circuit includes a signal input terminal, a clock input terminal, an output terminal, a transistor, and a bootstrapping circuit with a transformer. The transistor includes a source, a drain, and a gate, where the source is coupled to the signal input terminal, and the drain is coupled to the output terminal. The transformer includes a primary winding coupled to the clock input terminal, and a secondary winding. The secondary winding is coupled between the source and the gate to control a gate-source voltage of the transistor.Type: GrantFiled: August 26, 2020Date of Patent: May 3, 2022Assignee: TEXAS INSTRUMENTS INCORPORATEDInventors: Ashwin Raghunathan, Marco Corsi, Baher Haroun, Seyed Miaad Seyed Aliroteh, Swaminathan Sankaran, Robert Floyd Payne
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Patent number: 10942146Abstract: Device and methods for use in a biosensor comprising a multisite array of test sites, the device and methods being useful for modulating the binding interactions between a (biomolecular) probe or detection agent and an analyte of interest by modulating the pH or ionic gradient near the electrodes in such biosensor. An electrochemically active agent that is suitable for use in biological buffers for changing the pH of the biological buffers. Method for changing the pH of biological buffers using the electrochemically active agents. The methods of modulating the binding interactions provided in a biosensor, analytic methods for more accurately controlling and measuring the pH or ionic gradient near the electrodes in such biosensor, and analytic methods for more accurately measuring an analyte of interest in a biological sample.Type: GrantFiled: April 3, 2017Date of Patent: March 9, 2021Assignee: ROBERT BOSCH GMBHInventors: Christopher Johnson, Sam Kavusi, Nadezda Fomina, Habib Ahmad, Autumn Maruniak, Christoph Lang, Ashwin Raghunathan
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Publication number: 20210065830Abstract: A track and hold circuit includes a signal input terminal, a clock input terminal, an output terminal, a transistor, and a bootstrapping circuit with a transformer. The transistor includes a source, a drain, and a gate, where the source is coupled to the signal input terminal, and the drain is coupled to the output terminal. The transformer includes a primary winding coupled to the clock input terminal, and a secondary winding. The secondary winding is coupled between the source and the gate to control a gate-source voltage of the transistor.Type: ApplicationFiled: August 26, 2020Publication date: March 4, 2021Applicant: Texas Instruments IncorporatedInventors: Ashwin Raghunathan, Marco Corsi, Baher Haroun, Seyed Miaad Seyed Aliroteh, Swaminathan Sankaran, Robert Floyd Payne
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Publication number: 20200363371Abstract: Device and methods for controlling pH or ionic gradient comprising a multisite array of feedback electrode sets comprising electrodes and pH sensing elements. The electrodes can include a reference electrode, counter electrode, and a working electrode. The device and methods iteratively select an amount of current and/or voltage to be applied to each working electrode, apply the selected amount of current and/or voltage to each working electrode to change pH of a solution close to the working electrode, and measure the signal output of the sensing element. The multisite array can include feedback and non-feedback electrode sets.Type: ApplicationFiled: July 17, 2020Publication date: November 19, 2020Inventors: Christopher Johnson, Sam Kavusi, Nadezda Fomina, Habib Ahmad, Autumn Maruniak, Christoph Lang, Ashwin Raghunathan, Young Shik Shin, Armin Darvish, Efthymios Papageorgiou
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Publication number: 20200238283Abstract: A heater for a microfluidic test card is disclosed herein. In a general example embodiment, a test card for analyzing a fluid sample includes at least one substrate layer including a microchannel extending through at least a portion of one of the substrate layers, and a printed substrate layer that is bonded to or printed on one substrate layer of the at least one substrate layer. The printed substrate layer includes a heater printed on the printed substrate layer so as to align with at least a portion of the microchannel. The heater includes two electrodes aligned on opposite sides of the microchannel, and a plurality of heater bars electrically connecting the two electrodes. The plurality of heater bars includes a central heater bar disposed between outer heater bars.Type: ApplicationFiled: January 24, 2020Publication date: July 30, 2020Inventors: Ashwin Raghunathan, Steve Lee, Ryan Alan Revilla, Tej Rushikesh Patel
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Patent number: 10514352Abstract: A system and method for monitoring outlier behavior in an array of n electrodes includes an electrical line, a switching circuit via which the electrodes are individually coupleable to the electrical line, a sensor; and processing circuitry, where, in each of m iterations: (i) a respective subset of electrodes is coupled by the switching circuit to the electrical line, (ii) the sensor senses an electrical parameter produced over the electrical line by the coupled subset of electrodes, and (iii) the processing circuitry obtains from the sensor a respective value of the electrical parameter, m being less than n, and the processing circuitry identifying those of the electrodes that exhibit outlier electrical behavior by finding electrical values to individually ascribe to individual ones of the electrodes of the array, which ascribed values can result in all of the respective values of all of the m iterations.Type: GrantFiled: January 4, 2016Date of Patent: December 24, 2019Assignee: Robert Bosch GmbHInventors: Ashwin Raghunathan, Sam Kavusi
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Patent number: 10379080Abstract: Device and methods for use in a biosensor comprising a multisite array of test sites, the device and methods being useful for modulating the binding interactions between a (biomolecular) probe or detection agent and an analyte of interest by modulating the pH or ionic gradient near the electrodes in such biosensor. An electrochemically active agent that is suitable for use in biological buffers for changing the pH of the biological buffers. Method for changing the pH of biological buffers using the electrochemically active agents. The methods of modulating the binding interactions provided in a biosensor, analytic methods for more accurately controlling and measuring the pH or ionic gradient near the electrodes in such biosensor, and analytic methods for more accurately measuring an analyte of interest in a biological sample.Type: GrantFiled: July 6, 2015Date of Patent: August 13, 2019Assignee: Robert Bosch GmbHInventors: Christopher Johnson, Sam Kavusi, Nadezda Fomina, Habib Ahmad, Autumn Maruniak, Christoph Lang, Ashwin Raghunathan
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Publication number: 20190137444Abstract: Device and methods for use in a biosensor comprising a multisite array of test sites, the device and methods being useful for modulating the binding interactions between a (biomolecular) probe or detection agent and an analyte of interest by modulating the pH or ionic gradient near the electrodes in such biosensor. An electrochemically active agent that is suitable for use in biological buffers for changing the pH of the biological buffers. Method for changing the pH of biological buffers using the electrochemically active agents. The methods of modulating the binding interactions provided in a biosensor, analytic methods for more accurately controlling and measuring the pH or ionic gradient near the electrodes in such biosensor, and analytic methods for more accurately measuring an analyte of interest in a biological sample.Type: ApplicationFiled: December 20, 2018Publication date: May 9, 2019Inventors: Christopher Johnson, Sam Kavusi, Nadezda Fomina, Habib Ahmad, Autumn Maruniak, Christoph Lang, Ashwin Raghunathan
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Patent number: 10041905Abstract: Device and methods for use in a biosensor comprising a multisite array of test sites, the device and methods being useful for modulating the binding interactions between a (biomolecular) probe or detection agent and an analyte of interest by modulating the pH or ionic gradient near the electrodes in such biosensor. An electrochemically active agent that is suitable for use in biological buffers for changing the pH of the biological buffers. Method for changing the pH of biological buffers using the electrochemically active agents. The methods of modulating the binding interactions provided in a biosensor, analytic methods for more accurately controlling and measuring the pH or ionic gradient near the electrodes in such biosensor, and analytic methods for more accurately measuring an analyte of interest in a biological sample.Type: GrantFiled: April 3, 2017Date of Patent: August 7, 2018Assignee: ROBERT BOSCH GMBHInventors: Christopher Johnson, Sam Kavusi, Nadezda Fomina, Habib Ahmad, Autumn Maruniak, Christoph Lang, Ashwin Raghunathan
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Patent number: 10011549Abstract: Device and methods for use in a biosensor comprising a multisite array of test sites, the device and methods being useful for modulating the binding interactions between a (biomolecular) probe or detection agent and an analyte of interest by modulating the pH or ionic gradient near the electrodes in such biosensor. An electrochemically active agent that is suitable for use in biological buffers for changing the pH of the biological buffers. Method for changing the pH of biological buffers using the electrochemically active agents. The methods of modulating the binding interactions provided in a biosensor, analytic methods for more accurately controlling and measuring the pH or ionic gradient near the electrodes in such biosensor, and analytic methods for more accurately measuring an analyte of interest in a biological sample.Type: GrantFiled: July 6, 2015Date of Patent: July 3, 2018Assignee: ROBERT BOSCH GMBHInventors: Christopher Johnson, Sam Kavusi, Nadezda Fomina, Habib Ahmad, Autumn Maruniak, Christoph Lang, Ashwin Raghunathan
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Publication number: 20170226037Abstract: Device and methods for use in a biosensor comprising a multisite array of test sites, the device and methods being useful for modulating the binding interactions between a (biomolecular) probe or detection agent and an analyte of interest by modulating the pH or ionic gradient near the electrodes in such biosensor. An electrochemically active agent that is suitable for use in biological buffers for changing the pH of the biological buffers. Method for changing the pH of biological buffers using the electrochemically active agents. The methods of modulating the binding interactions provided in a biosensor, analytic methods for more accurately controlling and measuring the pH or ionic gradient near the electrodes in such biosensor, and analytic methods for more accurately measuring an analyte of interest in a biological sample.Type: ApplicationFiled: April 3, 2017Publication date: August 10, 2017Inventors: Christopher Johnson, Sam Kavusi, Nadezda Fomina, Habib Ahmad, Autumn Maruniak, Christoph Lang, Ashwin Raghunathan
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Publication number: 20170205372Abstract: Device and methods for use in a biosensor comprising a multisite array of test sites, the device and methods being useful for modulating the binding interactions between a (biomolecular) probe or detection agent and an analyte of interest by modulating the pH or ionic gradient near the electrodes in such biosensor. An electrochemically active agent that is suitable for use in biological buffers for changing the pH of the biological buffers. Method for changing the pH of biological buffers using the electrochemically active agents. The methods of modulating the binding interactions provided in a biosensor, analytic methods for more accurately controlling and measuring the pH or ionic gradient near the electrodes in such biosensor, and analytic methods for more accurately measuring an analyte of interest in a biological sample.Type: ApplicationFiled: April 3, 2017Publication date: July 20, 2017Inventors: Christopher Johnson, Sam Kavusi, Nadezda Fomina, Habib Ahmad, Autumn Maruniak, Christoph Lang, Ashwin Raghunathan
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Publication number: 20170008825Abstract: Device and methods for use in a biosensor comprising a multisite array of test sites, the device and methods being useful for modulating the binding interactions between a (biomolecular) probe or detection agent and an analyte of interest by modulating the pH or ionic gradient near the electrodes in such biosensor. An electrochemically active agent that is suitable for use in biological buffers for changing the pH of the biological buffers. Method for changing the pH of biological buffers using the electrochemically active agents. The methods of modulating the binding interactions provided in a biosensor, analytic methods for more accurately controlling and measuring the pH or ionic gradient near the electrodes in such biosensor, and analytic methods for more accurately measuring an analyte of interest in a biological sample.Type: ApplicationFiled: July 6, 2015Publication date: January 12, 2017Inventors: Christopher Johnson, Sam Kavusi, Nadezda Fomina, Habib Ahmad, Autumn Maruniak, Christoph Lang, Ashwin Raghunathan
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Publication number: 20170010238Abstract: Device and methods for use in a biosensor comprising a multisite array of test sites, the device and methods being useful for modulating the binding interactions between a (biomolecular) probe or detection agent and an analyte of interest by modulating the pH or ionic gradient near the electrodes in such biosensor. An electrochemically active agent that is suitable for use in biological buffers for changing the pH of the biological buffers. Method for changing the pH of biological buffers using the electrochemically active agents. The methods of modulating the binding interactions provided in a biosensor, analytic methods for more accurately controlling and measuring the pH or ionic gradient near the electrodes in such biosensor, and analytic methods for more accurately measuring an analyte of interest in a biological sample.Type: ApplicationFiled: July 6, 2015Publication date: January 12, 2017Inventors: Christopher Johnson, Sam Kavusi, Nadezda Fomina, Habib Ahmad, Autumn Maruniak, Christoph Lang, Ashwin Raghunathan
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Publication number: 20160216225Abstract: A system and method for monitoring outlier behavior in an array of n electrodes includes an electrical line, a switching circuit via which the electrodes are individually coupleable to the electrical line, a sensor; and processing circuitry, where, in each of m iterations: (i) a respective subset of electrodes is coupled by the switching circuit to the electrical line, (ii) the sensor senses an electrical parameter produced over the electrical line by the coupled subset of electrodes, and (iii) the processing circuitry obtains from the sensor a respective value of the electrical parameter, m being less than n, and the processing circuitry identifying those of the electrodes that exhibit outlier electrical behavior by finding electrical values to individually ascribe to individual ones of the electrodes of the array, which ascribed values can result in all of the respective values of all of the m iterations.Type: ApplicationFiled: January 4, 2016Publication date: July 28, 2016Inventors: Ashwin RAGHUNATHAN, Sam KAVUSI
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Patent number: D954573Type: GrantFiled: November 6, 2019Date of Patent: June 14, 2022Assignee: Fluxergy, LLCInventors: Steve Lee, Ryan Revilla, Roy Heltsley, Ashwin Raghunathan